scholarly journals A highly active worm-like PtMo nanowire for the selective synthesis of dibenzylamines

RSC Advances ◽  
2018 ◽  
Vol 8 (16) ◽  
pp. 8755-8760 ◽  
Author(s):  
Shuanglong Lu ◽  
Pengyao Xu ◽  
Xueqin Cao ◽  
Hongwei Gu
Keyword(s):  
Reductive Amination ◽  
Selective Synthesis ◽  
Synthetic Pathway ◽  
Highly Active

An efficient synthetic pathway of dibenzylamine (DBA) motifs from reductive amination of either aldehydes or nitriles catalyzed by highly active worm-like PtMo nanowires.

Bringing Biocatalysis into the Deuteration Toolbox

2019 ◽  
Author(s):  
Jack Rowbotham ◽  
Oliver Lenz ◽  
Holly Reeve ◽  
Kylie Vincent
Keyword(s):  
Late Stage ◽  
Hydrogen Isotope ◽  
Reductive Amination ◽  
Mechanistic Studies ◽  
Ambient Conditions ◽  
Synthetic Pathway ◽  
Drug Candidates ◽  
Isotopic Selectivity ◽  
Reducing Equivalents

<p></p><p>Chemicals labelled with the heavy hydrogen isotope deuterium (<sup>2</sup>H) have long been used in chemical and biochemical mechanistic studies, spectroscopy, and as analytical tracers. More recently, demonstration of selectively deuterated drug candidates that exhibit advantageous pharmacological traits has spurred innovations in metal-catalysed <sup>2</sup>H insertion at targeted sites, but asymmetric deuteration remains a key challenge. Here we demonstrate an easy-to-implement biocatalytic deuteration strategy, achieving high chemo-, enantio- and isotopic selectivity, requiring only <sup>2</sup>H<sub>2</sub>O (D<sub>2</sub>O) and unlabelled dihydrogen under ambient conditions. The vast library of enzymes established for NADH-dependent C=O, C=C, and C=N bond reductions have yet to appear in the toolbox of commonly employed <sup>2</sup>H-labelling techniques due to requirements for suitable deuterated reducing equivalents. By facilitating transfer of deuterium atoms from <sup>2</sup>H<sub>2</sub>O solvent to NAD<sup>+</sup>, with H<sub>2</sub> gas as a clean reductant, we open up biocatalysis for asymmetric reductive deuteration as part of a synthetic pathway or in late stage functionalisation. We demonstrate enantioselective deuteration via ketone and alkene reductions and reductive amination, as well as exquisite chemo-control for deuteration of compounds with multiple unsaturated sites.</p><p></p>

Selective Synthesis of Primary Amines by Reductive Amination of Ketones with Ammonia over Supported Pt catalysts

ChemCatChem ◽  
2015 ◽  
Vol 7 (6) ◽  
pp. 921-924 ◽  
Author(s):  
Yoichi Nakamura ◽  
Kenichi Kon ◽  
Abeda Sultana Touchy ◽  
Ken-ichi Shimizu ◽  
Wataru Ueda
Keyword(s):  
Reductive Amination ◽  
Primary Amines ◽  
Selective Synthesis ◽  
Pt Catalysts ◽  
Supported Pt Catalysts

Ethylenediamine-functionalized magnetic Fe3O4@SiO2 nanoparticles: cooperative trifunctional catalysis for selective synthesis of nitroalkenes

RSC Advances ◽  
2015 ◽  
Vol 5 (90) ◽  
pp. 73684-73691 ◽  
Author(s):  
Fengjun Xue ◽  
Yahao Dong ◽  
Peibo Hu ◽  
Yanan Deng ◽  
Yuping Wei
Keyword(s):  
Secondary Amine ◽  
Primary Amine ◽  
Sio2 Nanoparticles ◽  
Selective Synthesis ◽  
Oh Groups ◽  
Highly Active ◽  
Magnetic Fe3o4

The designed nanocatalyst Fe3O4@SiO2–NH2 was highly active for selective synthesis of nitroalkenes through cooperative trifunctional catalysis of primary amine, secondary amine and Si–OH groups.

scholarly journals Preparation of Highly Active Monometallic Rhenium Catalysts for Selective Synthesis of 1,4‐Butanediol from 1,4‐Anhydroerythritol

ChemSusChem ◽  
2019 ◽  
Vol 12 (15) ◽  
pp. 3615-3626 ◽  
Author(s):  
Tianmiao Wang ◽  
Masazumi Tamura ◽  
Yoshinao Nakagawa ◽  
Keiichi Tomishige
Keyword(s):  
Selective Synthesis ◽  
Highly Active

ChemInform Abstract: Highly Active Phosphine-Free Bifunctional Iron Complex for Hydrogenation of Bicarbonate and Reductive Amination.

ChemInform ◽  
2015 ◽  
Vol 46 (37) ◽  
pp. no-no
Author(s):  
Trieu-Tien Thai ◽  
Delphine S. Merel ◽  
Albert Poater ◽  
Sylvain Gaillard ◽  
Jean-Luc Renaud
Keyword(s):  
Reductive Amination ◽  
Iron Complex ◽  
Highly Active

ChemInform Abstract: Highly Active and Selective Synthesis of Imines from Alcohols and Amines or Nitroarenes Catalyzed by Pd/DNA in Water with Dehydrogenation.

ChemInform ◽  
2013 ◽  
Vol 44 (15) ◽  
pp. no-no
Author(s):  
Lin Tang ◽  
Huayin Sun ◽  
Yunfeng Li ◽  
Zhenggen Zha ◽  
Zhiyong Wang
Keyword(s):  
Selective Synthesis ◽  
Highly Active

Spatially and Size Selective Synthesis of Fe-Based Nanoparticles on Ordered Mesoporous Supports as Highly Active and Stable Catalysts for Ammonia Decomposition

2010 ◽  
Vol 132 (40) ◽  
pp. 14152-14162 ◽  
Author(s):  
An-Hui Lu ◽  
Joerg-Joachim Nitz ◽  
Massimiliano Comotti ◽  
Claudia Weidenthaler ◽  
Klaus Schlichte ◽  
...  
Keyword(s):  
Ammonia Decomposition ◽  
Selective Synthesis ◽  
Highly Active ◽  
Ordered Mesoporous ◽  
Mesoporous Supports

Reusable Nickel Nanoparticles‐Catalyzed Reductive Amination for Selective Synthesis of Primary Amines

2019 ◽  
Vol 58 (15) ◽  
pp. 5064-5068 ◽  
Author(s):  
Kathiravan Murugesan ◽  
Matthias Beller ◽  
Rajenahally V. Jagadeesh
Keyword(s):  
Reductive Amination ◽  
Nickel Nanoparticles ◽  
Primary Amines ◽  
Selective Synthesis

scholarly journals Chemicals from Biomass: Selective Synthesis of N-Substituted Furfuryl Amines by the One-Pot Direct Reductive Amination of Furanic Aldehydes

2019 ◽  
Vol 7 (6) ◽  
pp. 6243-6250 ◽  
Author(s):  
Andrea García-Ortiz ◽  
Juan D. Vidal ◽  
Maria J. Climent ◽  
Patricia Concepción ◽  
Avelino Corma ◽  
...  
Keyword(s):  
Reductive Amination ◽  
Selective Synthesis ◽  
One Pot ◽  
The One
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