scholarly journals Highly selective, red emitting BODIPY-based fluorescent indicators for intracellular Mg2+ imaging

2018 ◽  
Vol 6 (44) ◽  
pp. 7247-7256 ◽  
Author(s):  
Qitian Lin ◽  
Daniela Buccella

New fluorescent sensors with excellent turn-on ratio and low energy excitation provide Mg2+ detection in live cells with high selectivity.

2016 ◽  
Vol 14 (48) ◽  
pp. 11381-11388 ◽  
Author(s):  
Qitian Lin ◽  
Jessica J. Gruskos ◽  
Daniela Buccella

A new fluorescent sensor with excellent turn-on ratio, low energy excitation and emission over 600 nm enables Mg2+detection in live cells.


2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Upendar Reddy Gandra ◽  
Raphael Courjaret ◽  
Khaled Machaca ◽  
Mohammed Al-Hashimi ◽  
Hassan S. Bazzi

Abstract There a few reports of rhodamine-based fluorescent sensors for selective detection of only Al3+, due to the challenge of identifying a suitable ligand for binding Al3+ ion. The use of fluorophore moieties appended to a polymer backbone for sensing applications is far from mature. Here, we report a new fluorescent probe/monomer 4 and its ROMP derived polymer P for specific detection of Al3+ ions. Both monomer 4 and its polymer P exhibit high selectivity toward only Al3+ with no interference from other metal ions, having a limit detection of 0.5 and 2.1 µM, respectively. The reversible recognition of monomer 4 and P for Al3+ was also proved in presence of Na2EDTA by both UV–Vis and fluorometric titration. The experimental data indicates the behavior of 4 and P toward Al3+ is pH independent in medium conditions. In addition, the switch-on luminescence response of 4 at acidic pH (0 < 5.0), allowed us to specifically stain lysosomes (pH ~ 4.5–5.0) in live cells.


2021 ◽  
Author(s):  
Jiahui Du ◽  
Bing Zhao ◽  
Wei Kan ◽  
Haochun Yin ◽  
Tianshu Song ◽  
...  

Development of highly sensitive and selective fluorescent sensors toward Cu2+ has gained considerable attention in view of its application of environmental and biological fields. However, the strategy of sensing by...


2021 ◽  
Vol 1157 ◽  
pp. 338394
Author(s):  
Xiao-Yue Tang ◽  
Yi-Ming Liu ◽  
Xiao-Lin Bai ◽  
Hao Yuan ◽  
Yi-Kao Hu ◽  
...  

Molecules ◽  
2021 ◽  
Vol 26 (13) ◽  
pp. 3825
Author(s):  
Ling-Yi Shen ◽  
Xiao-Li Chen ◽  
Xian-Jiong Yang ◽  
Hong Xu ◽  
Ya-Li Huang ◽  
...  

A novel turn-on fluorescence probe L has been designed that exhibits high selectivity and sensitivity with a detection limit of 9.53 × 10−8 mol/L for the quantification of Zn2+. 1H-NMR spectroscopy and single crystal X-ray diffraction analysis revealed the unsymmetrical nature of the structure of the Schiff base probe L. An emission titration experiment in the presence of different molar fractions of Zn2+ was used to perform a Job’s plot analysis. The results showed that the stoichiometric ratio of the complex formed by L and Zn2+ was 1:1. Moreover, the molecular structure of the mononuclear Cu complex reveals one ligand L coordinates with one Cu atom in the asymmetric unit. On adding CuCl2 to the ZnCl2/L system, a Cu-Zn complex was formed and a strong quenching behavior was observed, which inferred that the Cu2+ displaced Zn2+ to coordinate with the imine nitrogen atoms and hydroxyl oxygen atoms of probe L.


2019 ◽  
Vol 55 (12) ◽  
pp. 1758-1761 ◽  
Author(s):  
Jun-Bin Li ◽  
Qianqian Wang ◽  
Hong-Wen Liu ◽  
Xia Yin ◽  
Xiao-Xiao Hu ◽  
...  
Keyword(s):  
Turn On ◽  

A turn-on bioluminescent probe (BP-HNO) that is free of autofluorescence for bioimaging nitroxyl in live cells and mice is reported for the first time.


2015 ◽  
Vol 44 (9) ◽  
pp. 4123-4132 ◽  
Author(s):  
Chirantan Kar ◽  
Soham Samanta ◽  
Sudeep Goswami ◽  
Aiyagari Ramesh ◽  
Gopal Das

Selective recognition of Al3+and Cd2+by UV-Vis and fluorescence based techniques using a cinnamaldehyde functionalized conjugated ligand, and its applications in paper strip and live cell imaging.


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