A cucurbituril/polysaccharide/carbazole ternary supramolecular assembly for targeted cell imaging

2019 ◽  
Vol 55 (30) ◽  
pp. 4343-4346 ◽  
Author(s):  
Xuan Wu ◽  
Yong Chen ◽  
Qilin Yu ◽  
Feng-Qing Li ◽  
Yu Liu
Keyword(s):  
Photodynamic Therapy ◽  
Near Infrared ◽  
Cell Imaging ◽  
Supramolecular Assembly ◽  
Targeted Photodynamic Therapy

A ternary supramolecular assembly with near-infrared lysosome imaging and targeted photodynamic therapy properties was successfully orthogonally constructed in a two-step assembly manner.

Near-infrared-emitting AIE multinuclear cationic Ir(iii) complex-assembled nanoparticles for photodynamic therapy

2020 ◽  
Vol 49 (43) ◽  
pp. 15332-15338
Author(s):  
Lijuan Li ◽  
Liping Zhang ◽  
Xiaofan Tong ◽  
Yite Li ◽  
Zhiyu Yang ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Self Assembly ◽  
Near Infrared ◽  
Cell Imaging

The first pure NIR-emitting AIE multinuclear Ir(iii) complex NPs obtained by self-assembly exhibit excellent cell imaging and PDT performance.

scholarly journals Cancer-mitochondria-targeted photodynamic therapy with supramolecular assembly of HA and a water soluble NIR cyanine dye

2017 ◽  
Vol 8 (12) ◽  
pp. 8351-8356 ◽  
Author(s):  
Ajesh P. Thomas ◽  
L. Palanikumar ◽  
M. T. Jeena ◽  
Kibeom Kim ◽  
Ja-Hyoung Ryu
Keyword(s):  
Photodynamic Therapy ◽  
Supramolecular Assembly ◽  
Water Soluble ◽  
Cyanine Dye ◽  
Targeted Photodynamic Therapy

Herein, we introduce an indocyanine derivative (IR-Pyr) that is highly water soluble, exhibiting higher mitochondrial targetability and better photostability than IR-780.

Functionalized diphenylchlorins and bacteriochlorins: their synthesis and bioconjugation for targeted photodynamic therapy and tumour cell imaging

2000 ◽  
Vol 04 (07) ◽  
pp. 655-658 ◽  
Author(s):  
JONATHAN M. SUTTON ◽  
NELSON FERNANDEZ ◽  
ROSS W. BOYLE
Keyword(s):  
Photodynamic Therapy ◽  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Tumour Cell ◽  
Bovine Serum ◽  
Osmium Tetroxide ◽  
Cell Imaging ◽  
Important Group ◽  
Structure Activity ◽  
Targeted Photodynamic Therapy

A range of 5,15-diphenylporphyrins with symmetric and unsymmetric substitution patterns were subjected to osmium tetroxide-mediated dihydroxylations. The resulting chlorins and bacteriochlorins present an important group of compounds for studying structure-activity relationships of photodynamic sensitizers. The regioselectivity of the dihydroxylation of various 5,15-diphenylporphyrins with unsymmetrical substitution patterns was also examined. Both diphenylchlorin diol (DPC) and diphenylbacteriochlorin tetrol (DPBC) examples were converted into reactive isothiocyanates and conjugated with bovine serum albumin (BSA).

A new near-infrared phosphorescent iridium(III) complex conjugated to an xanthene dye for mitochondria-targeted photodynamic therapy

2021 ◽  
Author(s):  
Yongquan Wu ◽  
Jie Wu ◽  
Wai-Yeung Raymond Wong
Keyword(s):  
Photodynamic Therapy ◽  
Near Infrared ◽  
Clinical Translation ◽  
Targeted Photodynamic Therapy

Iridium(III) complexes are potent candidates for photodynamic therapy (PDT), but some key drawbacks still hamper clinical translation, such as poor operability in the phototherapeutic window, high dark toxicity, and low...

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