scholarly journals A copper-catalyzed double coupling enables a 3-step synthesis of the quassinoid core architecture

2019 ◽  
Vol 10 (3) ◽  
pp. 768-772 ◽  
Author(s):  
Matthew L. Condakes ◽  
Rachel Z. Rosen ◽  
Stephen J. Harwood ◽  
Thomas J. Maimone
Keyword(s):  
Anticancer Activity ◽  
Cross Coupling ◽  
Tandem Reaction ◽  
Double Coupling

A cross coupling/SN2′ tandem reaction is described to construct the polycyclic core architecture of the quassinoids, a fascinating class of degraded triterpenes with potent anticancer activity.

Synthesis of dibenzo[a,c]carbazoles from 2-(2-halophenyl)-indoles and iodobenzenes via palladium-catalyzed dual C–H functionalization

2017 ◽  
Vol 15 (32) ◽  
pp. 6808-6812 ◽  
Author(s):  
Lijun Wu ◽  
Guobo Deng ◽  
Yun Liang
Keyword(s):  
Cross Coupling ◽  
Tandem Reaction ◽  
Efficient Approach ◽  
Palladium Catalyzed

We report an efficient approach to synthesize dibenzo[a,c]carbazoles via a palladium-catalyzed cross-coupling tandem reaction.

scholarly journals Synthesis of Piceatannol, an Oxygenated Analog of Resveratrol

2016 ◽  
Vol 11 (7) ◽  
pp. 1934578X1601100
Author(s):  
Takuya Tashiro ◽  
Shinobu Honzawa ◽  
Takumichi Sugihara
Keyword(s):  
Anticancer Activity ◽  
Red Wine ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Beneficial Effects ◽  
Naturally Occurring ◽  
Cross Coupling Reaction ◽  
Trans Stilbene ◽  
Acid Catalyzed

Piceatannol (3,3′,4,5′-tetrahydroxy- trans-stilbene, 2), an oxygenated analog of resveratrol (1), was synthesized. It is one of the naturally occurring polyphenolic stilbenoids contained in red wine, and possesses many kinds of beneficial effects such as anticancer activity. The trans-stilbene skeleton of 2 was constructed by Pd-catalyzed Suzuki-Miyaura cross coupling reaction of triflate 8 with ( E)-alkenylboronoate 13. The key intermediate 13 was prepared diastereoselectively by acid-catalyzed hydroboration of pinacolborane 12 to alkyne 11.

ChemInform Abstract: Aqueous C-S Cross-Coupling: Synthesis of 2-Iminobenzo-1,3-oxathioles via CuCl2·H2O-Catalyzed Tandem Reaction of 2-Iodophenols with Isothiocyanates.

ChemInform ◽  
2011 ◽  
Vol 42 (29) ◽  
pp. no-no
Author(s):  
Qiuping Ding ◽  
Xianjin Liu ◽  
Banpeng Cao ◽  
Zhenzhen Zong ◽  
Yiyuan Peng
Keyword(s):  
Cross Coupling ◽  
Tandem Reaction

Copper-catalyzed cross-coupling and sequential allene-mediated cyclization for the synthesis of 1,2,3-triazolo[1,5-a]quinolines

2020 ◽  
Vol 18 (36) ◽  
pp. 7174-7182
Author(s):  
Jianhua Yang ◽  
Shaoqi Xiong ◽  
Yongsheng Ren ◽  
Tiebo Xiao ◽  
Yubo Jiang
Keyword(s):  
Cross Coupling ◽  
Tandem Reaction

In this paper, a tandem reaction involving copper-catalyzed cross-coupling and allene-mediated cyclization of 1-(2-ethynylaryl)-1,4-disubstituted-1,2,3-triazole with N-tosylhydrazone has been developed.

scholarly journals Catalyst-controlled regiodivergent ring-opening C(sp3)–Si bond-forming reactions of 2-arylaziridines with silylborane enabled by synergistic palladium/copper dual catalysis

2019 ◽  
Vol 10 (37) ◽  
pp. 8642-8647 ◽  
Author(s):  
Youhei Takeda ◽  
Kaoru Shibuta ◽  
Shohei Aoki ◽  
Norimitsu Tohnai ◽  
Satoshi Minakata
Keyword(s):  
Ring Opening ◽  
Cross Coupling ◽  
Tandem Reaction ◽  
Bond Forming ◽  
Bond Forming Reactions ◽  
Cu Catalyst ◽  
Dual Catalysis

A Pd/Cu catalyst-controlled regiodivergent and stereospecific ring-opening C(sp3)–Si cross-coupling of 2-arylaziridines with silylborane has been developed and a new tandem reaction to give another regioisomer of silylamine has been discovered.

Aqueous C–S cross-coupling: synthesis of 2-iminobenzo-1,3-oxathioles via CuCl2·H2O-catalyzed tandem reaction of 2-iodophenols with isothiocyanates

2011 ◽  
Vol 52 (16) ◽  
pp. 1964-1967 ◽  
Author(s):  
Qiuping Ding ◽  
Xianjin Liu ◽  
Banpeng Cao ◽  
Zhenzhen Zong ◽  
Yiyuan Peng
Keyword(s):  
Cross Coupling ◽  
Tandem Reaction
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