scholarly journals A novel analytical method based on HPLC-PDA coupled post-column derivatization to evaluate the ability to inhibit tyrosine nitration in lotus leaf extracts

RSC Advances ◽  
2018 ◽  
Vol 8 (68) ◽  
pp. 38715-38720
Author(s):  
Yin Qian ◽  
Xi Chen ◽  
Jin Qi ◽  
Xuming Liu
Keyword(s):  
Analytical Method ◽  
Inhibitory Activity ◽  
Tyrosine Nitration ◽  
Leaf Extracts ◽  
Lotus Leaf

A novel analytical method based on HPLC-PDA coupled post-column derivatization to evaluate the inhibitory activity of tyrosine nitration in lotus leaf extracts.

scholarly journals α-Glucosidase inhibitory activity of compounds isolated from the twig and leaf extracts of Desmos dumosus

Heliyon ◽  
2021 ◽  
Vol 7 (2) ◽  
pp. e06180
Author(s):  
Virayu Suthiphasilp ◽  
Tharakorn Maneerat ◽  
Raymond J. Andersen ◽  
Brian O. Patrick ◽  
Stephen G. Pyne ◽  
...  
Keyword(s):  
Inhibitory Activity ◽  
Leaf Extracts

In Vitro HIV Type-1 Reverse Transcriptase Inhibitory Activity from Leaf Extracts ofScoparia dulcisL.

2009 ◽  
Vol 15 (3) ◽  
pp. 241-247 ◽  
Author(s):  
Mahendar Porika ◽  
Mahender Aileni ◽  
Venugopal Rao Kokkirala ◽  
Kranthi Gadidasu ◽  
Pavan Umate ◽  
...  
Keyword(s):  
Reverse Transcriptase ◽  
Inhibitory Activity ◽  
Leaf Extracts ◽  
Hiv Type 1

scholarly journals Phytochemical evaluation and in vitro antidiabetic efficiency of isopropanolic leaf extract of pimenta racemosa

2020 ◽  
Vol 7 (2) ◽  
pp. 50-55
Author(s):  
Anitha T A ◽  
Pakutharivu T ◽  
Nirubama K ◽  
Akshaya V
Keyword(s):  
Diabetes Mellitus ◽  
Glucose Uptake ◽  
Inhibitory Activity ◽  
Leaf Extract ◽  
Yeast Cells ◽  
Antidiabetic Activity ◽  
Leaf Extracts ◽  
Pimenta Racemosa

The traditional herbal medicines are mainly obtained from plants are used in the management of Diabetes mellitus. The main objective of this work was to assess the presence of phytochemical compounds and to evaluate the in vitro antidiabetic activity of isopropanolic extracts of Pimenta racemosa leaves by studying their α-amylase inhibitory activity and glucose transport across yeast cells. Screening of phytochemicals showed positive results for alkaloids, steroids, cardiac glycosides, terpenoids, reducing sugars, anthraquinones, and results of in vitro α-amylase inhibitory studies demonstrated there was a dose-dependent increase in percentage inhibitory activity by the isopropanolic leaf extracts of Pimenta racemosa. At a concentration of 1 mg/ml, the extract showed a percentage inhibition 33.6 and for 5 mg/ml it was 91.2. The glucose uptake study was also studied through yeast cells by analyzing theamount of glucose remaining in the medium after a specific time intervals. It serves as an indicator for the capability of isopropanolic leaf extracts of Pimenta racemosa to transport the glucose into yeast cells. As a result, we found that the isopropanolic leaf extract of Pimenta racemosa have inhibitory activity against αamylase and also, which is efficient in glucose uptake. This therapeutic potentiality of Pimenta racemosa could be exploited in the treatment of Type 2 Diabetes mellitus. Further studies are also required to elucidate whether the plant have antidiabetic potential by in vivo for corroborating the traditional claim of the plant.

scholarly journals Metabolite Profiling of Eastern Teaberry (Gaultheria procumbens L.) Lipophilic Leaf Extracts with Hyaluronidase and Lipoxygenase Inhibitory Activity

Molecules ◽  
2017 ◽  
Vol 22 (3) ◽  
pp. 412 ◽  
Author(s):  
Piotr Michel ◽  
Aleksandra Owczarek ◽  
Magdalena Matczak ◽  
Martyna Kosno ◽  
Paweł Szymański ◽  
...  
Keyword(s):  
Inhibitory Activity ◽  
Metabolite Profiling ◽  
Leaf Extracts ◽  
Gaultheria Procumbens

scholarly journals IN-VITROSTUDIES ON ANTIFUNGALACTIVITY OF SOMEMISTLETOE SPECIES

