Targeted delivery and pH-responsive release of stereoisomeric anti-cancer drugs using β-cyclodextrin assemblied Fe3O4 nanoparticles

2015 ◽  
Vol 357 ◽  
pp. 2077-2086 ◽  
Author(s):  
Congli Wang ◽  
Lizhen Huang ◽  
Shengmei Song ◽  
Bassam Saif ◽  
Yehong Zhou ◽  
...  
Keyword(s):  
Fe3o4 Nanoparticles ◽  
Targeted Delivery ◽  
Cancer Drugs ◽  
Ph Responsive ◽  
Anti Cancer

scholarly journals pH responsive glycopolymer nanoparticles for targeted delivery of anti-cancer drugs

2018 ◽  
Vol 3 (1) ◽  
pp. 150-158 ◽  
Author(s):  
Gokhan Yilmaz ◽  
Emine Guler ◽  
Caner Geyik ◽  
Bilal Demir ◽  
Melek Ozkan ◽  
...  
Keyword(s):  
Targeted Delivery ◽  
Cancer Drugs ◽  
Ph Responsive ◽  
The Past ◽  
Anti Cancer

Over the past decade, there has been a great deal of interest in the integration of nanotechnology and carbohydrates.

Dendritic magnetite decorated by pH-responsive PEGylated starch: a smart multifunctional nanocarrier for the triggered release of anti-cancer drugs

RSC Advances ◽  
2015 ◽  
Vol 5 (60) ◽  
pp. 48586-48595 ◽  
Author(s):  
Ali Pourjavadi ◽  
Zahra Mazaheri Tehrani ◽  
Seyed Hassan Hosseini
Keyword(s):  
Acrylic Acid ◽  
Cancer Drugs ◽  
Ph Responsive ◽  
Triggered Release ◽  
Anti Cancer ◽  
Poly Acrylic Acid

In the present study, we designed a pH-responsive drug nanocarrier based on polyamidoamine-modified Fe3O4 nanoparticles coated by PEGylated starch-co-poly(acrylic acid).

pH-Responsive Nanoparticles Based on Covalently Grafted Conjugates of Carboxymethyl Chitosan and Daunorubicin for the Delivery of Anti-Cancer Drugs

2017 ◽  
Vol 13 (12) ◽  
pp. 1647-1659 ◽  
Author(s):  
Jun Cao ◽  
Haoran Zheng ◽  
Rui Hu ◽  
Jianhong Liao ◽  
Zengming Fei ◽  
...  
Keyword(s):  
Carboxymethyl Chitosan ◽  
Cancer Drugs ◽  
Ph Responsive ◽  
Anti Cancer

Biocompatible graphene oxide as a folate receptor-targeting drug delivery system for the controlled release of anti-cancer drugs

RSC Advances ◽  
2014 ◽  
Vol 4 (46) ◽  
pp. 24232-24239 ◽  
Author(s):  
Xubo Zhao ◽  
Peng Liu
Keyword(s):  
Drug Delivery ◽  
Graphene Oxide ◽  
Controlled Release ◽  
Drug Delivery System ◽  
Delivery System ◽  
Folate Receptor ◽  
Cancer Drugs ◽  
Ph Responsive ◽  
Anti Cancer ◽  
Folate Receptor Targeting

A novel graphene oxide (GO)-based nanocarrier has been designed for the targeting and pH-responsive controlled release of anti-cancer drugs.

scholarly journals Graphene oxide loaded with tumor-targeted peptide and anti-cancer drugs for cancer target therapy

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Ran Li ◽  
Yimei Wang ◽  
Jie Du ◽  
Xiangyu Wang ◽  
Ailin Duan ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Targeted Delivery ◽  
Tumor Targeting ◽  
Target Therapy ◽  
Ph Responsive ◽  
Chemotherapy Drugs ◽  
Tumor Tissues ◽  
Anti Cancer ◽  
Good Technique ◽  
Nanoparticle System

AbstractIn the present work, we constructed nanoscale graphene oxide (NGO) as a drug nanocarrier to improve the process of tumor-targeted drug releases, promote cellular uptake and accumulation of chemotherapy drugs in tumor tissues, and reduce the toxic effects of chemotherapy drugs on normal cells. Hence, great stability was obtained in the biological solution. Moreover, we designed an effective nanoparticle system for the doxorubicin (DOX) delivery targeting the oral squamous cell carcinoma (OSCC) by mediating the HN-1 (TSPLNIHNGQKL) through hydrogen and π–π bonds. DOX@NGO-PEG-HN-1 showed significantly higher cellular uptakes and cytotoxicity in OSCC cells (CAL-27 and SCC-25), compared to free DOX. Moreover, HN-1 showed considerable tumor-targeting and competition inhibition phenomenon. As we expected, the nanocarrier showed pH-responsive drug release. In total, our study represented a good technique to construct OSCC-targeted delivery of nanoparticles and improve the anticancer medicines’ efficiency.

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