scholarly journals Spermine modified polymeric micelles with pH-sensitive drug release for targeted and enhanced antitumor therapy

RSC Advances ◽  
2019 ◽  
Vol 9 (20) ◽  
pp. 11026-11037 ◽  
Author(s):  
Yang Chen ◽  
Cejun Yang ◽  
Juan Mao ◽  
Haigang Li ◽  
Jinsong Ding ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Drug Release ◽  
Tumor Targeting ◽  
Polymeric Micelles ◽  
Ph Sensitive ◽  
Antitumor Therapy ◽  
Anti Cancer ◽  
Targeting Delivery

Tumor targeting delivery of SPM functionalized micelles via PTS binding and their endocytosis and pH-triggered endo/lysosome drug release for anti-cancer therapy.

Co-delivery of dual chemo-drugs with precisely controlled, high drug loading polymeric micelles for synergistic anti-cancer therapy

2020 ◽  
Vol 8 (3) ◽  
pp. 949-959 ◽  
Author(s):  
Yuchen Wu ◽  
Shixian Lv ◽  
Yongjuan Li ◽  
Hua He ◽  
Yong Ji ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Polymeric Micelles ◽  
Drug Loading ◽  
High Drug ◽  
Delivery Strategy ◽  
Anti Cancer ◽  
High Drug Loading

The introduction of donor-receptor coordination between micelles and drug payloads provides a precise co-delivery strategy for two different chemo-drugs with high drug loading and ROS responsiveness.

A photoacoustic approach for monitoring the drug release of pH-sensitive poly(β-amino ester)s

2014 ◽  
Vol 2 (37) ◽  
pp. 6271-6282 ◽  
Author(s):  
Zhongyu Duan ◽  
Yu-Juan Gao ◽  
Zeng-Ying Qiao ◽  
Gang Fan ◽  
Ya Liu ◽  
...  
Keyword(s):  
Drug Release ◽  
Polymeric Micelles ◽  
Graft Copolymers ◽  
Ph Sensitive ◽  
Photoacoustic Tomography ◽  
Hydrophobic Core ◽  
Amino Ester ◽  
Release Profiles

In this work, we prepared PEG modified poly(β-amino ester) graft copolymers with pH-sensitive properties. Doxorubicin (DOX) and squaraine (SQ) dye as a photoacoustic tomography (PAT) reporter molecule were loaded into the hydrophobic core of polymeric micelles, and their release profiles investigated using the PAT technique.

Multi-Activated Polymeric Micelles with Charge-Conversion and ROS-Controlled Drug Release for Efficient Cancer Therapy

2017 ◽  
Vol 13 (8) ◽  
pp. 946-959 ◽  
Author(s):  
Changzhen Sun ◽  
Yan Liang ◽  
Mingying Zhao ◽  
Na Hao ◽  
Long Xu ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Drug Release ◽  
Polymeric Micelles ◽  
Controlled Drug Release

pH-Sensitive micelles with mitochondria-targeted and aggregation-induced emission characterization: synthesis, cytotoxicity and biological applications

2018 ◽  
Vol 6 (11) ◽  
pp. 2998-3008 ◽  
Author(s):  
Jieming Li ◽  
Yan Liu ◽  
Huilan Li ◽  
Wei Shi ◽  
Xinzhou Bi ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Tumor Targeting ◽  
Ph Sensitive ◽  
Biological Applications ◽  
Aggregation Induced Emission ◽  
Subcellular Organelle

Subcellular organelle-specific reagents for simultaneous tumor targeting, imaging, and treatment are of enormous interest in cancer therapy.

scholarly journals Drug Delivery: Dimeric Drug Polymeric Micelles with Acid‐Active Tumor Targeting and FRET‐Traceable Drug Release (Adv. Mater. 3/2018)

2018 ◽  
Vol 30 (3) ◽  
pp. 1870020 ◽  
Author(s):  
Xing Guo ◽  
Lin Wang ◽  
Kayla Duval ◽  
Jing Fan ◽  
Shaobing Zhou ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Release ◽  
Tumor Targeting ◽  
Polymeric Micelles

Cytokine-induced killer cells-assisted tumor-targeting delivery of Her-2 monoclonal antibody-conjugated gold nanostars with NIR photosensitizer for enhanced therapy of cancer

2020 ◽  
Vol 8 (36) ◽  
pp. 8368-8382
Author(s):  
Shujing Liang ◽  
Menglin Sun ◽  
Yonglin Lu ◽  
Shuo Shi ◽  
Yiting Yang ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Cancer Therapy ◽  
Multimodal Imaging ◽  
Tumor Targeting ◽  
Killer Cells ◽  
Cik Cells ◽  
Gold Nanostars ◽  
Targeting Delivery ◽  
Her 2

Herein, CIK cells were loaded with GNS@ICG-Ab as an innovative nanoplatform under the guidance of multimodal imaging for synergistic cancer therapy.

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