Synthesis of Janus Au nanorods/polydivinylbenzene hybrid nanoparticles for chemo-photothermal therapy

2018 ◽  
Vol 6 (16) ◽  
pp. 2481-2488 ◽  
Author(s):  
Yanming Wang ◽  
Xin Ji ◽  
Peng Pang ◽  
Yunfeng Shi ◽  
Jian Dai ◽  
...  
Keyword(s):  
Photothermal Therapy ◽  
Dispersion Polymerization ◽  
Drug Loading ◽  
Hybrid Nanoparticles ◽  
Loading Capacity ◽  
Au Nanorods ◽  
Seeded Dispersion Polymerization ◽  
Photothermal Effects

Janus hybrid nanoparticles synthesized through seeded dispersion polymerization show excellent drug loading capacity and chemo-photothermal effects for anti-tumour treatment.

Facile fabrication of polydopamine nanotubes for combined chemo-photothermal therapy

2019 ◽  
Vol 7 (43) ◽  
pp. 6828-6839 ◽  
Author(s):  
Yuzhe Sun ◽  
Edward W. Davis
Keyword(s):  
Photothermal Therapy ◽  
Drug Loading ◽  
Loading Capacity ◽  
Facile Fabrication

Polydopamine nanoparticles with higher drug loading capacity and enhanced photothermal behavior.

Design of dual-responsive nanocarries with high drug loading capacity based on hollow mesoporous organosilica nanoparticles

2019 ◽  
Vol 233 ◽  
pp. 230-235 ◽  
Author(s):  
Li-li Lu ◽  
Wen-ya Xiong ◽  
Jun-bin Ma ◽  
Tian-fang Gao ◽  
Si-yuan Peng ◽  
...  
Keyword(s):  
Drug Loading ◽  
Loading Capacity ◽  
High Drug ◽  
Dual Responsive ◽  
Mesoporous Organosilica ◽  
High Drug Loading

Present trends in the encapsulation of anticancer drugs

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Xavier Montané ◽  
Karolina Matulewicz ◽  
Karolina Balik ◽  
Paulina Modrakowska ◽  
Marcin Łuczak ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Drug Toxicity ◽  
Recent Progress ◽  
Polymeric Micelles ◽  
Drug Loading ◽  
The Body ◽  
Inorganic Nanoparticles ◽  
Hybrid Nanoparticles ◽  
Traditional Medicines ◽  
Low Solubility

Abstract Different nanomedicine devices that were developed during the recent years can be suitable candidates for their application in the treatment of various deadly diseases such as cancer. From all the explored devices, the nanoencapsulation of several anticancer medicines is a very promising approach to overcome some drawbacks of traditional medicines: administered dose of the drugs, drug toxicity, low solubility of drugs, uncontrolled drug delivery, resistance offered by the physiological barriers in the body to drugs, among others. In this chapter, the most important and recent progress in the encapsulation of anticancer medicines is examined: methods of preparation of distinct nanoparticles (inorganic nanoparticles, dendrimers, biopolymeric nanoparticles, polymeric micelles, liposomes, polymersomes, carbon nanotubes, quantum dots, and hybrid nanoparticles), drug loading and drug release mechanisms. Furthermore, the possible applications in cancer prevention, diagnosis, and cancer therapy of some of these nanoparticles have been highlighted.

scholarly journals Exploring the drug loading mechanism of photoresponsive inorganic nanocarriers through molecular dynamics simulations

Nanoscale ◽  
2021 ◽  
Author(s):  
Stefano Motta ◽  
Paulo Siani ◽  
Andrea Levy ◽  
Cristiana Di Valentin
Keyword(s):  
Molecular Dynamics ◽  
Molecular Dynamics Simulations ◽  
Combine Therapy ◽  
Drug Loading ◽  
Drug Carriers ◽  
Inorganic Nanoparticles ◽  
Loading Capacity ◽  
Physical Stimuli ◽  
Dynamics Simulations

Inorganic nanoparticles are gaining increasing attention as drug carriers because they respond to external physical stimuli, allowing to combine therapy with diagnosis. Their drawback is a low drug loading capacity,...

