Stereoselective synthesis of 2,5-disubstituted pyrrolidines via gold-catalysed anti-Markovnikov hydroamination-initiated tandem reactions

2019 ◽  
Vol 55 (67) ◽  
pp. 9923-9926 ◽  
Author(s):  
Tong-De Tan ◽  
Yang-Bo Chen ◽  
Ming-Yang Yang ◽  
Jia-Le Wang ◽  
Hao-Ze Su ◽  
...  

A series of gold-catalyzed intramolecular hydroamination-initiated azidation, allylation and heteroarylation reactions enable the rapid construction of enantioenriched 2,5-disubstituted pyrrolidines.

ChemInform ◽  
2010 ◽  
Vol 33 (15) ◽  
pp. no-no
Author(s):  
Hitoshi Akiyama ◽  
Tetsuya Fujimoto ◽  
Katsuyoshi Ohshima ◽  
Kenji Hoshino ◽  
Yuko Saito ◽  
...  

2016 ◽  
Vol 52 (5) ◽  
pp. 912-915 ◽  
Author(s):  
Chao-Yang Lin ◽  
Peng-Ju Ma ◽  
Zhao Sun ◽  
Chong-Dao Lu ◽  
Yan-Jun Xu

A carbamoyl anion-initiated cascade reaction with acylsilanes and imines allows rapid construction of substituted α-hydroxy-β-amino amides in high yields with excellent diastereoselectivities.


2016 ◽  
Vol 18 (6) ◽  
pp. 1382-1385 ◽  
Author(s):  
Hong-Ru Wu ◽  
Liang Cheng ◽  
De-Long Kong ◽  
Hong-Yan Huang ◽  
Chun-Ling Gu ◽  
...  

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