2021 ◽  
Vol 9 (06) ◽  
pp. 420-427
Author(s):  
R. Neelima ◽  
◽  
B. Sujatha ◽  
N.V. Ramana ◽  
B.V. Rao ◽  
...  
Keyword(s):  
Antifungal Activity ◽  
Ethyl Acetate ◽  
Phytophthora Infestans ◽  
Inhibitory Activity ◽  
Sclerotium Rolfsii ◽  
Diffusion Method ◽  
Disc Diffusion ◽  
Disc Diffusion Method ◽  
Leaf Extracts

In vitro evaluation of antifungal activity by disc diffusion method was carried out on leaf extracts of D.falcata, D. falcata var pubescens, V. monoicum and V. orientale and stem extracts of D. falcata, D. falcata var pubescens, V. articulatum and V.orientale using three different solvents viz., methanol, n-hexane and ethyl acetate. The antifungal activity was tested on three fungal strains include Fusarium oxysporum, Phytophthora infestans, Sclerotium rolfsii. Overall leaf extracts exerted better inhibitory activity than stem counterparts. Among all, only V. orientale was effective against the three fungal species.Compared to stem extracts, leaf extracts of D. falcata var pubescens have shown higher antifungal activity.

scholarly journals Inhibition of Iron Corrosion in Seawater Using Rosemary Extracts (Rosmarinusofficinalis L.)

2019 ◽  
Keyword(s):  
Corrosion Rate ◽  
Environmental Protection ◽  
Organic Compounds ◽  
Inhibitory Activity ◽  
Plant Material ◽  
Corrosion Inhibitors ◽  
High Toxicity ◽  
Iron Corrosion ◽  
Leaf Extracts ◽  
Seawater Corrosion

Due to a growing awareness of environmental protection, an interest in replacing toxic corrosion inhibitors with more environmentally acceptable alternatives is also growing. Chromates, as one of the best inhibitors, have been eliminated as technically viable inhibitors because of their high toxicity, and the use of polyphosphates has diminished as they disrupt the balance in the Plantae kingdom. The emphasis is on exploration and testing of organic compounds that can be obtained from plant material. Rosemary extracts (leaf and flower) have been shown to have inhibitory activity on iron corrosion in 3% NaCl and seawater. Corrosion rate values ​​show that rosemary flower extracts are better inhibitors of corrosion than the leaf extracts and that the maximum inhibitory protection has not been achieved in the range of tested concentrations.

Anti-gout arthritic activities of Ethanolic and Aqueous leaf extracts of Cadaba fruticosa- An In vitro and In silico studies

2021 ◽  
pp. 2587-2592
Author(s):  
Karthikeyan Sekar ◽  
Rajeswary Hari ◽  
P. Ramya ◽  
N. Pusphavalli ◽  
R. Savitha
Keyword(s):  
Matrix Metalloproteinase ◽  
Xanthine Oxidase ◽  
Inhibitory Activity ◽  
In Silico ◽  
Protein Denaturation ◽  
Gouty Arthritis ◽  
Joint Destruction ◽  
Leaf Extracts ◽  
In Silico Studies

In the present investigation an attempt was made to evaluate the in vitro and in silico anti-gout arthritic activity of ethanolic (EECF) and aqueous extracts (AECF) of leaves of Cadaba fruticosa. The in vitro anti-gout arthritic activity of EECF and AECF was evaluated in terms of their inhibitory potential of xanthine oxidase, proteinase enzymes as well as protein denaturation and membrane stabilization using standard protocols. For the analysis of in silico anti-gout arthritic activity, molecular docking was performed for the GC–Ms derived 15 phyto constituents using patch dock server to find a suitable antagonistic ligand for the enzymes cyclooxygenase I and matrix metalloproteinase IV since they are the key enzymes responsible for pain and degenerative changes. Among the EECF and AECF extracts the EECF extract exhibited higher inhibitory activity of the xanthine oxidase and proteinase enzyme. At the concentrations of 800 and 1000μg/ml the observed inhibitory activity was almost similar to the positive drug Allopurinol and Acetyl salicylic acid. Based on the docking score and activation energy the two phyto constituents Quercetin and Cadabicinediacetate inhibited the enzymes cyclooxygenase I and matrix metalloproteinase IV and serves as a better antagonistic ligand to suppress the pain and joint destruction. It may be concluded that the leaves of Cadaba fruticosa may further developed into a effective drug for the management of gouty arthritis due to its multi targeted inhibitory activity of several inflammatory mediators.

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