A comparative study of microporous polyolefin silica-based paper and cellulose paper substrates utilizing paper spray-mass spectrometry in drug analysis

2019 ◽  
Vol 11 (24) ◽  
pp. 3066-3072 ◽  
Author(s):  
Imesha W. De Silva ◽  
Darren T. Converse ◽  
Lauren A. Juel ◽  
Guido F. Verbeck
Keyword(s):  
Mass Spectrometry ◽  
Comparative Study ◽  
Drug Analysis ◽  
Efficient Technique ◽  
Fast Analysis ◽  
Paper Spray ◽  
Cellulose Paper ◽  
Synthetic Substrate ◽  
Paper Substrates

This comparative study proposes an efficient technique by employing a synthetic substrate, which is commercially available, for direct, sensitive, efficient and fast analysis in Paper Spray Mass Spectrometry (PS-MS).

2D wax-printed paper substrates with extended solvent supply capabilities allow enhanced ion signal in paper spray ionization

The Analyst ◽  
2016 ◽  
Vol 141 (12) ◽  
pp. 3866-3873 ◽  
Author(s):  
Deidre E. Damon ◽  
Yosef S. Maher ◽  
Mengzhen Yin ◽  
Fred P. M. Jjunju ◽  
Iain S. Young ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Organic Compounds ◽  
Microfluidic Channels ◽  
Paper Spray ◽  
Paper Spray Ionization ◽  
Ms Analysis ◽  
Wax Printing ◽  
Paper Substrates

Paper-based microfluidic channels were created from solid wax printing, and the resultant 2D wax-printed paper substrates were used for paper spray (PS) mass spectrometry (MS) analysis of small organic compounds.

Fast analysis of caffeine in beverages and drugs by paper spray tandem mass spectrometry

2016 ◽  
Vol 408 (14) ◽  
pp. 3783-3787 ◽  
Author(s):  
Domenico Taverna ◽  
Leonardo Di Donna ◽  
Lucia Bartella ◽  
Anna Napoli ◽  
Giovanni Sindona ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Tandem Mass Spectrometry ◽  
Tandem Mass ◽  
Fast Analysis ◽  
Paper Spray

Facile preparation of paper substrates coated with different materials and their applications in paper spray mass spectrometry

2015 ◽  
Vol 7 (13) ◽  
pp. 5381-5386 ◽  
Author(s):  
Yajun Zheng ◽  
Xiaoling Zhang ◽  
Haijun Yang ◽  
Xiaoning Liu ◽  
Xinrong Zhang ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Filter Paper ◽  
Paper Spray ◽  
Vacuum Filtration ◽  
Facile Preparation ◽  
Paper Substrates

A versatile strategy based on vacuum filtration is introduced for coating different well-defined materials on the surface of filter paper.

Metal–organic framework coated paper substrates for paper spray mass spectrometry

2016 ◽  
Vol 8 (45) ◽  
pp. 8004-8014 ◽  
Author(s):  
Xiaoting Wang ◽  
Yajun Zheng ◽  
Teng Wang ◽  
Xingchuang Xiong ◽  
Xiang Fang ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Metal Organic Framework ◽  
Coated Paper ◽  
Paper Spray ◽  
Metal Organic ◽  
Paper Substrates ◽  
Organic Framework

Rapid Diagnosis of Parkinson’s Disease from Sebum using Paper Spray Ionisation Ion Mobility Mass Spectrometry

2020 ◽  
Author(s):  
Depanjan Sarkar ◽  
Drupad Trivedi ◽  
Eleanor Sinclair ◽  
Sze Hway Lim ◽  
Caitlin Walton-Doyle ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Ion Mobility ◽  
Neurodegenerative Disorder ◽  
Treatment Options ◽  
Ion Mobility Mass Spectrometry ◽  
Paper Spray ◽  
Molecular Features ◽  
Validation Set

Parkinson’s disease (PD) is the second most common neurodegenerative disorder for which identification of robust biomarkers to complement clinical PD diagnosis would accelerate treatment options and help to stratify disease progression. Here we demonstrate the use of paper spray ionisation coupled with ion mobility mass spectrometry (PSI IM-MS) to determine diagnostic molecular features of PD in sebum. PSI IM-MS was performed directly from skin swabs, collected from 34 people with PD and 30 matched control subjects as a training set and a further 91 samples from 5 different collection sites as a validation set. PSI IM-MS elucidates ~ 4200 features from each individual and we report two classes of lipids (namely phosphatidylcholine and cardiolipin) that differ significantly in the sebum of people with PD. Putative metabolite annotations are obtained using tandem mass spectrometry experiments combined with accurate mass measurements. Sample preparation and PSI IM-MS analysis and diagnosis can be performed ~5 minutes per sample offering a new route to for rapid and inexpensive confirmatory diagnosis of this disease.

scholarly journals Rapid Distinction and Semiquantitative Analysis of THC and CBD by Silver-Impregnated Paper Spray Mass Spectrometry

2021 ◽  
Author(s):  
Si Huang ◽  
Frank W. Claassen ◽  
Teris A. van Beek ◽  
Bo Chen ◽  
Jianguo Zeng ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Semiquantitative Analysis ◽  
Paper Spray

High-throughput determination of flavanone-O-glycosides in citrus beverages by paper spray tandem mass spectrometry

2021 ◽  
pp. 130060
Author(s):  
Fabio Mazzotti ◽  
Lucia Bartella ◽  
Ines Rosita Talarico ◽  
Anna Napoli ◽  
Leonardo Di Donna
Keyword(s):  
Mass Spectrometry ◽  
Tandem Mass Spectrometry ◽  
High Throughput ◽  
Tandem Mass ◽  
Paper Spray
Sign in / Sign up

Export Citation Format

Share Document