scholarly journals Hair growth promotion effect of cedrol cream and its dermatopharmacokinetics

RSC Advances ◽  
2018 ◽  
Vol 8 (73) ◽  
pp. 42170-42178 ◽  
Author(s):  
Yan Zhang ◽  
Jie-wen Wang ◽  
Fan-zhi Qu ◽  
Yu-meng Zhang ◽  
Guang-yue Su ◽  
...  
Keyword(s):  
Beneficial Effect ◽  
Hair Loss ◽  
Hair Growth ◽  
Growth Promotion ◽  
Promotion Effect

Topical use of cedrol ethanol has been reported to have a beneficial effect on hair loss.

scholarly journals Hair Growth Promotion by Extracts of Inula Helenium and Caesalpinia Sappan Bark in Patients with Androgenetic Alopecia: A Pre-clinical Study Using Phototrichogram Analysis

Cosmetics ◽  
2019 ◽  
Vol 6 (4) ◽  
pp. 66
Author(s):  
Hyoung Chul Choi ◽  
Gae Won Nam ◽  
Noh Hee Jeong ◽  
Bu Young Choi
Keyword(s):  
Clinical Study ◽  
Hair Loss ◽  
Hair Growth ◽  
Blood Circulation ◽  
Growth Promotion ◽  
Test Group ◽  
Androgenetic Alopecia ◽  
Hair Density ◽  
Caesalpinia Sappan ◽  
Inula Helenium

Inula helenium (IH) is known to possess antifungal, anti-bacterial, anti-helminthic, and anti-proliferation activities. Caesalpinia Sappan (CS) is known to reduce inflammation and improve blood circulation. Based on their folkloric use, these plants are expected to be promising candidates for promoting hair growth and preventing hair loss. Moreover, these plants are rich sources of certain phytochemicals, which have been reported to promote hair growth. In this clinical trial, we investigate the efficacy of a scalp shampoo formulated by mixing extracts of IH and CS in preventing hair loss and promoting hair growth in patients with androgenetic alopecia. Using a phototrichogram (Folliscope 2.8, LeadM, Korea), we compared the hair density and total hair counts in patients receiving the scalp shampoo at baseline, and at 8, 16, and 24 weeks after use of the shampoo. We found a statistically significant increase in the total hair count in the test group (n = 23) after 16 and 24 weeks of using the scalp shampoo (2.17 n/cm2 ± 5.72, p < 0.05; and 4.30 n/cm2 ± 6.37, p < 0.01, respectively) as compared to the control subjects. Based on the results of this clinical study, we conclude that the IH and CS extract complex is a promising remedy for preventing hair loss and promoting hair growth.

scholarly journals Comparative Hair Restorer Efficacy of Medicinal Herb on Nude (Foxn1nu) Mice

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Shahnaz Begum ◽  
Mi Ra Lee ◽  
Li Juan Gu ◽  
Md. Jamil Hossain ◽  
Hyun Kyoung Kim ◽  
...  
Keyword(s):  
Panax Ginseng ◽  
Nude Mice ◽  
Hair Loss ◽  
Hair Growth ◽  
Growth Promotion ◽  
Hair Follicles ◽  
Growth Potential ◽  
Eclipta Alba ◽  
Growth Area ◽  
Brdu Labeling

Eclipta alba(L.) Hassk,Asiasarum sieboldii(Miq.) F. Maek (Asiasari radix), andPanax ginsengC. A. Mey (red ginseng) are traditionally acclaimed for therapeutic properties of various human ailments. Synergistic effect of each standardized plant extract was investigated for hair growth potential on nude mice, as these mutant mice genetically lack hair due to abnormal keratinization. Dried plant samples were ground and extracted by methanol. Topical application was performed on the back of nude mice daily up to completion of two hair growth generations. The hair density and length ofEclipta albatreated mice were increased significantlyP>0.001than control mice. Hair growth area was also distinctly visible inEclipta albatreated mice. On the other hand,Asiasari radixandPanax ginsengtreated mice developing hair loss were recognized from the abortive boundaries of hair coverage. Histomorphometric observation of nude mice skin samples revealed an increase in number of hair follicles (HFs). The presence of follicular keratinocytes was confirmed by BrdU labeling, S-phase cells in HFs. Therefore,Eclipta albaextract and/or phytochemicals strongly displayed incomparability of hair growth promotion activity than others. Thus, the standardizedEclipta albaextract can be used as an effective, alternative, and complementary treatment against hair loss.

Ethnobotanical and Pharmacological Importance of the Herbal Plants With Anti-Hair Fall and Hair Growth Activities

2020 ◽  
pp. 49-66
Author(s):  
Kiran Mustafa ◽  
Javaria Kanwal ◽  
Sara Musaddiq ◽  
Samia Khakwani
Keyword(s):  
Natural Products ◽  
Medicinal Plants ◽  
Beneficial Effect ◽  
Hair Loss ◽  
Hair Growth ◽  
Active Constituent ◽  
Herbal Plants ◽  
Natural Plants

The primary aim of this study is to access the salient herbal plants with the active constituent of potentially anti-hair fall activities. It also presents the various reasons behind hair loss ailments. As part of this study, a focus is placed on active phytochemicals within these medicinal plants or natural products in terms of various hair fall disease treatments. As natural products have a beneficial effect to minimize hair loss and have promoted the potential for new hair growth, it presents the medicinal values of natural plants in reference to safety and effectiveness for health.

