Dual-functional carbon dot-labeled heavy-chain ferritin for self-targeting bio-imaging and chemo-photodynamic therapy

2018 ◽  
Vol 6 (19) ◽  
pp. 3107-3115 ◽  
Author(s):  
Hanchun Yao ◽  
Weiwei Zhao ◽  
Suge Zhang ◽  
Xiaofang Guo ◽  
Ying Li ◽  
...  

Dual-functional carbon dots were synthesized for bio-imaging and photodynamic therapy; HFn(DOX)/CDs were used for simultaneous imaging and chemo-photodynamic therapy.

2021 ◽  
Vol 9 (4) ◽  
pp. 1232-1236
Author(s):  
Yujie Zhang ◽  
Wendi Huang ◽  
Xueying Tan ◽  
Jinhui Wang ◽  
Yufen Zhao ◽  
...  

A mitochondria-targeted dual-functional aggregation-induced emission luminogen, TPP-TPEDCH, was rationally designed and developed for intracellular mitochondrial imaging and photodynamic therapy.


RSC Advances ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 2253-2291
Author(s):  
Amin Shiralizadeh Dezfuli ◽  
Elmira Kohan ◽  
Sepand Tehrani Fateh ◽  
Neda Alimirzaei ◽  
Hamidreza Arzaghi ◽  
...  

Organic dots is a term used to represent materials including graphene quantum dots and carbon quantum dots because they rely on the presence of other atoms (O, H, and N) for their photoluminescence or fluorescence properties. Cargo delivery, bio-imaging, photodynamic therapy and photothermal therapy are major biomedical applications of organic dots.


2020 ◽  
Vol 3 (1) ◽  
pp. 15
Author(s):  
César Ray ◽  
Andrés García-Sampedro ◽  
Christopher Schad ◽  
Edurne Avellanal-Zaballa ◽  
Florencio Moreno ◽  
...  

A new approach for the rapid multi-functionalization of BODIPY dyes towards biophotonics is reported. It is based on novel N-BODIPYs, through reactive intermediates with alkynyl groups to be further derivatized by click chemistry. This approach has been exemplified by the development of new dyes for cell bio-imaging, which have proven to successfully internalize into pancreatic cancer cells and accumulate in the mitochondria. The in vitro suitability for photodynamic therapy (PDT) was also analyzed and confirmed our compounds to be promising PDT candidates for the treatment of pancreatic cancer.


The Analyst ◽  
2020 ◽  
Vol 145 (3) ◽  
pp. 1056-1061 ◽  
Author(s):  
Yali Yang ◽  
Haijuan Zhang ◽  
Jia Chen ◽  
Zhan Li ◽  
Liang Zhao ◽  
...  

Red emitting carbon dots derived from p-phenylenediamine were successfully grafted onto the surface of porous silica spheres which served as a new stationary phase for hydrophilic interaction chromatography with enhanced selectivity.


RSC Advances ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 1282-1286
Author(s):  
Zhang Jiayin ◽  
Wang Qiyu ◽  
Liang Hong ◽  
Song Guoli ◽  
Zhang Zhiguo

An optimal Tm3+ concentration of approximately 1% was determined for the most efficient energy distribution to balance imaging and PDT.


2018 ◽  
Vol 4 (1) ◽  
pp. 19 ◽  
Author(s):  
Selvy Uftovia Hepriyadi ◽  
. Isnaeni

Fluorescence materials such as carbon dots are unique and non-toxic materials that can be produced using many methods. In this research, synthesis and optical characterization of carbon dots from the peels of dragon fruit and pear have been done. The synthesis uses bottom-up method using microwave with 20 minutes, 40 minutes, and 80 minutes of heating time. The result of optical characterizations showed that the samples that have been heat treated are carbon dots based of the absorbance in the range of 280-350 nm, and the intensity are decreased in the range of visible and infrared wavelength. There are emission and intensity changes by different heat treatments. From the samples of dragon fruit's peels, the emission wavelength tended to shift toward visible light at the wavelength of 551.51 nm, 507.98 nm and 487.28 nm with the excitation at the wavelength of 420 nm from pulsed pico-laser. While, the emission wavelength from the samples of pears peels were fluctuate in wavelength of 529.09 nm, 507.52 nm and 519.46 nm. Similarly, the time-resolved photoluminescence characterization test showed that there were time changes in each sample of carbon dot. The decay lifetime of carbon dots was fluctuated between 4.5 ns - 5.4 ns for dragon fruit’s peels and about 1.9 ns - 2.4 ns for pear's peels.


2021 ◽  
Author(s):  
Shreya Bhatt ◽  
Gaurav Vyas ◽  
Parimal Paul

Preparation of water dispersible carbon dots from inexpensive natural carbon precursors and its application for purposes such as sensing, bio-imaging, patterning agent etc. is showing growing interest in recent years....


Nanoscale ◽  
2021 ◽  
Author(s):  
Parinaz Fathi ◽  
Parikshit Moitra ◽  
Madeleine M. McDonald ◽  
Mandy Brigitte Esch ◽  
Dipanjan Pan

Carbon dots are biocompatible nanoparticles suitable for a variety of biomedical applications. Careful selection of carbon dot precursors and surface modification techniques has allowed for the development of carbon dots...


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