A lysosome-targeting dual-functional fluorescent probe for imaging intracellular viscosity and beta-amyloid

2019 ◽  
Vol 55 (18) ◽  
pp. 2688-2691 ◽  
Author(s):  
Hui-ya Tan ◽  
Yu-tai Qiu ◽  
Han Sun ◽  
Jin-wu Yan ◽  
Lei Zhang
Keyword(s):  
Fluorescent Probe ◽  
Beta Amyloid ◽  
Dual Functional ◽  
Amyloid P

A lysosome-targeting dual-functional fluorescent probe was rationally designed and developed for imaging intracellular lysosomal viscosity and beta-amyloid.

A Novel Dual-functional Fluorescent Probe for Imaging Viscosity and Cysteine in Living System

2021 ◽  
Author(s):  
Manlin Fu ◽  
Kai Wang ◽  
Qiancheng Ma ◽  
Mianli Bian ◽  
Qing Zhu
Keyword(s):  
Fluorescent Probe ◽  
Redox Reaction ◽  
Living System ◽  
Pivotal Role ◽  
Biological Processes ◽  
Dual Functional ◽  
Reversible Redox

Abnormal changes in intracellular viscosity and cysteine are both associated with several important biological processes such as reversible redox reaction, which plays a pivotal role in the process of inflammation....

A Dual Functional Electroactive and Fluorescent Probe for Coupled Measurements of Vesicular Exocytosis with High Spatial and Temporal Resolution

2017 ◽  
Vol 129 (9) ◽  
pp. 2406-2410 ◽  
Author(s):  
Xiaoqing Liu ◽  
Alexandra Savy ◽  
Sylvie Maurin ◽  
Laurence Grimaud ◽  
François Darchen ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Temporal Resolution ◽  
Dual Functional ◽  
Vesicular Exocytosis

Nopinone-based AIE-active dual-functional fluorescent chemosensor for Hg2+ and Cu2+ and its environmental and biological applications

2020 ◽  
Vol 49 (43) ◽  
pp. 15299-15309
Author(s):  
Mingxin Li ◽  
Shutang Ruan ◽  
Haiyan Yang ◽  
Yan Zhang ◽  
Yiqin Yang ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Environmental Analysis ◽  
Fluorescent Chemosensor ◽  
Biological Applications ◽  
Dual Functional

A nopinone-based dual-functional fluorescent probe for Hg2+ and Cu2+ and its applications in environmental analysis and bioimaging.

A dual functional fluorogenic probe for visualization of intracellular pH and formaldehyde with distinct fluorescence signals

2018 ◽  
Vol 16 (25) ◽  
pp. 4628-4632 ◽  
Author(s):  
Zhenda Xie ◽  
Biao Yin ◽  
Jiajie Shen ◽  
Danqi Hong ◽  
Liquan Zhu ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Intracellular Ph ◽  
Dual Functional ◽  
Fluorogenic Probe

We present a dual functional fluorescent probe (DPFP) for imaging pH and formaldehyde (FA) with distinct fluorescence signals.

Amphiphilic dendrons with a pyrene functional group at the focal point: synthesis, self-assembly and generation-dependent DNA condensation

2017 ◽  
Vol 8 (33) ◽  
pp. 4798-4804 ◽  
Author(s):  
Yi Han ◽  
Bo Zhu ◽  
Ying Chen ◽  
Zhishan Bo ◽  
Yulan Chen
Keyword(s):  
Fluorescent Probe ◽  
Self Assembly ◽  
Functional Group ◽  
Focal Point ◽  
Dna Condensation ◽  
Dual Functional

Dendritic amphiphiles with a dual-functional pyrene as a fluorescent probe and hydrophobe at the focal point exhibited generation-dependent self-assembly and DNA condensation.

Testing Aβ toxicity on primary CNS cultures using drug-screening microfluidic chips

Lab on a Chip ◽  
2014 ◽  
Vol 14 (15) ◽  
pp. 2860-2866 ◽  
Author(s):  
A. Ruiz ◽  
P. Joshi ◽  
R. Mastrangelo ◽  
M. Francolini ◽  
C. Verderio ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Drug Screening ◽  
Primary Cultures ◽  
Beta Amyloid ◽  
Microfluidic Chips ◽  
Neuronal Viability ◽  
The Central Nervous System ◽  
Amyloid P ◽  
Neuroprotective Action

Neuronal viability tests performed in primary cultures and co-cultures of the central nervous system grown on microfluidic drug screening chips show a neuroprotective action of FTY720 in cultures degenerated by oligomeric beta amyloid.

A Dual Functional Electroactive and Fluorescent Probe for Coupled Measurements of Vesicular Exocytosis with High Spatial and Temporal Resolution

2017 ◽  
Vol 56 (9) ◽  
pp. 2366-2370 ◽  
Author(s):  
Xiaoqing Liu ◽  
Alexandra Savy ◽  
Sylvie Maurin ◽  
Laurence Grimaud ◽  
François Darchen ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Temporal Resolution ◽  
Dual Functional ◽  
Vesicular Exocytosis
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