Lactic acid bacteria alleviate polycystic ovarian syndrome by regulating sex hormone related gut microbiota

2020 ◽  
Vol 11 (6) ◽  
pp. 5192-5204 ◽  
Author(s):  
Yufeng He ◽  
Qianqian Wang ◽  
Xiu Li ◽  
Gang Wang ◽  
Jianxin Zhao ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Lactic Acid Bacteria ◽  
Gut Microbiota ◽  
Rat Model ◽  
Polycystic Ovarian Syndrome ◽  
Sex Hormone ◽  
Ovarian Syndrome

Administration of certain lactic acid bacteria alleviate polycystic ovarian syndrome in a letrozole induced rat model.

scholarly journals Correction: Lactic acid bacteria alleviate polycystic ovarian syndrome by regulating sex hormone related gut microbiota

2021 ◽  
Author(s):  
Yufeng He ◽  
Qianqian Wang ◽  
Xiu Li ◽  
Gang Wang ◽  
Jianxin Zhao ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Lactic Acid Bacteria ◽  
Gut Microbiota ◽  
Polycystic Ovarian Syndrome ◽  
Sex Hormone ◽  
Ovarian Syndrome

Correction for ‘Lactic acid bacteria alleviate polycystic ovarian syndrome by regulating sex hormone related gut microbiota’ by Yufeng He et al., Food Funct., 2020, 11, 5192–5204, DOI: 10.1039/C9FO02554E.

Inhibitory Effects of Fermented Ougan (Citrus reticulata cv. Suavissima) Juice on High-Fat Diet-induced Obesity Associated with White Adipose Tissue Browning and Gut Microbiota Modulation in Mice

2021 ◽  
Author(s):  
Xiao Guo ◽  
Xuedan Cao ◽  
Xiugui Fang ◽  
Ailing Guo ◽  
Erhu Li
Keyword(s):  
Adipose Tissue ◽  
Lactic Acid ◽  
Lactic Acid Bacteria ◽  
Gut Microbiota ◽  
High Fat Diet ◽  
Citrus Reticulata ◽  
Inhibitory Effects ◽  
High Fat ◽  
Diet Induced Obesity ◽  
Tissue Browning

In this study, Ougan juice (OJ) and lactic acid bacteria fermented Ougan juice (FOJ) were investigated individually for their capability of preventing obesity in high-fat diet (HFD)-fed C57BL/6J mice. After...

Anti-obesity effects of gut microbiota are associated with lactic acid bacteria

2013 ◽  
Vol 98 (1) ◽  
pp. 1-10 ◽  
Author(s):  
Yueh-Ting Tsai ◽  
Po-Ching Cheng ◽  
Tzu-Ming Pan
Keyword(s):  
Lactic Acid ◽  
Lactic Acid Bacteria ◽  
Gut Microbiota

scholarly journals Bak Foong pills combined with metformin in the treatment of a polycystic ovarian syndrome rat model

2015 ◽  
Vol 10 (3) ◽  
pp. 1819-1825 ◽  
Author(s):  
WENHUI LIU ◽  
WENPEI LIU ◽  
YULING FU ◽  
YAN WANG ◽  
YUANZHEN ZHANG
Keyword(s):  
Rat Model ◽  
Polycystic Ovarian Syndrome ◽  
Ovarian Syndrome

scholarly journals Liraglutide Improves Hypertension and Metabolic Perturbation in a Rat Model of Polycystic Ovarian Syndrome

PLoS ONE ◽  
2015 ◽  
Vol 10 (5) ◽  
pp. e0126119 ◽  
Author(s):  
Vanessa Hoang ◽  
Jiangjiang Bi ◽  
Sheba M. Mohankumar ◽  
Arpita K. Vyas
Keyword(s):  
Rat Model ◽  
Polycystic Ovarian Syndrome ◽  
Metabolic Perturbation ◽  
Ovarian Syndrome

Microbiota and epigenetic regulation of inflammatory mediators in type 2 diabetes and obesity

2014 ◽  
Vol 5 (1) ◽  
pp. 33-43 ◽  
Author(s):  
M. Remely ◽  
E. Aumueller ◽  
D. Jahn ◽  
B. Hippe ◽  
H. Brath ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Lactic Acid ◽  
Lactic Acid Bacteria ◽  
Gut Microbiota ◽  
Epigenetic Regulation ◽  
Control Group ◽  
Low Grade ◽  
Type 2 Diabetics ◽  
Significant Difference

Metabolic syndrome is associated with alterations in the structure of the gut microbiota leading to low-grade inflammatory responses. An increased penetration of the impaired gut membrane by bacterial components is believed to induce this inflammation, possibly involving epigenetic alteration of inflammatory molecules such as Toll-like receptors (TLRs). We evaluated changes of the gut microbiota and epigenetic DNA methylation of TLR2 and TLR4 in three groups of subjects: type 2 diabetics under glucagon-like peptide-1 agonist therapy, obese individuals without established insulin resistance, and a lean control group. Clostridium cluster IV, Clostridium cluster XIVa, lactic acid bacteria, Faecalibacterium prausnitzii and Bacteroidetes abundances were analysed by PCR and 454 high-throughput sequencing. The epigenetic methylation in the regulatory region of TLR4 and TLR2 was analysed using bisulfite conversion and pyrosequencing. We observed a significantly higher ratio of Firmicutes/ Bacteroidetes in type 2 diabetics compared to lean controls and obese. Major differences were shown in lactic acid bacteria, with the highest abundance in type 2 diabetics, followed by obese and lean participants. In comparison, F. prausnitzii was least abundant in type 2 diabetics, and most abundant in lean controls. Methylation analysis of four CpGs in the first exon of TLR4 showed significantly lower methylation in obese individuals, but no significant difference between type 2 diabetics and lean controls. Methylation of seven CpGs in the promoter region of TLR2 was significantly lower in type 2 diabetics compared to obese subjects and lean controls. The methylation levels of both TLRs were significantly correlated with body mass index. Our data suggest that changes in gut microbiota and thus cell wall components are involved in the epigenetic regulation of inflammatory reactions. An improved diet targeted to induce gut microbial balance and in the following even epigenetic changes of pro-inflammatory genes may be effective in the prevention of metabolic syndrome.

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