Performance of a template enhanced hybridization process in biological media for the detection of a breast cancer biomarker

2020 ◽  
Vol 12 (6) ◽  
pp. 839-847
Author(s):  
Reyhaneh Tavakoli-Koopaei ◽  
Fatemeh Javadi-Zarnaghi ◽  
Maedeh Aghahosseini ◽  
Manoochehr Tavassoli ◽  
Mohammad Javad Rasaee
Keyword(s):  
Breast Cancer ◽  
Cancer Biomarker ◽  
Biological Media ◽  
G Quadruplex ◽  
Colorimetric Assays

A split G-quadruplex DNAzyme have been used for analysis of microRNA mimics in biological media with colorimetric assays based on Template enhanced Hybridization Processes, TeHyP.

scholarly journals Fabrication of an immunosensor for quantitative detection of breast cancer biomarker UBE2C

RSC Advances ◽  
2019 ◽  
Vol 9 (29) ◽  
pp. 16738-16745 ◽  
Author(s):  
V. S. P. K. Sankara Aditya Jayanthi ◽  
Asim Bikas Das ◽  
Urmila Saxena
Keyword(s):  
Breast Cancer ◽  
Modified Electrode ◽  
Cancer Biomarker ◽  
Quantitative Detection

Antibodies crosslinking on PANI modified electrode to design a highly selective immunosensor to detect UBE2C.

scholarly journals Optical multiplexed bioassays on photonic crystals for breast cancer biomarker detection

2021 ◽  
Vol 255 ◽  
pp. 13003
Author(s):  
Tommaso Pileri ◽  
Alberto Sinibaldi ◽  
Agostino Occhicone ◽  
Elena Giordani ◽  
Matteo Allegretti ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Specific Interaction ◽  
Fluorescence Emission ◽  
Optical Biosensor ◽  
Cancer Biomarker ◽  
Time Development ◽  
Biomarker Detection ◽  
Label Free ◽  
One Dimensional ◽  
Protein Bovine Serum Albumin

An optical biosensor for proteomic breast cancer biomarker detection in complex media is presented. Bloch Surface Waves (BSW) excited onto one dimensional photonic crystal (1DPC) were used to probe the interaction of HER2 with three antibody species and an inert protein (Bovine Serum Albumin - BSA). The optical system combines Label-Free readings to track the bioassay real-time development and Fluorescence emission quantification to evaluate the level of specific interaction between the antigen and the antibodies. The results confirm a distinguishable level of affinity between the antibodies and the analyte according to their specificity even at low antibody surface density (about 1173 pg/mm2).

scholarly journals HER2 breast cancer biomarker detection using a sandwich optical fiber assay

Talanta ◽  
2021 ◽  
Vol 221 ◽  
pp. 121452 ◽  
Author(s):  
Médéric Loyez ◽  
Maxime Lobry ◽  
Eman M. Hassan ◽  
Maria C. DeRosa ◽  
Christophe Caucheteur ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Optical Fiber ◽  
Cancer Biomarker ◽  
Biomarker Detection ◽  
Her2 Breast Cancer
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