scholarly journals Mass-producible microporous silicon membranes for specific leukocyte subset isolation, immunophenotyping, and personalized immunomodulatory drug screening in vitro

Lab on a Chip ◽  
2019 ◽  
Vol 19 (18) ◽  
pp. 3065-3076 ◽  
Author(s):  
Andrew Stephens ◽  
Robert Nidetz ◽  
Nicolas Mesyngier ◽  
Meng Ting Chung ◽  
Yujing Song ◽  
...  
Keyword(s):  
Microfluidic Device ◽  
Drug Screening ◽  
Leukocyte Subset ◽  
Immunomodulatory Drug ◽  
Silicon Membranes ◽  
On Chip ◽  
Leukocyte Populations ◽  
Screening In Vitro

Si micromachining processes were used to create a mass-producible immunophenotyping microfluidic device which can isolate and stimulate specific leukocyte populations, enabling measurement of secreted cytokines on-chip via a no-wash immunoassay.

scholarly journals Achievement of constitutive fluorescent pLEXSY-egfp Leishmania braziliensis and its application as an alternative method for drug screening in vitro

2017 ◽  
Vol 112 (2) ◽  
pp. 155-159 ◽  
Author(s):  
Matheus Silva e Bastos ◽  
◽  
Luciana Ângelo de Souza ◽  
Thiago Souza Onofre ◽  
Abelardo Silva Júnior ◽  
...  
Keyword(s):  
Drug Screening ◽  
Leishmania Braziliensis ◽  
Alternative Method ◽  
Screening In Vitro

Substrate stiffness influences the outcome of antitumor drug screening in vitro

2013 ◽  
Vol 55 (1) ◽  
pp. 121-131 ◽  
Author(s):  
Jiantao Feng ◽  
Yong Tang ◽  
Yonggang Xu ◽  
Quanmei Sun ◽  
Fulong Liao ◽  
...  
Keyword(s):  
Drug Screening ◽  
Antitumor Drug ◽  
Substrate Stiffness ◽  
Screening In Vitro

scholarly journals On-chip automation of cell-free protein synthesis: new opportunities due to a novel reaction mode

Lab on a Chip ◽  
2016 ◽  
Vol 16 (2) ◽  
pp. 269-281 ◽  
Author(s):  
V. Georgi ◽  
L. Georgi ◽  
M. Blechert ◽  
M. Bergmeister ◽  
M. Zwanzig ◽  
...  
Keyword(s):  
Protein Synthesis ◽  
Microfluidic Device ◽  
Free Protein ◽  
On Chip ◽  
Cell Free Protein Synthesis

The microfluidic device for cell-free protein synthesis enables a novel reaction mode with continuous in vitro transcription and translation in separate compartments combined by magnetic and microfluidic actuated mRNA transfer.

Toxoplasma gondii: A simple high-throughput assay for drug screening in vitro

2009 ◽  
Vol 121 (2) ◽  
pp. 132-136 ◽  
Author(s):  
ChunMei Jin ◽  
Kusuma Kaewintajuk ◽  
JingHua Jiang ◽  
WooJin Jeong ◽  
Masaki Kamata ◽  
...  
Keyword(s):  
Toxoplasma Gondii ◽  
High Throughput ◽  
Drug Screening ◽  
High Throughput Assay ◽  
Screening In Vitro

scholarly journals Beating organs-on-chip as technological platforms in drug screening: Advanced in vitro models of human physiology and pathology

2021 ◽  
Vol 4 (s1) ◽  
Author(s):  
Paola Occhetta ◽  
Roberta Visone ◽  
Stefano Piazza ◽  
Ferran Lozano ◽  
Marco Rasponi
Keyword(s):  
Human Physiology ◽  
Drug Screening ◽  
In Vitro Models ◽  
Human Organs ◽  
On Chip ◽  
Technological Platforms ◽  
Mechanical Microenvironment

Taking advantages of uBeat® technology, 3D beating Organs-on-Chip integrates the native complexity of human mechanical microenvironment into clinically relevant in vitro models of human organs and diseases.

scholarly journals Acanthamoeba castellanii : A new high-throughput method for drug screening in vitro

Acta Tropica ◽  
2016 ◽  
Vol 164 ◽  
pp. 95-99 ◽  
Author(s):  
Antonio Ortega-Rivas ◽  
José M. Padrón ◽  
Basilio Valladares ◽  
Hany M. Elsheikha
Keyword(s):  
High Throughput ◽  
Drug Screening ◽  
Acanthamoeba Castellanii ◽  
High Throughput Method ◽  
Screening In Vitro

Simple and sensitive antimalarial drug screening in vitro and in vivo using transgenic luciferase expressing Plasmodium berghei parasites

2008 ◽  
Vol 38 (14) ◽  
pp. 1651-1662 ◽  
Author(s):  
B. Franke-Fayard ◽  
D. Djokovic ◽  
M.W. Dooren ◽  
J. Ramesar ◽  
A.P. Waters ◽  
...  
Keyword(s):  
Drug Screening ◽  
Plasmodium Berghei ◽  
Antimalarial Drug ◽  
Screening In Vitro
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