Chitosan/poly(γ-glutamic acid) nanoparticles incorporating IFN-γ for immune response modulation in the context of colorectal cancer

2019 ◽  
Vol 7 (8) ◽  
pp. 3386-3403 ◽  
Author(s):  
Flávia Castro ◽  
Marta L. Pinto ◽  
Rui Almeida ◽  
Flávia Pereira ◽  
Andreia M. Silva ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Immune Response ◽  
Synergistic Effect ◽  
Glutamic Acid ◽  
Anticancer Therapy ◽  
Response Modulation ◽  
Ifn Γ ◽  
Immune Response Modulation

This work highlights the potential synergistic effect of chitosan/γ-PGA nanoparticles with immunomodulatory cytokines, like IFN-γ, for anticancer therapy.

Semiautomated microfluorometric instrument and reagent system for monitoring disease-related immunosuppression.

1982 ◽  
Vol 28 (9) ◽  
pp. 1887-1893 ◽  
Author(s):  
D F Ranney ◽  
A J Quattrone
Keyword(s):  
Immune Response ◽  
Dna Content ◽  
Peripheral Blood ◽  
Fluorescence Enhancement ◽  
Photon Counting ◽  
Peripheral Blood Lymphocytes ◽  
Response Modulation ◽  
Blood Lymphocytes ◽  
Complex Test ◽  
Immune Response Modulation

Abstract Several common metabolites and drugs in the serum in of patients with inflammatory, infectious, autoimmune, immunodeficient, neoplastic, and toxicant-induced diseases can produce artifactual suppression of the [methyl-3H]-thymidine assay, which is widely used to evaluate lymphocyte responsiveness. We have developed a sensitive, semiautomated, fluorescence-enhancement assay in which true immunosuppressors are measured in the presence of absence of such interfering substances. Peripheral blood lymphocytes are activated with mitogens in standard microtiter culture trays. Changes in lymphocyte DNA content are quantified with a reagent formulation containing mithramycin, the fluorescence of which is enhanced on binding to DNA in the presence of MgCl2. We solubilize cells within the intact microtiter tray by using an automated, inverted "Array Sonicator," and measure fluorescence with an automated, photon-counting fluorometer. With this system, immune response modulation can be accurately assessed in the presence of patients' sera and other complex test substances (e.g., supernates from hybridomas, fermentation vats, viral preparations, and macrophage cultures.

IMMUNE RESPONSE MODULATION BY PENTOXIFYLLINE IN VITRO

1993 ◽  
Vol 56 (1) ◽  
pp. 196-201 ◽  
Author(s):  
HERBERT TILG ◽  
BRIGITTE EIBL ◽  
MARION PICHL ◽  
ANNE GÄCHTER ◽  
MANFRED HEROLD ◽  
...  
Keyword(s):  
Immune Response ◽  
Response Modulation ◽  
Immune Response Modulation

scholarly journals The role of balanced supplementation in diet of age-related macular degeneration patients

2021 ◽  
Vol 8 (1) ◽  
pp. 19-25
Author(s):  
Iwona Kusz vel Sobczuk ◽  
Anna Święch
Keyword(s):  
Vitamin D ◽  
Immune Response ◽  
Macular Degeneration ◽  
Vitamin B6 ◽  
Age Related Macular Degeneration ◽  
Response Modulation ◽  
Omega 3 ◽  
Age Related ◽  
Immune Response Modulation

Aim: The aim of the article was to discuss the role of balanced supplementation in diet of age-related macular degeneration patients. Methods: This review was carried out using comprehensive and systematic literature reports on the role of supplementation of vitamin D, vitamin C, vitamin E, vitamin B6, vitamin B12, zinc, lutein, zeaxanthin, omega-3 acid and folic acid in the prevention of AMD. Results: Vitamins, minerals and carotenoids are essential for the proper retinal function over an inflammation and immune response modulation. Conclusions: Vitamins, minerals and carotenoids discussed in the article have anti-inflammatory and antioxidative properties in the management of AMD progression. Accordingly, it is relevant to assure the appropriate level of these nutrients in a diet of AMD patients.

scholarly journals Author Correction: Differential immune response modulation in early Leishmania amazonensis infection of BALB/c and C57BL/6 macrophages based on transcriptome profiles

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Juliana Ide Aoki ◽  
Sandra Marcia Muxel ◽  
Ricardo Andrade Zampieri ◽  
Karl Erik Müller ◽  
Audun Helge Nerland ◽  
...  
Keyword(s):  
Immune Response ◽  
Leishmania Amazonensis ◽  
Response Modulation ◽  
Immune Response Modulation

scholarly journals Immune Response Modulation by Caliciviruses

2019 ◽  
Vol 10 ◽  
Author(s):  
Yoatzin Peñaflor-Téllez ◽  
Adrian Trujillo-Uscanga ◽  
Jesús Alejandro Escobar-Almazán ◽  
Ana Lorena Gutiérrez-Escolano
Keyword(s):  
Immune Response ◽  
Response Modulation ◽  
Immune Response Modulation

Immune Response Modulation After Burn Injury

1987 ◽  
Vol 8 (6) ◽  
pp. 509-512 ◽  
Author(s):  
John F. Hansbrough ◽  
Thomas O. Field ◽  
Michele A. Gadd ◽  
C. Soderberg
Keyword(s):  
Immune Response ◽  
Burn Injury ◽  
Response Modulation ◽  
Immune Response Modulation
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