Paclitaxel-loaded dextran nanoparticles decorated with RVG29 peptide for targeted chemotherapy of glioma: an in vivo study

2020 ◽  
Vol 44 (15) ◽  
pp. 5692-5701
Author(s):  
Hailing Han ◽  
Ying Zhang ◽  
Shunzi Jin ◽  
Ping Chen ◽  
Shi Liu ◽  
...  
Keyword(s):  
In Vivo Study ◽  
Targeted Chemotherapy ◽  
Brain Glioma ◽  
The Brain

The RVG29–dextran–PTX nanoparticles can cross the BBB, reach the brain glioma, and thus improve PTX efficacy.

Experimental in-vivo study of laser-tissue interaction on the brain: influence of gaseous environment

1990 ◽  
Author(s):  
Maria C. Chavantes ◽  
Lucia J. Zamorano ◽  
Federico Vinas ◽  
Manuel Dujovny ◽  
Ljubisa Dragovic
Keyword(s):  
In Vivo Study ◽  
Tissue Interaction ◽  
Gaseous Environment ◽  
Laser Tissue Interaction ◽  
The Brain

l-Threodops increases extracellular norepinephrine levels in the brain: An in vivo study

Neurology ◽  
1990 ◽  
Vol 40 (7) ◽  
pp. 1134-1134 ◽  
Author(s):  
T. Brannan ◽  
A. Bhardwaj ◽  
M. D. Yahr
Keyword(s):  
In Vivo Study ◽  
The Brain

In vivo study of the oxygen tension in the brain tissues during prolonged acceleration

1964 ◽  
Vol 55 (1) ◽  
pp. 37-40
Author(s):  
E. A. Kovalenko ◽  
V. L. Popkov ◽  
I. N. Chernyakov
Keyword(s):  
Oxygen Tension ◽  
In Vivo Study ◽  
The Brain ◽  
Brain Tissues

scholarly journals Non-Invasive In Vivo Study of the Trypanosoma vivax Infectious Process Consolidates the Brain Commitment in Late Infections

2013 ◽  
Vol 7 (1) ◽  
pp. e1976 ◽  
Author(s):  
Simon D'Archivio ◽  
Alain Cosson ◽  
Mathieu Medina ◽  
Thierry Lang ◽  
Paola Minoprio ◽  
...  
Keyword(s):  
In Vivo Study ◽  
Trypanosoma Vivax ◽  
Infectious Process ◽  
Non Invasive ◽  
The Brain

scholarly journals A window into the brain: An in vivo study of the retina in schizophrenia using optical coherence tomography

2012 ◽  
Vol 203 (1) ◽  
pp. 89-94 ◽  
Author(s):  
Elvina May-Yin Chu ◽  
Madhan Kolappan ◽  
Thomas R.E. Barnes ◽  
Eileen M. Joyce ◽  
Maria A. Ron
Keyword(s):  
Optical Coherence Tomography ◽  
In Vivo Study ◽  
Optical Coherence ◽  
The Brain

scholarly journals Anti-cancer Antibody Trastuzumab-Melanotransferrin Conjugate (BT2111) for the Treatment of Metastatic HER2+ Breast Cancer Tumors in the Brain: an In-Vivo Study

2016 ◽  
Vol 33 (12) ◽  
pp. 2930-2942 ◽  
Author(s):  
Mohamed Ismail Nounou ◽  
Chris E. Adkins ◽  
Evelina Rubinchik ◽  
Tori B. Terrell-Hall ◽  
Mohamed Afroz ◽  
...  
Keyword(s):  
Breast Cancer ◽  
In Vivo Study ◽  
Her2 Breast Cancer ◽  
Anti Cancer ◽  
The Brain

Effect of pH and inhibitors on beta-amyloid fibril assembly

1996 ◽  
Vol 54 ◽  
pp. 752-753
Author(s):  
Beverly E. Maleeff ◽  
Timothy K. Hart ◽  
Stephen J. Wood ◽  
Ronald Wetzel
Keyword(s):  
Amyloid Fibril ◽  
Peptide Fragment ◽  
Hydrophobic Peptides ◽  
Amyloid Fibril Formation ◽  
Effects Of Ph ◽  
Severity Of The Disease ◽  
Kinetics Of ◽  
The Brain

Alzheimer's disease is characterized post-mortem in part by abnormal extracellular neuritic plaques found in brain tissue. There appears to be a correlation between the severity of Alzheimer's dementia in vivo and the number of plaques found in particular areas of the brain. These plaques are known to be the deposition sites of fibrils of the protein β-amyloid. It is thought that if the assembly of these plaques could be inhibited, the severity of the disease would be decreased. The peptide fragment Aβ, a precursor of the p-amyloid protein, has a 40 amino acid sequence, and has been shown to be toxic to neuronal cells in culture after an aging process of several days. This toxicity corresponds to the kinetics of in vitro amyloid fibril formation. In this study, we report the biochemical and ultrastructural effects of pH and the inhibitory agent hexadecyl-N-methylpiperidinium (HMP) bromide, one of a class of ionic micellar detergents known to be capable of solubilizing hydrophobic peptides, on the in vitro assembly of the peptide fragment Aβ.

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