A dual functional fluorogenic probe for visualization of intracellular pH and formaldehyde with distinct fluorescence signals

2018 ◽  
Vol 16 (25) ◽  
pp. 4628-4632 ◽  
Author(s):  
Zhenda Xie ◽  
Biao Yin ◽  
Jiajie Shen ◽  
Danqi Hong ◽  
Liquan Zhu ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Intracellular Ph ◽  
Dual Functional ◽  
Fluorogenic Probe

We present a dual functional fluorescent probe (DPFP) for imaging pH and formaldehyde (FA) with distinct fluorescence signals.

Construction of Polysiloxane-Based Fluorescent Probe for Visualizing The pH Down-regulation

2021 ◽  
Author(s):  
Xiaoni Wang ◽  
Zhiming Gou ◽  
Minggang Tian ◽  
Yujing Zuo
Keyword(s):  
Fluorescent Probe ◽  
Intracellular Ph ◽  
Cell Apoptosis ◽  
Pathological Process ◽  
Down Regulation ◽  
Ph Values

Intracellular pH values change is a significant physiological and pathological process and plays vital roles in autophagy, self-repairing, and programmed cell apoptosis. A unique fluorescent probe (PN-1) based on polysiloxanes...

Light-activated “cycle-reversible intramolecular charge transfer” fluorescent probe: monitoring of pHi trace change induced by UV light in programmed cell death

2019 ◽  
Vol 55 (36) ◽  
pp. 5279-5282 ◽  
Author(s):  
Tao Jiang ◽  
Xin Wang ◽  
Ge Wang ◽  
Yafu Wang ◽  
Kui Wang ◽  
...  
Keyword(s):  
Cell Death ◽  
Charge Transfer ◽  
Programmed Cell Death ◽  
Synergistic Effect ◽  
Fluorescent Probe ◽  
Intracellular Ph ◽  
Intramolecular Charge Transfer ◽  
Uv Light

A light-activated fluorescent probe shows cycle-reversible intramolecular charge transfer for different intracellular pH under the synergistic effect of protonation–deprotonation.

A Novel Dual-functional Fluorescent Probe for Imaging Viscosity and Cysteine in Living System

2021 ◽  
Author(s):  
Manlin Fu ◽  
Kai Wang ◽  
Qiancheng Ma ◽  
Mianli Bian ◽  
Qing Zhu
Keyword(s):  
Fluorescent Probe ◽  
Redox Reaction ◽  
Living System ◽  
Pivotal Role ◽  
Biological Processes ◽  
Dual Functional ◽  
Reversible Redox

Abnormal changes in intracellular viscosity and cysteine are both associated with several important biological processes such as reversible redox reaction, which plays a pivotal role in the process of inflammation....

scholarly journals A Near-Infrared Fluorescent Probe Based on a FRET Rhodamine Donor Linked to a Cyanine Acceptor for Sensitive Detection of Intracellular pH Alternations

Molecules ◽  
2018 ◽  
Vol 23 (10) ◽  
pp. 2679 ◽  
Author(s):  
Yibin Zhang ◽  
Jianheng Bi ◽  
Shuai Xia ◽  
Wafa Mazi ◽  
Shulin Wan ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Intracellular Ph ◽  
Near Infrared ◽  
Resonance Energy Transfer ◽  
Resonance Energy ◽  
Sensitive Detection ◽  
Solution Ph ◽  
Acidic Conditions ◽  
Ph Level ◽  
Rhodamine Dye

A fluorescence resonance energy transfer (FRET)-based near-infrared fluorescent probe (B+) for double-checked sensitive detection of intracellular pH changes has been synthesized by binding a near-infrared rhodamine donor to a near-infrared cyanine acceptor through robust C-N bonds via a nucleophilic substitution reaction. To demonstrate the double-checked advantages of probe B+, a near-infrared probe (A) was also prepared by modification of a near-infrared rhodamine dye with ethylenediamine to produce a closed spirolactam residue. Under basic conditions, probe B+ shows only weak fluorescence from the cyanine acceptor while probe A displays nonfluorescence due to retention of the closed spirolactam form of the rhodamine moiety. Upon decrease in solution pH level, probe B+ exhibits a gradual fluorescence increase from rhodamine and cyanine constituents at 623 nm and 743 nm respectively, whereas probe A displays fluorescence increase at 623 nm on the rhodamine moiety as acidic conditions leads to the rupture of the probe spirolactam rings. Probes A and B+ have successfully been used to monitor intracellular pH alternations and possess pKa values of 5.15 and 7.80, respectively.

A Dual Functional Electroactive and Fluorescent Probe for Coupled Measurements of Vesicular Exocytosis with High Spatial and Temporal Resolution

2017 ◽  
Vol 129 (9) ◽  
pp. 2406-2410 ◽  
Author(s):  
Xiaoqing Liu ◽  
Alexandra Savy ◽  
Sylvie Maurin ◽  
Laurence Grimaud ◽  
François Darchen ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Temporal Resolution ◽  
Dual Functional ◽  
Vesicular Exocytosis

Nopinone-based AIE-active dual-functional fluorescent chemosensor for Hg2+ and Cu2+ and its environmental and biological applications

2020 ◽  
Vol 49 (43) ◽  
pp. 15299-15309
Author(s):  
Mingxin Li ◽  
Shutang Ruan ◽  
Haiyan Yang ◽  
Yan Zhang ◽  
Yiqin Yang ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Environmental Analysis ◽  
Fluorescent Chemosensor ◽  
Biological Applications ◽  
Dual Functional

A nopinone-based dual-functional fluorescent probe for Hg2+ and Cu2+ and its applications in environmental analysis and bioimaging.

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