Enhanced highly toxic reactive oxygen species levels from iron oxide core–shell mesoporous silica nanocarrier-mediated Fenton reactions for cancer therapy

2018 ◽  
Vol 6 (37) ◽  
pp. 5876-5887 ◽  
Author(s):  
Kai Sun ◽  
Zhiguo Gao ◽  
Yu Zhang ◽  
Hongshuai Wu ◽  
Chaoqun You ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Iron Oxide ◽  
Cancer Therapy ◽  
Mesoporous Silica ◽  
Reactive Oxygen ◽  
Core Shell ◽  
Oxygen Species ◽  
Iron Oxide Core

Highly toxic reactive oxygen species levels were enhanced via iron oxide core–shell mesoporous silica nanocarrier-mediated Fenton reactions for cancer therapy.

scholarly journals Ultrasound-induced reactive oxygen species generation and mitochondria-specific damage by sonodynamic agent/metal ion-doped mesoporous silica

RSC Advances ◽  
2019 ◽  
Vol 9 (68) ◽  
pp. 39924-39931 ◽  
Author(s):  
Kecan Lin ◽  
Ziguo Lin ◽  
Yujie Li ◽  
Youshi Zheng ◽  
Da Zhang
Keyword(s):  
Reactive Oxygen Species ◽  
Tumor Microenvironment ◽  
Cancer Therapy ◽  
Mesoporous Silica ◽  
Metal Ion ◽  
Reactive Oxygen Species Generation ◽  
Reactive Oxygen ◽  
Oxygen Species

Herein, we design tumor microenvironment specific active nano sono-chemodynamic agent for synergistic photodynamic–chemodynamic cancer therapy.

scholarly journals Conducting polymer nanoparticles for targeted cancer therapy

RSC Advances ◽  
2015 ◽  
Vol 5 (47) ◽  
pp. 37943-37956 ◽  
Author(s):  
Mona Doshi ◽  
Marissa Krienke ◽  
Saeid Khederzadeh ◽  
Henry Sanchez ◽  
Alicja Copik ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Cancer Therapy ◽  
Conducting Polymer ◽  
Targeted Delivery ◽  
Reactive Oxygen ◽  
Polymer Nanoparticles ◽  
Oxygen Species ◽  
Targeted Cancer Therapy ◽  
Fluorescence Bioimaging

Functionalized conducting polymer nanoparticles allow for targeted delivery, tracking by fluorescence bioimaging, and therapeutics through formation of reactive oxygen species.

A glucose-depleting silica nanosystem for increasing reactive oxygen species and scavenging glutathione in cancer therapy

2019 ◽  
Vol 55 (89) ◽  
pp. 13374-13377 ◽  
Author(s):  
Wee Kong Ong ◽  
Deblin Jana ◽  
Yanli Zhao
Keyword(s):  
Reactive Oxygen Species ◽  
Hydrogen Peroxide ◽  
Cancer Therapy ◽  
Reactive Oxygen ◽  
Species Level ◽  
Reactive Oxygen Species Level ◽  
Oxygen Species ◽  
Anticancer Treatment ◽  
Intracellular Glucose

A novel silica nanosystem is fabricated to convert intracellular glucose to hydrogen peroxide for enhancing reactive oxygen species level and triggering p-quinomethane release to scavenge glutathione, achieving synergistic anticancer treatment.

scholarly journals Integration of intracellular telomerase monitoring by electrochemiluminescence technology and targeted cancer therapy by reactive oxygen species

2017 ◽  
Vol 8 (12) ◽  
pp. 8025-8029 ◽  
Author(s):  
Huairong Zhang ◽  
Binxiao Li ◽  
Zhaomei Sun ◽  
Hong Zhou ◽  
Shusheng Zhang
Keyword(s):  
Reactive Oxygen Species ◽  
Cancer Therapy ◽  
Cancer Cells ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Targeted Cancer Therapy ◽  
High Efficacy

ROS and polyluminol–Pt NPs were used for intracellular telomerase detection and to induce apoptosis in HL-60 cancer cells with high efficacy.

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