Towards capturing cellular complexity: combining encapsulation and macromolecular crowding in a reverse micelle

2019 ◽  
Vol 21 (15) ◽  
pp. 8108-8120 ◽  
Author(s):  
Philipp Honegger ◽  
Othmar Steinhauser

This paper studies the orientational structure and dynamics of multi-protein systems under confinement and discusses the implications on biological cells.

FEBS Journal ◽  
2020 ◽  
Vol 287 (23) ◽  
pp. 5039-5067 ◽  
Author(s):  
Maryna Löwe ◽  
Milara Kalacheva ◽  
Arnold J. Boersma ◽  
Alexej Kedrov

2016 ◽  
Vol 648 ◽  
pp. 130-136 ◽  
Author(s):  
Siddharth Gautam ◽  
Tingting Liu ◽  
Sumant Patankar ◽  
David Tomasko ◽  
David Cole

2018 ◽  
Vol 20 (29) ◽  
pp. 19581-19594 ◽  
Author(s):  
Philipp Honegger ◽  
Michael Schmollngruber ◽  
Othmar Steinhauser

Extensive computational studies of ubiquitin crowding with a special focus on protein hydration directly visible in dielectric spectra.


2017 ◽  
Vol 147 (11) ◽  
pp. 114902 ◽  
Author(s):  
Swomitra Palit ◽  
Lilin He ◽  
William A. Hamilton ◽  
Arun Yethiraj ◽  
Anand Yethiraj

2006 ◽  
Vol 73 ◽  
pp. 109-119 ◽  
Author(s):  
Chris Stockdale ◽  
Michael Bruno ◽  
Helder Ferreira ◽  
Elisa Garcia-Wilson ◽  
Nicola Wiechens ◽  
...  

In the 30 years since the discovery of the nucleosome, our picture of it has come into sharp focus. The recent high-resolution structures have provided a wealth of insight into the function of the nucleosome, but they are inherently static. Our current knowledge of how nucleosomes can be reconfigured dynamically is at a much earlier stage. Here, recent advances in the understanding of chromatin structure and dynamics are highlighted. The ways in which different modes of nucleosome reconfiguration are likely to influence each other are discussed, and some of the factors likely to regulate the dynamic properties of nucleosomes are considered.


1998 ◽  
Vol 77 (2) ◽  
pp. 357-362 ◽  
Author(s):  
A. Matic, L. Borjesson

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