Rapid conjugation of nanoparticles, proteins and siRNAs to microbubbles by strain-promoted click chemistry for ultrasound imaging and drug delivery

2019 ◽  
Vol 10 (6) ◽  
pp. 705-717 ◽  
Author(s):  
Xifeng Liu ◽  
Ping Gong ◽  
Pengfei Song ◽  
Feng Xie ◽  
A. Lee Miller II ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Click Chemistry ◽  
Ultrasound Imaging ◽  
Ultrasound Microbubbles

Strain-promoted alkyne–azide cycloaddition (SPAAC) click chemistry was applied for the rapid conjugation of nanoparticles, proteins, and siRNA-micelles to ultrasound microbubbles.

pH-Triggered release of gemcitabine from polymer coated nanodiamonds fabricated by RAFT polymerization and copper free click chemistry

2016 ◽  
Vol 7 (40) ◽  
pp. 6220-6230 ◽  
Author(s):  
Haiwang Lai ◽  
Mingxia Lu ◽  
Hongxu Lu ◽  
Martina H. Stenzel ◽  
Pu Xiao
Keyword(s):  
Drug Delivery ◽  
Pancreatic Cancer ◽  
Click Chemistry ◽  
Raft Polymerization ◽  
Stimuli Responsive ◽  
Triggered Release

Prodrug (gemcitabine)-based polymer coated nanodiamonds as stimuli-responsive drug delivery platforms for the treatment of pancreatic cancer.

scholarly journals Motion Compensated Ultrasound Imaging Allows Thermometry and Image Guided Drug Delivery Monitoring from Echogenic Liposomes

Theranostics ◽  
2016 ◽  
Vol 6 (11) ◽  
pp. 1963-1974 ◽  
Author(s):  
Kalyani Ektate ◽  
Ankur Kapoor ◽  
Danny Maples ◽  
Ahmet Tuysuzoglu ◽  
Joshua VanOsdol ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Ultrasound Imaging ◽  
Image Guided ◽  
Echogenic Liposomes ◽  
Image Guided Drug Delivery

scholarly journals Synthesis of thiolated and acrylated nanoparticles using thiol-ene click chemistry: towards novel mucoadhesive materials for drug delivery

RSC Advances ◽  
2013 ◽  
Vol 3 (30) ◽  
pp. 12275 ◽  
Author(s):  
Anna Štorha ◽  
Ellina A. Mun ◽  
Vitaliy V. Khutoryanskiy
Keyword(s):  
Drug Delivery ◽  
Click Chemistry

scholarly journals Ultrasound Microbubbles Enhance the Neuroprotective Effect of Mouse Nerve Growth Factor on Intraocular Hypertension-Induced Neuroretina Damage in Rabbits

2016 ◽  
Vol 2016 ◽  
pp. 1-9
Author(s):  
Xiaoli Shen ◽  
Lina Huang ◽  
Dahui Ma ◽  
Jun Zhao ◽  
Yi Xie ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Blood Circulation ◽  
Neuroprotective Effect ◽  
Whole Body ◽  
Destruction Process ◽  
Optic Nerve Damage ◽  
Neuroprotective Drugs ◽  
Target Organs ◽  
Whole Body Metabolism ◽  
Ultrasound Microbubbles

Ultrasound microbubble combined optic protection drugs have obvious protective effect on optic nerve damage. This way of targeting drug delivery is becoming more simple, not through the whole body metabolism, avoiding drug via blood circulation when facing the decomposition and the environment in the interference and destruction process of drugs, to maximize the guarantee to reach target organs of drug concentration and to reache the maximum therapeutic effect. The technique of ultrasound microbubbles is safe, controllable, nonimmunogenic, and repeatable. It provides us with a novel idea in the administration of neuroprotective drugs.

Nanoparticle-Coated Microbubbles for Combined Ultrasound Imaging and Drug Delivery

Langmuir ◽  
2019 ◽  
Vol 35 (31) ◽  
pp. 10087-10096 ◽  
Author(s):  
Akaki Jamburidze ◽  
Axel Huerre ◽  
Diego Baresch ◽  
Vincent Poulichet ◽  
Marco De Corato ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Ultrasound Imaging

Preparation of pH-responsive hollow poly(MAA-co-EGDMA) nanocapsules for drug delivery and ultrasound imaging

RSC Advances ◽  
2016 ◽  
Vol 6 (105) ◽  
pp. 103754-103762 ◽  
Author(s):  
He Hu ◽  
Xiaofen Zhang ◽  
Jin Sun ◽  
Lu An ◽  
Jing Du ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Ultrasound Imaging ◽  
Ph Responsive

The biocompatible hollow poly(MAA-co-EGDMA) nanocapsules with size of 260 nm shown controlled DOX drug delivery and effective ultrasound imaging.

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