scholarly journals Cholesterol-sensing role of phenylalanine in the interaction of human islet amyloid polypeptide with lipid bilayers

RSC Advances ◽  
2018 ◽  
Vol 8 (71) ◽  
pp. 40581-40588
Author(s):  
Ruijie Hao ◽  
Yang Li ◽  
Liping Guan ◽  
Tong Lu ◽  
Feihong Meng ◽  
...  
Keyword(s):  
Lipid Bilayers ◽  
Islet Amyloid Polypeptide ◽  
Human Islet ◽  
Islet Amyloid ◽  
Human Islet Amyloid Polypeptide

The interaction of hIAPP with cholesterol in the membrane is mediated by Phe15.

scholarly journals Role of Zinc in Human Islet Amyloid Polypeptide Aggregation

2010 ◽  
Vol 132 (26) ◽  
pp. 8973-8983 ◽  
Author(s):  
Jeffrey R. Brender ◽  
Kevin Hartman ◽  
Ravi Prakash Reddy Nanga ◽  
Nataliya Popovych ◽  
Roberto de la Salud Bea ◽  
...  
Keyword(s):  
Islet Amyloid Polypeptide ◽  
Human Islet ◽  
Islet Amyloid ◽  
Human Islet Amyloid Polypeptide

scholarly journals Analysis of the Role of the Conserved Disulfide in Amyloid Formation by Human Islet Amyloid Polypeptide in Homogeneous and Heterogeneous Environments

Biochemistry ◽  
2018 ◽  
Vol 57 (21) ◽  
pp. 3065-3074 ◽  
Author(s):  
Zachary Ridgway ◽  
Xiaoxue Zhang ◽  
Amy G. Wong ◽  
Andisheh Abedini ◽  
Ann Marie Schmidt ◽  
...  
Keyword(s):  
Islet Amyloid Polypeptide ◽  
Human Islet ◽  
Heterogeneous Environments ◽  
Amyloid Formation ◽  
Islet Amyloid ◽  
Human Islet Amyloid Polypeptide

Human Islet Amyloid Polypeptide Assembly: The Key Role of the 8–20 Fragment

2016 ◽  
Vol 120 (46) ◽  
pp. 11905-11911 ◽  
Author(s):  
Li Wang ◽  
Alexandre I. Ilitchev ◽  
Maxwell J. Giammona ◽  
Fei Li ◽  
Steven K. Buratto ◽  
...  
Keyword(s):  
Islet Amyloid Polypeptide ◽  
Human Islet ◽  
Islet Amyloid ◽  
Human Islet Amyloid Polypeptide

Human islet amyloid polypeptide accumulates at similar sites in islets of transgenic mice and humans

Diabetes ◽  
1994 ◽  
Vol 43 (5) ◽  
pp. 640-644 ◽  
Author(s):  
E. J. de Koning ◽  
J. W. Hoppener ◽  
J. S. Verbeek ◽  
C. Oosterwijk ◽  
K. L. van Hulst ◽  
...  
Keyword(s):  
Transgenic Mice ◽  
Islet Amyloid Polypeptide ◽  
Human Islet ◽  
Islet Amyloid ◽  
Human Islet Amyloid Polypeptide

scholarly journals The flanking peptides issue from the maturation of the human islet amyloid polypeptide (hIAPP) slightly modulate hIAPP-fibril formation but not hIAPP-induced cell death

Biochimie ◽  
2020 ◽  
Vol 170 ◽  
pp. 26-35 ◽  
Author(s):  
Shadai Salazar Vazquez ◽  
Bertrand Blondeau ◽  
Pierre Cattan ◽  
Mathieu Armanet ◽  
Ghislaine Guillemain ◽  
...  
Keyword(s):  
Cell Death ◽  
Islet Amyloid Polypeptide ◽  
Fibril Formation ◽  
Human Islet ◽  
Islet Amyloid ◽  
Human Islet Amyloid Polypeptide

scholarly journals Regulation of divalent metal ions to the aggregation and membrane damage of human islet amyloid polypeptide oligomers

RSC Advances ◽  
2021 ◽  
Vol 11 (21) ◽  
pp. 12815-12825
Author(s):  
Yajie Wang ◽  
Feihong Meng ◽  
Tong Lu ◽  
Chunyun Wang ◽  
Fei Li
Keyword(s):  
Metal Ions ◽  
Metal Binding ◽  
Membrane Damage ◽  
Islet Amyloid Polypeptide ◽  
Divalent Metal ◽  
Human Islet ◽  
Divalent Metal Ions ◽  
Islet Amyloid ◽  
Induced Membrane ◽  
Human Islet Amyloid Polypeptide

Their is a counteraction between a decrease in the disruptive ability of metal-associated oligomer species and an increase in the quantity of oligomers promoted by the metal binding in the activity of hIAPP induced membrane damage.

Sign in / Sign up

Export Citation Format

Share Document