Reusable Nickel Nanoparticles‐Catalyzed Reductive Amination for Selective Synthesis of Primary Amines

2019 ◽  
Vol 58 (15) ◽  
pp. 5064-5068 ◽  
Author(s):  
Kathiravan Murugesan ◽  
Matthias Beller ◽  
Rajenahally V. Jagadeesh
Keyword(s):  
Reductive Amination ◽  
Nickel Nanoparticles ◽  
Primary Amines ◽  
Selective Synthesis

Reusable Nickel Nanoparticles‐Catalyzed Reductive Amination for Selective Synthesis of Primary Amines

2019 ◽  
Vol 131 (15) ◽  
pp. 5118-5122 ◽  
Author(s):  
Kathiravan Murugesan ◽  
Matthias Beller ◽  
Rajenahally V. Jagadeesh
Keyword(s):  
Reductive Amination ◽  
Nickel Nanoparticles ◽  
Primary Amines ◽  
Selective Synthesis

Selective Synthesis of Primary Amines by Reductive Amination of Ketones with Ammonia over Supported Pt catalysts

ChemCatChem ◽  
2015 ◽  
Vol 7 (6) ◽  
pp. 921-924 ◽  
Author(s):  
Yoichi Nakamura ◽  
Kenichi Kon ◽  
Abeda Sultana Touchy ◽  
Ken-ichi Shimizu ◽  
Wataru Ueda
Keyword(s):  
Reductive Amination ◽  
Primary Amines ◽  
Selective Synthesis ◽  
Pt Catalysts ◽  
Supported Pt Catalysts

scholarly journals General and selective synthesis of primary amines using Ni-based homogeneous catalysts

2020 ◽  
Vol 11 (17) ◽  
pp. 4332-4339 ◽  
Author(s):  
Kathiravan Murugesan ◽  
Zhihong Wei ◽  
Vishwas G. Chandrashekhar ◽  
Haijun Jiao ◽  
Matthias Beller ◽  
...  
Keyword(s):  
Carbonyl Compounds ◽  
Reductive Amination ◽  
Primary Amines ◽  
Homogeneous Catalyst ◽  
Selective Synthesis ◽  
Homogeneous Catalysts

A Ni-triphos based homogeneous catalyst enabled the synthesis of all kinds of primary amines by reductive amination of carbonyl compounds with ammonia and hydrogenation of nitroarenes.

ChemInform Abstract: Selective Synthesis of Primary Amines by Reductive Amination of Ketones with Ammonia over Supported Pt Catalysts.

ChemInform ◽  
2015 ◽  
Vol 46 (32) ◽  
pp. no-no
Author(s):  
Yoichi Nakamura ◽  
Kenichi Kon ◽  
Abeda Sultana Touchy ◽  
Ken-ichi Shimizu ◽  
Wataru Ueda
Keyword(s):  
Reductive Amination ◽  
Primary Amines ◽  
Selective Synthesis ◽  
Pt Catalysts ◽  
Supported Pt Catalysts

Self-regulated catalysis for selective synthesis of primary amines from carbonyl compounds

2021 ◽  
Author(s):  
Mingxia Gao ◽  
Xiuquan Jia ◽  
Jiping Ma ◽  
Xiaomeng Fan ◽  
Jin Gao ◽  
...  
Keyword(s):  
Carbonyl Compounds ◽  
Reductive Amination ◽  
Primary Amines ◽  
Selective Synthesis ◽  
General Synthesis

Most current processes for the general synthesis of primary amines by reductive amination are performed with enormously excessive amounts of hazardous ammonia. It remains unclear how catalysts should be designed...

Primary Amines by Transfer Hydrogenative Reductive Amination of Ketones by Using Cyclometalated IrIIICatalysts

2013 ◽  
Vol 20 (1) ◽  
pp. 245-252 ◽  
Author(s):  
Dinesh Talwar ◽  
Noemí Poyatos Salguero ◽  
Craig M. Robertson ◽  
Jianliang Xiao
Keyword(s):  
Reductive Amination ◽  
Primary Amines

Ambient-Temperature Synthesis of Primary Amines via Reductive Amination of Carbonyl Compounds

ACS Catalysis ◽  
2020 ◽  
Vol 10 (14) ◽  
pp. 7763-7772 ◽  
Author(s):  
Chao Xie ◽  
Jinliang Song ◽  
Manli Hua ◽  
Yue Hu ◽  
Xin Huang ◽  
...  
Keyword(s):  
Ambient Temperature ◽  
Carbonyl Compounds ◽  
Reductive Amination ◽  
Primary Amines ◽  
Temperature Synthesis

scholarly journals 2,3-Diaminopropanols Obtained from d-Serine as Intermediates in the Synthesis of Protected 2,3-l-Diaminopropanoic Acid (l-Dap) Methyl Esters

Molecules ◽  
2020 ◽  
Vol 25 (6) ◽  
pp. 1313
Author(s):  
Andrea Temperini ◽  
Donatella Aiello ◽  
Fabio Mazzotti ◽  
Constantinos M. Athanassopoulos ◽  
Pierantonio De Luca ◽  
...  
Keyword(s):  
Amino Acid ◽  
Reductive Amination ◽  
Methyl Esters ◽  
Primary Amines ◽  
Synthetic Approach ◽  
Protecting Group ◽  
Synthetic Strategy ◽  
Crude Product ◽  
Diaminopropanoic Acid ◽  
Acid Labile

A synthetic strategy for the preparation of two orthogonally protected methyl esters of the non-proteinogenic amino acid 2,3-l-diaminopropanoic acid (l-Dap) was developed. In these structures, the base-labile protecting group 9-fluorenylmethyloxycarbonyl (Fmoc) was paired to the p-toluensulfonyl (tosyl, Ts) or acid-labile tert-butyloxycarbonyl (Boc) moieties. The synthetic approach to protected l-Dap methyl esters uses appropriately masked 2,3-diaminopropanols, which are obtained via reductive amination of an aldehyde prepared from the commercial amino acid Nα-Fmoc-O-tert-butyl-d-serine, used as the starting material. Reductive amination is carried out with primary amines and sulfonamides, and the process is assisted by the Lewis acid Ti(OiPr)4. The required carboxyl group is installed by oxidizing the alcoholic function of 2,3-diaminopropanols bearing the tosyl or benzyl protecting group on the 3-NH2 site. The procedure can easily be applied using the crude product obtained after each step, minimizing the need for chromatographic purifications. Chirality of the carbon atom of the starting d-serine template is preserved throughout all synthetic steps.

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