A label-free small molecular hydrogel-based electrochemical immunosensor for ultrasensitive detection of deoxynivalenol

2019 ◽  
Vol 11 (47) ◽  
pp. 5948-5952 ◽  
Author(s):  
Yu Peng ◽  
Lifang Geng ◽  
Xinyi Liu ◽  
Min Liu ◽  
Haoru Wu ◽  
...  
Keyword(s):  
Electrochemical Immunosensor ◽  
Ultrasensitive Detection ◽  
Label Free ◽  
Electrochemical Immunosensing

A guanosine-based small-molecular hydrogel is developed as a label-free electrochemical immunosensing platform for ultrasensitive detection of deoxynivalenol.

Construction of electrochemical immunosensor based on redox hydrogel for ultrasensitive detection of carcinoembryonic antigen

2021 ◽  
Author(s):  
Xiangrong Huang ◽  
Na Wu ◽  
Wenxiu Liu ◽  
Yazhuo Shang ◽  
Honglai Liu ◽  
...  
Keyword(s):  
Methylene Blue ◽  
Carcinoembryonic Antigen ◽  
Electrochemical Detection ◽  
Electrochemical Immunosensor ◽  
Ultrasensitive Detection ◽  
Label Free

In this work, a novel redox hydrogel was proposed for ultrasensitive label-free electrochemical detection of carcinoembryonic antigen (CEA). The redox hydrogel composed by cellulose nanocrystalline (CNC), methylene blue (MB), multi-walled...

Label-free electrochemical immunosensor based on gold nanoparticle/polyethyleneimine/reduced graphene oxide nanocomposite for the ultrasensitive detection of cancer biomarker matrix metalloproteinase-1

The Analyst ◽  
2021 ◽  
Author(s):  
Xinke Liu ◽  
Lu-Yin Lin ◽  
Fu-Yen Tseng ◽  
Yu-Cheng Tan ◽  
Jian Li ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Matrix Metalloproteinase ◽  
Gold Nanoparticle ◽  
Reduced Graphene Oxide ◽  
Electrochemical Immunosensor ◽  
Ultrasensitive Detection ◽  
Label Free ◽  
Matrix Metalloproteinase 1 ◽  
Reduced Graphene ◽  
P Matrix

Matrix metalloproteinase-1 (MMP-1) is associated with many types of cancers, including oral, colorectal, and brain cancers. This paper describes the fabrication of an MMP-1 immunosensor based on a gold nanoparticle/polyethyleneimine/reduced...

Ultrasensitive detection of kanamycin in animal derived foods by label-free electrochemical immunosensor

2012 ◽  
Vol 134 (3) ◽  
pp. 1601-1606 ◽  
Author(s):  
Qin Wei ◽  
Yanfang Zhao ◽  
Bin Du ◽  
Dan Wu ◽  
He Li ◽  
...  
Keyword(s):  
Electrochemical Immunosensor ◽  
Ultrasensitive Detection ◽  
Label Free

Dual-mode label-free electrochemical immunosensor for ultrasensitive detection of procalcitonin based on g-C3N4-NiCo2S4-CNTs-Ag NPs

The Analyst ◽  
2021 ◽  
Author(s):  
Xiaoting Xu ◽  
Xuan Li ◽  
Juncong Miao ◽  
Lei Liu ◽  
Xinyi Huang ◽  
...  
Keyword(s):  
Differential Pulse Voltammetry ◽  
Differential Pulse ◽  
Electrochemical Immunosensor ◽  
Mode Analysis ◽  
Quantitative Detection ◽  
Ultrasensitive Detection ◽  
Label Free ◽  
Dual Mode ◽  
Ag Nps ◽  
Pulse Voltammetry

Herein, a label-free electrochemical immunosensor which based on Differential Pulse Voltammetry (DPV) and Amperometric i-t curve (i-t) dual-mode analysis is proposed for early quantitative detection of procalcitonin (PCT). Thanks to...

scholarly journals A label-free immunosensor based on PHEMA/graphene oxide nanocomposite for simultaneous electrochemical determination of alpha fetoprotein

RSC Advances ◽  
2019 ◽  
Vol 9 (30) ◽  
pp. 17187-17193 ◽  
Author(s):  
Ying Liang ◽  
Xiaoqing Zhao ◽  
Na Wang ◽  
Jing Wang ◽  
Hou Chen ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Electrochemical Determination ◽  
Electrochemical Immunosensor ◽  
Alpha Fetoprotein ◽  
Ultrasensitive Detection ◽  
Hydroxyethyl Methacrylate ◽  
Label Free

An electrochemical immunosensor based on poly(2-hydroxyethyl methacrylate) (PHEMA)/graphene oxide (GO) nanocomposite was designed in a simple way for the ultrasensitive detection of tumor makers (alpha-fetoprotein, AFP as a model).

scholarly journals A Bifunctional Nanosilver-Reduced Graphene Oxide Nanocomposite for Label-Free Electrochemical Immunosensing

2021 ◽  
Vol 9 ◽  
Author(s):  
Supakeit Chanarsa ◽  
Jaroon Jakmunee ◽  
Kontad Ounnunkad
Keyword(s):  
Graphene Oxide ◽  
Reduced Graphene Oxide ◽  
Limit Of Detection ◽  
Electrochemical Immunosensor ◽  
Label Free ◽  
One Pot ◽  
Reduced Graphene ◽  
Sensitivity And Selectivity ◽  
Analytical Response ◽  
Electrochemical Immunosensing

A bi-functional material based on silver nanoparticles (AgNPs)-reduced graphene oxide (rGO) composite for both electrode modification and signal generation is successfully synthesized for use in the construction of a label-free electrochemical immunosensor. An AgNPs/rGO nanocomposite is prepared by a one-pot wet chemical process. The AgNPs/rGO composite dispersion is simply cast on a screen-printed carbon electrode (SPCE) to fabricate the electrochemical immunosensor. It possesses a sufficient conductivity/electroreactivity and improves the electrode reactivity of SPCE. Moreover, the material can generate an analytical response due to the formation of immunocomplexes for detection of human immunoglobulin G (IgG), a model biomarker. Based on electrochemical stripping of AgNPs, the material reveals signal amplification without external redox molecules/probes. Under optimized conditions, the square wave voltammetric peak current is responded to the logarithm of IgG concentration in two wide linear ranges from 1 to 50 pg.ml−1 and 0.05 to 50 ng.ml−1, and the limit of detection (LOD) is estimated to be 0.86 pg.ml−1. The proposed immunosensor displays satisfactory sensitivity and selectivity. Importantly, detection of IgG in human serum using the immunosensor shows satisfactory accuracy, suggesting that the immunosensor possesses a huge potential for further development in clinical diagnosis.

Sign in / Sign up

Export Citation Format

Share Document