Ethnobotanical and Pharmacological Importance of the Herbal Plants With Anti-Hair Fall and Hair Growth Activities

2022 ◽  
pp. 62-75
Author(s):  
Kiran Mustafa ◽  
Javaria Kanwal ◽  
Sara Musaddiq ◽  
Samia Khakwani
Keyword(s):  
Natural Products ◽  
Medicinal Plants ◽  
Beneficial Effect ◽  
Hair Loss ◽  
Hair Growth ◽  
Active Constituent ◽  
Herbal Plants ◽  
Natural Plants

The primary aim of this study is to access the salient herbal plants with the active constituent of potentially anti-hair fall activities. It also presents the various reasons behind hair loss ailments. As part of this study, a focus is placed on active phytochemicals within these medicinal plants or natural products in terms of various hair fall disease treatments. As natural products have a beneficial effect to minimize hair loss and have promoted the potential for new hair growth, it presents the medicinal values of natural plants in reference to safety and effectiveness for health.

scholarly journals Visible-to-Near IR Quantum Dot–Based Hypermulticolor High-Content Screening of Herbal Medicines for the Efficacy Monitoring of Hair Growth Promotion and Hair Loss Inhibition

2012 ◽  
Vol 18 (4) ◽  
pp. 462-473 ◽  
Author(s):  
Min Jung Kim ◽  
Chaeyun Lim ◽  
Jun Young Lee ◽  
Kyung Ran Im ◽  
Kyung-Sup Yoon ◽  
...  
Keyword(s):  
Growth Factor ◽  
Herbal Medicine ◽  
Hair Loss ◽  
Hair Growth ◽  
Near Infrared ◽  
Transforming Growth Factor ◽  
Growth Promotion ◽  
Herbal Medicines ◽  
Extraction Methods ◽  
High Content Screening

There is a growing interest in alopecia prevention strategies, as the number of alopecia patients is increasing. We examine the efficacy of herbal medicine for hair growth promotion/hair loss inhibition in two cell lines via Western blot and high-content screening (HCS). Nine herbal extracts were obtained from three different herbal medicine mixtures using 3 different extraction methods. Five target proteins—IGF-1 (insulin-like growth factor–1), TGF-β2 (transforming growth factor–β2), VEGF (vascular endothelial growth factor), DKK-1 (Dickkopf-1), and Wnt5α—were observed for the assessment of hair growth promotion/hair loss inhibition efficacy. The efficacies of nine extracts were compared with minoxidil as control. Efficacy was defined as a rise in the expression levels of IGF-1, VEGF, and Wnt5α but a decrease in DKK-1 and TGF-β2. Intracellular concurrent imaging of these proteins was successfully achieved using HCS, employing visible-to-near infrared probing based on quantum-antibody conjugates and hypermulticolor imaging.

scholarly journals A Review on Hair Growth Regulator

2020 ◽  
Vol 10 (5) ◽  
pp. 368-375
Author(s):  
Manu Bharti ◽  
Alankar Shrivastav ◽  
M. Abid ◽  
Najam Ali Khan
Keyword(s):  
Side Effects ◽  
Medicinal Plants ◽  
Hair Loss ◽  
Hair Growth ◽  
Growth Promotion ◽  
Promoting Effect ◽  
Herbal Formulation ◽  
Growth Activity ◽  
Ancient Times ◽  
Growth Promoting

This review presents an overview on plants identified to possess hair growth activity in various ethno-botanical studies and surveys of tradition medicinal plants. There are various causes for hair loss and the phenomenon is still not fully understood. The treatments offered include both natural or synthetic products to treat the condition of hair loss (alopecia), nonetheless natural products are continuously gaining popularity mainly due to their fewer side effects and better formulation strategies for natural product extracts. Plants have been widely used for hair growth promotion since ancient times as reported in Ayurveda, Chinese and Unani systems of medicine. This review covers information about different herbs and herbal formulation that are believed to be able to reduce the rate of hair loss and at the same time stimulate new hair growth. A focus is placed on their mechanism of action and the review also covers various isolated phytoconstituents possessing hair growth promoting effect. Keywords: Alopecia, ayurveda, hair, herbal formulation.

Hair Growth in a Patient with Alopecia Areata on Tocilizumab

2021 ◽  
pp. 1-5
Author(s):  
Chloe J. Walker ◽  
Kelly E. Flanagan ◽  
James T. Pathoulas ◽  
Isabel Pupo Wiss ◽  
Maryanne M. Senna
Keyword(s):  
Monoclonal Antibody ◽  
Autoimmune Disease ◽  
Hair Loss ◽  
Alopecia Areata ◽  
Interleukin 6 ◽  
Hair Growth ◽  
Posterior Uveitis ◽  
Case Presentation ◽  
Antibody Targeting ◽  
Growth Changes

<b><i>Introduction:</i></b> Tocilizumab (TCZ), a recombinant humanized antihuman monoclonal antibody targeting interleukin-6 (IL-6) signaling, is often utilized in the management of autoimmune disease. Few reports have demonstrated hair growth changes in patients on TCZ. <b><i>Case Presentation:</i></b> Herein, we review the literature and report a 21-year-old woman with progressive alopecia areata (AA) presenting with AA improvement while on TCZ for concomitant posterior uveitis. <b><i>Discussion:</i></b> Our case demonstrates the potential ability of TCZ to disrupt IL-6 signaling involved in AA, leading to hair loss and regrowth.

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