An automated high-throughput sample preparation method using double-filtration for serum metabolite LC-MS analysis

2019 ◽  
Vol 11 (31) ◽  
pp. 4060-4065 ◽  
Author(s):  
Minjoong Joo ◽  
Jong-Moon Park ◽  
Van-An Duong ◽  
Dami Kwon ◽  
Jongho Jeon ◽  
...  
Keyword(s):  
Sample Preparation ◽  
High Throughput ◽  
Preparation Method ◽  
Sample Preparation Method ◽  
Ms Analysis ◽  
System P ◽  
Filtration System ◽  
Automated Sample Preparation ◽  
Double Filtration

A novel, automated sample preparation method for serum metabolite LC-MS analysis was developed using a double-filtration system.

scholarly journals Sample preparation method to improve the efficiency of high-throughput single-molecule force spectroscopy

2019 ◽  
Vol 5 (4) ◽  
pp. 176-183 ◽  
Author(s):  
Lei Jin ◽  
Li Kou ◽  
Yanan Zeng ◽  
Chunguang Hu ◽  
Xiaodong Hu
Keyword(s):  
Sample Preparation ◽  
High Throughput ◽  
Single Molecule ◽  
Preparation Method ◽  
Force Spectroscopy ◽  
Experimental Result ◽  
Sample Preparation Method ◽  
Dna Stretching ◽  
Single Molecule Force Spectroscopy ◽  
Preparation Methods

Abstract Inefficient sample preparation methods hinder the performance of high-throughput single-molecule force spectroscopy (H-SMFS) for viscous damping among reactants and unstable linkage. Here, we demonstrated a sample preparation method for H-SMFS systems to achieve a higher ratio of effective target molecules per sample cell by gas-phase silanization and reactant hydrophobization. Digital holographic centrifugal force microscopy (DH-CFM) was used to verify its performance. The experimental result indicated that the DNA stretching success ratio was improved from 0.89% to 13.5%. This enhanced efficiency preparation method has potential application for force-based DNA stretching experiments and other modifying procedures.

Development of an automated sample preparation method for HCV

1997 ◽  
Vol 30 (3) ◽  
pp. 240
Author(s):  
J.R. Hildebrandt ◽  
T. Picone ◽  
E. Reitz ◽  
Z. Li ◽  
M. Fairchild ◽  
...  
Keyword(s):  
Sample Preparation ◽  
Preparation Method ◽  
Sample Preparation Method ◽  
Automated Sample Preparation

Simple and Robust Two-Layer Matrix/Sample Preparation Method for MALDI MS/MS Analysis of Peptides

2005 ◽  
Vol 4 (5) ◽  
pp. 1709-1716 ◽  
Author(s):  
Jing Zheng ◽  
Nan Li ◽  
Marc Ridyard ◽  
Hui Dai ◽  
Stephen M. Robbins ◽  
...  
Keyword(s):  
Sample Preparation ◽  
Preparation Method ◽  
Maldi Ms ◽  
Sample Preparation Method ◽  
Ms Analysis ◽  
Matrix Sample
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