Functionalization of NaGdF4 nanoparticles with a dibromomaleimide-terminated polymer for MR/optical imaging of thrombosis

2020 ◽  
Vol 11 (5) ◽  
pp. 1010-1017 ◽  
Author(s):  
Yuhuan Li ◽  
Fangyun Xin ◽  
Jinming Hu ◽  
Shweta Jagdale ◽  
Thomas P. Davis ◽  
...  
Keyword(s):  
Molecular Imaging ◽  
Magnetic Resonance ◽  
Optical Imaging ◽  
Dual Modality ◽  
Imaging Probe ◽  
Molecular Imaging Probe ◽  
Targeted Molecular Imaging

A thrombosis-targeted molecular imaging probe with magnetic resonance (MR) and optical dual-modality capacity using dibromomaleimide (DBM)-bearing polymer-grafted NaGdF4 nanoparticles.

CLIC1 antibody conjugated nanoscale contrast agent as a sensitive and targeted molecular imaging probe for gallbladder cancer diagnosis

RSC Advances ◽  
2016 ◽  
Vol 6 (29) ◽  
pp. 24104-24110 ◽  
Author(s):  
Wei Lu ◽  
Ning Wang ◽  
YanYan Chu ◽  
Linzhu Zhou ◽  
Maolan Li ◽  
...  
Keyword(s):  
Molecular Imaging ◽  
Contrast Agent ◽  
Contrast Agents ◽  
Gallbladder Cancer ◽  
Cancer Diagnosis ◽  
Imaging Probe ◽  
Molecular Imaging Probes ◽  
Imaging Probes ◽  
Molecular Imaging Probe ◽  
Targeted Molecular Imaging

CLIC1 antibody-conjugated nano-scale contrast agents exhibit a fast and sensitive detection of gallbladder tumors and may be used in the future as powerful targeted molecular imaging probes for gallbladder cancer diagnosis.

Biosynthetic molecular imaging probe for tumor-targeted dual-modal fluorescence/magnetic resonance imaging

Biomaterials ◽  
2020 ◽  
Vol 256 ◽  
pp. 120220
Author(s):  
Huaixin Zhao ◽  
Huiting Zhao ◽  
Yi Jiao ◽  
Yi Zhu ◽  
Chunxia Liu ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Molecular Imaging ◽  
Magnetic Resonance ◽  
Resonance Imaging ◽  
Imaging Probe ◽  
Molecular Imaging Probe

scholarly journals Development and evaluation of a non-peptidic ligand for the molecular imaging of inflammatory processes using S100A9 (MRP14) as a novel target

2015 ◽  
Vol 51 (86) ◽  
pp. 15637-15640 ◽  
Author(s):  
A. Faust ◽  
T. Völler ◽  
F. Busch ◽  
M. Schäfers ◽  
J. Roth ◽  
...  
Keyword(s):  
Molecular Imaging ◽  
Optical Imaging ◽  
Inflammatory Activity ◽  
Imaging Probe ◽  
Inflammatory Processes ◽  
Molecular Imaging Probe ◽  
Novel Target

We describe the development and first evaluation of a novel S100A9 specific molecular imaging probe (Cy5.5-CES271) for optical imaging of local inflammatory activity in vivo.

scholarly journals Techniques for Molecular Imaging Probe Design

2011 ◽  
Vol 10 (6) ◽  
pp. 7290.2011.00003 ◽  
Author(s):  
Fred Reynolds ◽  
Kimberly A. Kelly
Keyword(s):  
Molecular Imaging ◽  
Target Selection ◽  
Relevant Information ◽  
Probe Design ◽  
Imaging Probe ◽  
Molecular Imaging Probes ◽  
Genomics And Proteomics ◽  
Imaging Probes ◽  
Molecular Imaging Probe ◽  
Underlying Mechanisms

Molecular imaging allows clinicians to visualize disease-specific molecules, thereby providing relevant information in the diagnosis and treatment of patients. With advances in genomics and proteomics and underlying mechanisms of disease pathology, the number of targets identified has significantly outpaced the number of developed molecular imaging probes. There has been a concerted effort to bridge this gap with multidisciplinary efforts in chemistry, proteomics, physics, material science, and biology—all essential to progress in molecular imaging probe development. In this review, we discuss target selection, screening techniques, and probe optimization with the aim of developing clinically relevant molecularly targeted imaging agents.

An in vivo molecular imaging probe 18F-Annexin B1 for apoptosis detection by PET/CT: preparation and preliminary evaluation

APOPTOSIS ◽  
2012 ◽  
Vol 18 (2) ◽  
pp. 238-247 ◽  
Author(s):  
Ming-Wei Wang ◽  
Fang Wang ◽  
Yu-Jia Zheng ◽  
Ying-Jian Zhang ◽  
Yong-Ping Zhang ◽  
...  
Keyword(s):  
Molecular Imaging ◽  
Preliminary Evaluation ◽  
Imaging Probe ◽  
Pet Ct ◽  
Apoptosis Detection ◽  
Molecular Imaging Probe ◽  
Annexin B1

scholarly journals Breast cancer cell targeted MR molecular imaging probe: Anti-MUC1 antibody-based magnetic nanoparticles

2017 ◽  
Vol 851 ◽  
pp. 012014 ◽  
Author(s):  
P Moradi Khaniabadi ◽  
A. M. S.A Majid ◽  
M Asif ◽  
B Moradi Khaniabadi ◽  
D Shahbazi-Gahrouei ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Magnetic Nanoparticles ◽  
Molecular Imaging ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Imaging Probe ◽  
Molecular Imaging Probe

scholarly journals A fluorescent molecular imaging probe with selectivity for soluble tau aggregated protein

2020 ◽  
Vol 11 (18) ◽  
pp. 4773-4778
Author(s):  
Yanyan Zhao ◽  
Ole Tietz ◽  
Wei-Li Kuan ◽  
Abdul K. Haji-Dheere ◽  
Stephen Thompson ◽  
...  
Keyword(s):  
Molecular Imaging ◽  
Neurodegenerative Diseases ◽  
Imaging Probe ◽  
Bold Imaging ◽  
Molecular Imaging Probe

pTP-TFE imaging probe can distinguish soluble tau aggregated proteins from other aggregated proteins enabling earlier detection of neurodegenerative diseases.

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