An electrochemical immunosensor for prostate specific antigen using nitrogen-doped graphene as a sensing platform

2019 ◽  
Vol 11 (16) ◽  
pp. 2183-2189 ◽  
Author(s):  
Wenwen Meng ◽  
Wenjuan Zhang ◽  
JunJun Zhang ◽  
Xi Chen ◽  
Yuzhong Zhang

In this study, a sensitive electrochemical immunosensor for prostate specific antigen (PSA) detection is described using nitrogen-doped graphene (NG) and gold nanoparticles (Au NPs) as a sensing interface.

2021 ◽  
Author(s):  
Mengrao Li ◽  
Wenjuan Zhang ◽  
Yuzhong Zhang

In this work, we reported a simple and sensitive electrochemical immunosensor for cancer biomarkers PSA detection. In design protocol, gold nanoparticles (Au NPs) were used a carrier to load aptamer...


Nanomaterials ◽  
2019 ◽  
Vol 9 (9) ◽  
pp. 1236 ◽  
Author(s):  
Giulia Neri ◽  
Enza Fazio ◽  
Placido Giuseppe Mineo ◽  
Angela Scala ◽  
Anna Piperno

The development of graphene (G) substrates without damage on the sp2 network allows to tune the interactions with plasmonic noble metal surfaces to finally enhance surface enhanced Raman spectroscopy (SERS) effect. Here, we describe a new graphene/gold nanocomposite obtained by loading gold nanoparticles (Au NPs), produced by pulsed laser ablation in liquids (PLAL), on a new nitrogen-doped graphene platform (G-NH2). The graphene platform was synthesized by direct delamination and chemical functionalization of graphite flakes with 4-methyl-2-p-nitrophenyl oxazolone, followed by reduction of p-nitrophenyl groups. Finally, the G-NH2/Au SERS platform was prepared by using the conventional aerography spraying technique. SERS properties of G-NH2/Au were tested using Rhodamine 6G (Rh6G) and Dopamine (DA) as molecular probes. Raman features of Rh6G and DA are still detectable for concentration values down to 1 × 10−5 M and 1 × 10−6 M respectively.


2016 ◽  
Vol 227 ◽  
pp. 524-532 ◽  
Author(s):  
Chayada Saengsookwaow ◽  
Ratthapol Rangkupan ◽  
Orawon Chailapakul ◽  
Nadnudda Rodthongkum

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