scholarly journals Programmed supramolecular nanoassemblies: enhanced serum stability and cell specific triggered release of anti-cancer drugs

2019 ◽  
Vol 1 (4) ◽  
pp. 1571-1580 ◽  
Author(s):  
Sanchaita Mondal ◽  
Moumita Saha ◽  
Mousumi Ghosh ◽  
Subrata Santra ◽  
Mijan A. Khan ◽  
...  

A bolaamphiphilic cross-linked nanoassembly endowed with pH responsive degradation features has been designed and fabricated for stable noncovalent guest encapsulation and controlled release.

RSC Advances ◽  
2015 ◽  
Vol 5 (60) ◽  
pp. 48586-48595 ◽  
Author(s):  
Ali Pourjavadi ◽  
Zahra Mazaheri Tehrani ◽  
Seyed Hassan Hosseini

In the present study, we designed a pH-responsive drug nanocarrier based on polyamidoamine-modified Fe3O4 nanoparticles coated by PEGylated starch-co-poly(acrylic acid).


RSC Advances ◽  
2014 ◽  
Vol 4 (46) ◽  
pp. 24232-24239 ◽  
Author(s):  
Xubo Zhao ◽  
Peng Liu

A novel graphene oxide (GO)-based nanocarrier has been designed for the targeting and pH-responsive controlled release of anti-cancer drugs.


Nanoscale ◽  
2018 ◽  
Vol 10 (20) ◽  
pp. 9773-9779 ◽  
Author(s):  
Devleena Samanta ◽  
Niloufar Hosseini-Nassab ◽  
Aidan D. McCarty ◽  
Richard N. Zare

Redox-active anti-cancer drugs can be released without compromising their bioactivity from polypyrrole nanoparticles that respond to ultra-low voltages (−75 mV).


Author(s):  
Shekhar Verma ◽  
Nagendra Chandrawanshi ◽  
Vishal Jain

Around 40% of new chemical entities and drugs are lipophilic or poor aqueous soluble in nature. Among them many anti-cancer drugs are also consist lipophilic properties. Available poorly water soluble anti-cancer drugs are paclitaxel, etoposide, and docetaxel. To get better stability of those anti-cancer drug via encapsulation and searching suitable carrier system for the controlled release, design and development requires of anhydrous nano carrier system. However, to deliver and entrapment of these kind of anti-cancer drugs are very essential with avoidance of water free preparation to get suitable controlled release application and achieve targeting site. The primary objective of proposed chapter is to develop and design novel stable anhydrous or non-aqueous nano emulsion carrier system and provide suitable carrier system for poorly aqueous soluble anti-cancer drugs. Another important aim is to design and develop better stabilizing agent by combining different type of surfactant, co-surfactant, and co-solvent.


2017 ◽  
Vol 13 (12) ◽  
pp. 1647-1659 ◽  
Author(s):  
Jun Cao ◽  
Haoran Zheng ◽  
Rui Hu ◽  
Jianhong Liao ◽  
Zengming Fei ◽  
...  

RSC Advances ◽  
2015 ◽  
Vol 5 (22) ◽  
pp. 17041-17041 ◽  
Author(s):  
Xubo Zhao ◽  
Peng Liu

Correction for ‘Biocompatible graphene oxide as a folate receptor-targeting drug delivery system for the controlled release of anti-cancer drugs’ by Xubo Zhao et al., RSC Adv., 2014, 4, 24232–24239.


2015 ◽  
Vol 357 ◽  
pp. 2077-2086 ◽  
Author(s):  
Congli Wang ◽  
Lizhen Huang ◽  
Shengmei Song ◽  
Bassam Saif ◽  
Yehong Zhou ◽  
...  

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