scholarly journals Genetically encoded tags for real time dissection of protein assembly in living cells

2018 ◽  
Vol 9 (25) ◽  
pp. 5551-5555 ◽  
Author(s):  
Guolin Ma ◽  
Qian Zhang ◽  
Lian He ◽  
Nhung T. Nguyen ◽  
Shuzhong Liu ◽  
...  
Keyword(s):  
Protein Structure ◽  
Real Time ◽  
Protein Assembly ◽  
Living Cells ◽  
Protein Target ◽  
Physiological Conditions

Genetically encoded tags (MoTags) to assess protein oligomeric states, probe protein structure and monitor protein–target interactions under physiological conditions in cellulo.

Real-Time Investigation of Engineered Nanomaterials Cytotoxicity in Living Alveolar Epithelia with Hopping Probe Ion Conductance Microscopy

2013 ◽  
Vol 651 ◽  
pp. 24-28 ◽  
Author(s):  
Xiao Liu ◽  
Hui Zhu ◽  
Hu Jie Lu ◽  
Ying Li ◽  
Jian Ning Zhang ◽  
...  
Keyword(s):  
Real Time ◽  
Imaging Techniques ◽  
Living Cells ◽  
Alveolar Epithelial Cells ◽  
Engineered Nanomaterials ◽  
Ion Conductance ◽  
Physiological Conditions ◽  
Alveolar Epithelial ◽  
Ideal Tool ◽  
Topographic Imaging

Widely used engineered nanomaterials (NMs) display unique properties that may have impact on human health, and thus require a reliable evaluation of their potential cytotoxicity. There is a continuing need for real-time imaging techniques capable of studying the interactions between NMs and living alveolar epithelial cells under physiological conditions. A new developed noninvasive HPICM is designed for continuous high-resolution topographic imaging of living cells, which makes it an ideal tool to study NMs cytotoxicity in living alveolar epithelia by performing reliable repetitive scanning. In this review, we concisely introduced the operation principle of HPICM and its applications to real-time investigation of engineered NMs cytotoxicity in living alveolar epithelia. Published results demonstrate that non-contact HPICM combined with patch-clamp has the potential to become a powerful microscopy for real-time studies of NM-cell interactions under physiological conditions.

A multicolor DNA tetrahedron nanoprobe for analyzing human telomerase in living cells

2021 ◽  
Author(s):  
Ruiyuan Zhang ◽  
Ruixue Zhang ◽  
Wei Jiang ◽  
Xiaowen Xu
Keyword(s):  
Real Time ◽  
Length Distribution ◽  
Telomerase Activity ◽  
Living Cells ◽  
Real Time Monitoring ◽  
Dna Tetrahedron ◽  
Human Telomerase

A sequentially lighting-up multicolor DNA tetrahedron nanoprobe is constructed for imaging telomerase activity, real-time monitoring telomerase action and determining product length distribution in living cells.

scholarly journals Systematic Review on Human Skin-Compatible Wearable Photoplethysmography Sensors

2021 ◽  
Vol 11 (5) ◽  
pp. 2313
Author(s):  
Inho Lee ◽  
Nakkyun Park ◽  
Hanbee Lee ◽  
Chuljin Hwang ◽  
Joo Hee Kim ◽  
...  
Keyword(s):  
Systematic Review ◽  
Health Care ◽  
Real Time ◽  
Human Skin ◽  
State Of The Art ◽  
Electronic Devices ◽  
Semiconducting Materials ◽  
Physiological Conditions ◽  
Technological Developments ◽  
Monitoring Technologies

The rapid advances in human-friendly and wearable photoplethysmography (PPG) sensors have facilitated the continuous and real-time monitoring of physiological conditions, enabling self-health care without being restricted by location. In this paper, we focus on state-of-the-art skin-compatible PPG sensors and strategies to obtain accurate and stable sensing of biological signals adhered to human skin along with light-absorbing semiconducting materials that are classified as silicone, inorganic, and organic absorbers. The challenges of skin-compatible PPG-based monitoring technologies and their further improvements are also discussed. We expect that such technological developments will accelerate accurate diagnostic evaluation with the aid of the biomedical electronic devices.

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