Peptide-templated gold nanoparticle nanosensor for simultaneous detection of multiple posttranslational modification enzymes

2020 ◽  
Vol 56 (2) ◽  
pp. 213-216 ◽  
Author(s):  
Dandan Zhang ◽  
Ya-ru Meng ◽  
Chun-yang Zhang

We developed a peptide-templated gold nanoparticle (AuNP) nanosensor for simultaneous detection of multiple posttranslational modification (PTM) enzymes.

2021 ◽  
Vol 7 (8) ◽  
pp. eabe3610
Author(s):  
Conor J. Kearney ◽  
Stephin J. Vervoort ◽  
Kelly M. Ramsbottom ◽  
Izabela Todorovski ◽  
Emily J. Lelliott ◽  
...  

Multimodal single-cell RNA sequencing enables the precise mapping of transcriptional and phenotypic features of cellular differentiation states but does not allow for simultaneous integration of critical posttranslational modification data. Here, we describe SUrface-protein Glycan And RNA-seq (SUGAR-seq), a method that enables detection and analysis of N-linked glycosylation, extracellular epitopes, and the transcriptome at the single-cell level. Integrated SUGAR-seq and glycoproteome analysis identified tumor-infiltrating T cells with unique surface glycan properties that report their epigenetic and functional state.


RSC Advances ◽  
2014 ◽  
Vol 4 (52) ◽  
pp. 27625 ◽  
Author(s):  
Haofan Sun ◽  
Jie Chao ◽  
Xiaolei Zuo ◽  
Shao Su ◽  
Xingfen Liu ◽  
...  

The Analyst ◽  
2021 ◽  
Author(s):  
Jingjing Yao ◽  
Xin-Xin Xu ◽  
Liqiang Liu ◽  
Hua Kuang ◽  
Zhengyou Wang ◽  
...  

We have developed a sensitive and rapid gold nanoparticle-based immunochromatographic strip (GNP-ICS) for the detection of phenacetin (PNCT) using an anti-PNCT monoclonal antibody (mAb). The specific anti- PNCT mAb (2D6)...


Small ◽  
2017 ◽  
Vol 14 (6) ◽  
pp. 1701782 ◽  
Author(s):  
Lingling Guo ◽  
Xiaoling Wu ◽  
Liqiang Liu ◽  
Hua Kuang ◽  
Chuanlai Xu

RSC Advances ◽  
2015 ◽  
Vol 5 (115) ◽  
pp. 95028-95037 ◽  
Author(s):  
Balwinder Kaur ◽  
Rajendra Srivastava ◽  
Biswarup Satpati

High electrocatalytic activity of the sensor can be attributed to the highly dispersed gold nanoparticles on the nanocrystalline zeolite matrix.


2018 ◽  
Vol 2 (10) ◽  
pp. 1900-1910 ◽  
Author(s):  
Zhongxing Wang ◽  
Li Sun ◽  
Liqiang Liu ◽  
Hua Kuang ◽  
Liguang Xu ◽  
...  

We developed an ultrasensitive gold nanoparticle-based multicomponent lateral-flow strip assay for the simultaneous detection of seventeen hormone drugs from three classes: nandrolone (NR) and its analogues, dexamethasone (DEX) and its analogues, and hexestrol (HES) and its analogues.


2019 ◽  
Vol 43 (42) ◽  
pp. 16572-16582 ◽  
Author(s):  
Anuja S. Rajpurohit ◽  
Ninad S. Punde ◽  
Ashwini K. Srivastava

Highly sensitive electro-oxidation of the MGO and GLO biomarkers at the CuO/Au/GCE sensor employing the AdSDPV method.


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