scholarly journals An integrated-molecular-beacon based multiple exponential strand displacement amplification strategy for ultrasensitive detection of DNA methyltransferase activity

2019 ◽  
Vol 10 (8) ◽  
pp. 2290-2297 ◽  
Author(s):  
Yun-Xi Cui ◽  
Xue-Nan Feng ◽  
Ya-Xin Wang ◽  
Hui-Yu Pan ◽  
Hua Pan ◽  
...  
Keyword(s):  
Signal Amplification ◽  
Dna Methyltransferase ◽  
Molecular Beacon ◽  
Ultrasensitive Detection ◽  
Strand Displacement ◽  
Methyltransferase Activity ◽  
Strand Displacement Amplification ◽  
Multiple Signal ◽  
Amplification Strategy

An ultra-sensitive biosensor using only two DNA oligos to initiate multiple signal amplification cycles.

Label-free molecular beacon-based quadratic isothermal exponential amplification: a simple and sensitive one-pot method to detect DNA methyltransferase activity

2015 ◽  
Vol 51 (70) ◽  
pp. 13538-13541 ◽  
Author(s):  
Qingwang Xue ◽  
Lei Wang ◽  
Wei Jiang
Keyword(s):  
Dna Methyltransferase ◽  
Molecular Beacon ◽  
Label Free ◽  
Methyltransferase Activity ◽  
One Pot ◽  
Amplification Strategy

An illustration of the label-free molecular beacon-mediated quadratic isothermal exponential amplification strategy (LFMB-QIEA) for target Dam MTase detection.

A novel DNA biosensor for ultrasensitive detection of DNA methyltransferase activity based on a high-density “hot spots” SERS substrate and rolling circle amplification strategy

The Analyst ◽  
2021 ◽  
Author(s):  
Shengjie Ge ◽  
Menglin Ran ◽  
Yu Mao ◽  
Yue Sun ◽  
Xinyu Zhou ◽  
...  
Keyword(s):  
Hot Spots ◽  
Dna Methyltransferase ◽  
Rolling Circle Amplification ◽  
High Density ◽  
Dna Biosensor ◽  
Ultrasensitive Detection ◽  
Sers Substrate ◽  
Methyltransferase Activity ◽  
Rolling Circle ◽  
Amplification Strategy

Herein, we proposed a novel biosensor based on the high-density “hot spots” Au@SiO2 array substrate and rolling circle amplification (RCA) strategy for ultrasensitive detection of the CpG methyltransferase (M.SssI) activity....

Invasive reaction assisted strand-displacement signal amplification for sensitive DNA detection

2014 ◽  
Vol 50 (89) ◽  
pp. 13722-13724 ◽  
Author(s):  
Bingjie Zou ◽  
Qinxin Song ◽  
Jianping Wang ◽  
Yunlong Liu ◽  
Guohua Zhou
Keyword(s):  
Signal Amplification ◽  
Molecular Beacon ◽  
Dna Detection ◽  
Strand Displacement ◽  
Strand Displacement Amplification ◽  
Displacement Signal

An extension-block base in a molecular beacon enables beacon-assisted strand-displacement amplification to couple with invasive reaction efficiently by flap extension.

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