Photostable Iodinated Silica/Porphyrin Hybrid Nanoparticles with Heavy-Atom Effect for Wide-Field Photodynamic/Photothermal Therapy Using Single Light Source

2013 ◽  
Vol 24 (4) ◽  
pp. 503-513 ◽  
Author(s):  
Koichiro Hayashi ◽  
Michihiro Nakamura ◽  
Hirokazu Miki ◽  
Shuji Ozaki ◽  
Masahiro Abe ◽  
...  
Keyword(s):  
Light Source ◽  
Photothermal Therapy ◽  
Heavy Atom ◽  
Hybrid Nanoparticles ◽  
Wide Field ◽  
Heavy Atom Effect ◽  
Atom Effect

Preparation of poly(ionic liquid) composite particles and function modification with anion exchange

RSC Advances ◽  
2016 ◽  
Vol 6 (37) ◽  
pp. 31574-31579 ◽  
Author(s):  
Masayoshi Tokuda ◽  
Tatsunori Shindo ◽  
Toyoko Suzuki ◽  
Hideto Minami
Keyword(s):  
Ionic Liquid ◽  
Anion Exchange ◽  
Dispersion Polymerization ◽  
Composite Particles ◽  
Seeded Dispersion Polymerization ◽  
Poly Ionic Liquid ◽  
And Function ◽  
Property Modification

Detailed investigation on the synthesis of poly(ionic liquid) composite particles by seeded (dispersion) polymerization and property modification using anion exchange.

scholarly journals On the Drug-Loading Capacity of Pectin Powder for Direct Compression

2012 ◽  
Vol 13 (2) ◽  
pp. 601-604
Author(s):  
Ingunn Tho ◽  
Katharina Picker-Freyer ◽  
Linda Salbu ◽  
Annette Bauer-Brandl
Keyword(s):  
Drug Loading ◽  
Direct Compression ◽  
Loading Capacity

scholarly journals Cancer Nanomedicines Stabilized by π-π Stacking between Heterodimeric Prodrugs Enable Exceptionally High Drug Loading Capacity and Safer Delivery of Drug Combinations

Theranostics ◽  
2017 ◽  
Vol 7 (15) ◽  
pp. 3638-3652 ◽  
Author(s):  
Hangxiang Wang ◽  
Jianmei Chen ◽  
Chang Xu ◽  
Linlin Shi ◽  
Munire Tayier ◽  
...  
Keyword(s):  
Drug Loading ◽  
Drug Combinations ◽  
Loading Capacity ◽  
High Drug ◽  
Π Stacking ◽  
High Drug Loading

scholarly journals Synthesis of pH-Sensitive and Self-Fluorescent Polymeric Micelles Derived From Rosin and Vegetable Oils via ATRP

2021 ◽  
Vol 9 ◽  
Author(s):  
Juan Yu ◽  
Chaoqun Xu ◽  
Chuanwei Lu ◽  
Qian Liu ◽  
Jifu Wang ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Vegetable Oils ◽  
Renewable Resources ◽  
Polymeric Micelles ◽  
Drug Loading ◽  
Dehydroabietic Acid ◽  
Great Promise ◽  
Loading Capacity ◽  
Carboxylic Groups ◽  
Ph Dependent

Preparation and application of sustainable polymers derived from renewable resources are of great significance. The aim of this study is to synthesize a kind of sustainable polymeric micelles from rosin and vegetable oils via atom transfer radical polymerization (ATRP) and to investigate the doxorubicin delivery properties of these micelles. Dehydroabietic acid–based poly lauryl methacrylate (DA-PLMA) with narrow PDI of 1.13 was prepared in a well-controlled process using rosin as an ATRP initiator. Thereafter, carboxylic groups were introduced to form poly methacrylic acid (PMAA) moieties in DA-PLMA polymer via acid hydrolysis. The resulted DA-PLMA-PMAA could self-assemble in water to form pH-dependent polymeric micelles with a diameter of ∼65 nm and PDI as low as 0.105. Owing to the existence of rosin, DA-PLMA-PMAA micelles also showed self-fluorescence properties. In addition, Dox-loaded micelles were prepared in aqueous solution with the drug-loading capacity as high as 16.0% and showed sustained-release characteristics. These results demonstrate great promise for designing polymeric micellar from rosin and vegetable oils.

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