Quantitative detection of procalcitonin using an electrochemical immunosensor based on MoO3/Au@rGO nanocomposites

The Analyst ◽  
2019 ◽  
Vol 144 (23) ◽  
pp. 6968-6974 ◽  
Author(s):  
Jianqiao Liu ◽  
Li Quan ◽  
Xuelian Yu ◽  
Lin Wang
Keyword(s):  
Electrochemical Immunosensor ◽  
Quantitative Detection ◽  
Layer By Layer ◽  
Sandwich Type

In this work, a sandwich-type electrochemical immunosensor for the detection of procalcitonin (PCT) is constructed layer-by-layer with a novel label based on MoO3/Au@rGO nanocomposites.

Layer-by-layer self-assembly of 2D graphene nanosheets, 3D copper oxide nanoflowers and 0D gold nanoparticles for ultrasensitive electrochemical detection of alpha fetoprotein

RSC Advances ◽  
2015 ◽  
Vol 5 (70) ◽  
pp. 56583-56589 ◽  
Author(s):  
Yulan Wang ◽  
Dan Wu ◽  
Yong Zhang ◽  
Xiang Ren ◽  
Yaoguang Wang ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Copper Oxide ◽  
Electrochemical Detection ◽  
Self Assembly ◽  
Graphene Nanosheets ◽  
Electrochemical Immunosensor ◽  
Alpha Fetoprotein ◽  
Quantitative Detection ◽  
Layer By Layer ◽  
Label Free

In this work, a novel and ultrasensitive label-free electrochemical immunosensor was developed for the quantitative detection of alpha fetoprotein (AFP).

scholarly journals A sensitive non-enzymatic immunosensor composed of silver nanoflowers for squamous cell carcinoma antigen

RSC Advances ◽  
2017 ◽  
Vol 7 (4) ◽  
pp. 2242-2248 ◽  
Author(s):  
Yueyun Li ◽  
Yihe Zhang ◽  
Jian Han ◽  
Paul K. Chu ◽  
Jinhui Feng ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Electrochemical Immunosensor ◽  
Quantitative Detection ◽  
Squamous Cell Carcinoma Antigen ◽  
Sandwich Type

In this work, a sensitive sandwich-type non-enzymatic electrochemical immunosensor for quantitative detection of squamous cell carcinoma antigen (SCCA) is designed and fabricated.

A sandwich-type electrochemical immunosensor using polythionine/AuNPs nanocomposites as label for ultrasensitive detection of carcinoembryonic antigen

2019 ◽  
Vol 9 (5) ◽  
pp. 444-450 ◽  
Author(s):  
Yuxuan Lai ◽  
Hao Huang ◽  
Zhihuan Xia ◽  
Song Li ◽  
Yan Deng ◽  
...  
Keyword(s):  
Carcinoembryonic Antigen ◽  
Surface Area ◽  
Chemical Reduction ◽  
Electrochemical Immunosensor ◽  
Cancer Diagnostics ◽  
Active Surface Area ◽  
Layer By Layer ◽  
Glass Carbon Electrode ◽  
Wide Range ◽  
Sandwich Type

A sandwich-type electrochemical immunosensor was developed in this study for sensitive detection of carcinoembryonic antigen (CEA) based on rGO/CS/AuNPs as a sensing platform and PTh-Au composites as signal labels. Reduced graphene oxide (rGO), Chitosan (CS) and AuNPs were layer by layer modified on glass carbon electrode (GCE), which effectively enhanced electron transfer and provided excellent large electrochemical active surface area. Polythionine-Au composites prepared by chemical reduction method greatly amplified electrochemical signal with high conductivity and large surface area. The prepared immunosensor showed high sensitivity, good stability and selectivity for detection of CEA with a wide range of 0.3 ng/mL to 30 ng/mL (R2 = 0.9972) and a detection limit as low as 0.1471 pg/mL. Furthermore, this sandwich-type immunosensor might be as a versatile platform for reliable early cancer diagnostics clinical.

Application of three-dimensional flower-like nanomaterials in the fabrication of sandwich-type electrochemical immunosensors

RSC Advances ◽  
2015 ◽  
Vol 5 (107) ◽  
pp. 88160-88165 ◽  
Author(s):  
Yulan Wang ◽  
Yan Li ◽  
Lihua Hu ◽  
Xiang Ren ◽  
Bin Du ◽  
...  
Keyword(s):  
Carcinoembryonic Antigen ◽  
Three Dimensional ◽  
Electrochemical Immunosensor ◽  
Quantitative Detection ◽  
Electrochemical Immunosensors ◽  
Sandwich Type

A novel and ultrasensitive sandwich-type electrochemical immunosensor was developed for the quantitative detection of carcinoembryonic antigen (CEA) in this work.

Electrochemical Immunosensors Based on Nanostructured Materials for Sensing of Prostate-Specific Antigen: A Review

2020 ◽  
Vol 28 ◽  
Author(s):  
Hayati Filik ◽  
Asiye Aslıhan Avan ◽  
Mustafa Özyürek
Keyword(s):  
Prostate Specific Antigen ◽  
Nanostructured Materials ◽  
Specific Antigen ◽  
Electrochemical Immunosensor ◽  
Label Free ◽  
Electrochemical Immunosensors ◽  
Metal Metal ◽  
Different Types ◽  
Sandwich Type ◽  
Carbon Based Nanomaterials

: The prostate-specific antigen (PSA) has been considered a crucial serological marker for distinguishing prostate based cancer. This surveys recent progress in the construction of nanomaterial-based electrochemical immunosensors for a PSA. This review (from 2015 to 2020) reports the latest progress in PSA sensing based on the employ of different types of nanostructured materials. The most popular used nanostructured materials are metal, metal oxide, carbon-based nanomaterials, and their hybrid architectures utilized for distinct amplification protocols. In this review, the electrochemical immunosensors for prostate-specific antigen sensing are classified into three categories such as sandwich type@labeled, label free@nonlabeled and aptamer-based electrochemical immunosensor.

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