scholarly journals Carbon quantum dots and their biomedical and therapeutic applications: a review

RSC Advances ◽  
2019 ◽  
Vol 9 (12) ◽  
pp. 6460-6481 ◽  
Author(s):  
Mohammad Jafar Molaei

The biomedical applications of the recently emerging carbon quantum dots are reviewed.

RSC Advances ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 2253-2291
Author(s):  
Amin Shiralizadeh Dezfuli ◽  
Elmira Kohan ◽  
Sepand Tehrani Fateh ◽  
Neda Alimirzaei ◽  
Hamidreza Arzaghi ◽  
...  

Organic dots is a term used to represent materials including graphene quantum dots and carbon quantum dots because they rely on the presence of other atoms (O, H, and N) for their photoluminescence or fluorescence properties. Cargo delivery, bio-imaging, photodynamic therapy and photothermal therapy are major biomedical applications of organic dots.


2018 ◽  
Vol 15 (2) ◽  
pp. 219-230 ◽  
Author(s):  
Inderbir SINGH ◽  
Riya ARORA ◽  
Hardik DHIMAN ◽  
Rakesh PAHWA

2021 ◽  
Vol 8 ◽  
Author(s):  
Nayab Azam ◽  
Murtaza Najabat Ali ◽  
Tooba Javaid Khan

Carbon quantum dots (CQDs) are a new type of nano-carbons that are currently favored over semiconductor quantum dots (QDs) because of their solubility, low toxicity, eco-friendliness, and cheap and facile synthesis giving desired optical characteristics. Moreover, their physiochemical properties can be controlled by their synthetic route. CQDs can emit fluorescence in the range from the UV to the near-infrared (NIR) region, making them suitable for biomedical applications. Fluorescence in these nano-carbon atoms can be tuned by varying the excitation wavelength. As of now, CQDs have been used in various applications such as in bioimaging, biosensing, electrochemical biosensing, drug delivery, gene delivery, photodynamic therapy in the treatment of cancers, pharmaceutical formulations, and treating inflammation. This article highlights the current progress and advancement of CQDs with focus on their synthetic routes, chemical and optical properties, and biomedical applications along with new perceptions in this interesting and promising field.


Author(s):  
Xianglin Cao ◽  
Jianjun Chen ◽  
Dandan Sun ◽  
Han Cui ◽  
Chenyang Rao ◽  
...  

The potential toxicity of carbon quantum dots (CQDs) has received much attention because of increasing biomedical applications. However, the impacts of CQD on the gut–liver axis and gut microbiota of...


2018 ◽  
Vol 11 (3) ◽  
pp. 431-443
Author(s):  
郭振振 GUO Zhen-zhen ◽  
唐玉国 TANG Yu-guo ◽  
孟凡渝 MENG Fan-yu ◽  
李 力 LI Li ◽  
杨大威 YANG Da-wei

2015 ◽  
Vol 17 (7) ◽  
pp. 3791-3797 ◽  
Author(s):  
Al-Mahmnur Alam ◽  
Byung-Yong Park ◽  
Zafar Khan Ghouri ◽  
Mira Park ◽  
Hak-Yong Kim

The synthesis of luminescent and biocompatible carbon quantum dots is demonstrated from cabbage, a new carbonaceous biomaterial, for bio-imaging.


Nanomaterials ◽  
2019 ◽  
Vol 9 (2) ◽  
pp. 274 ◽  
Author(s):  
Łukasz Janus ◽  
Marek Piątkowski ◽  
Julia Radwan-Pragłowska ◽  
Dariusz Bogdał ◽  
Dalibor Matysek

Rapid development in medicine and pharmacy has created a need for novel biomaterials with advanced properties such as photoluminescence, biocompability and long-term stability. The following research deals with the preparation of novel types of N-doped chitosan-based carbon quantum dots. Nanomaterials were obtained with simultaneous nitrogen-doping using biocompatible amino acids according to Green Chemistry principles. For the carbon quantum dots synthesis chitosan was used as a raw material known for its biocompability. The nanomaterials obtained in the form of lyophilic colloids were characterized by spectroscopic and spectrofluorimetric methods. Their quantum yields were determined. Additionally the cytotoxicity of the prepared bionanomaterials was evaluated by XTT (2,3-Bis-(2-methoxy-4-nitro5-sulfophenyl)-2H-tetrazolium-5-carboxanilide salt) method. Our results confirmed the formation of biocompatible quantum dots with carbon cores exhibiting luminescence in visible range. Performed studies showed that modification with lysine (11.5%) and glutamic acid (7.4%) had a high impact on quantum yield, whereas functionalization with amino acids rich in S and N atoms did not significantly increase in fluorescence properties. XTT assays as well as morphological studies on human dermal fibroblasts confirmed the lack of cytotoxicity of the prepared bionanomaterials. The study shows chitosan-based quantum dots to be promising for biomedical applications such as cell labelling, diagnostics or controlled drug delivery and release systems.


2020 ◽  
Vol 0 (4) ◽  
pp. 29-32
Author(s):  
B.M. GAREEV ◽  
◽  
A.M. ABDRAKHMANOV ◽  
G.L. SHARIPOV ◽  
◽  
...  

The photoluminescence of carbon quantum dots synthesized from natural honey and mixtures of honey and sugar has been studied. An increase in the sugar content leads to a decrease in the photoluminescence intensity without changing the shape of the luminescence spectrum of these quantum dots aqueous solutions, which is associated with a decrease in the yield of their synthesis in the sugar presence. The discovered effect can be used to detect sugar in honey. When examining five different market samples of flower honey using this method, two of them showed a significant decrease in the photoluminescence intensity. A laboratory test for compliance with GOST 19792-2017 Standard requirements established an excess of the sucrose content in these samples. Luminescent determination of sugar in honey does not require complicated equipment and can be used to develop a new analytical method for determining the sugar content in counterfeit natural honey.


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