Compartmentalized nanoparticles in aqueous solution through hierarchical self-assembly of triblock glycopolymers

2018 ◽  
Vol 9 (30) ◽  
pp. 4132-4142 ◽  
Author(s):  
Alberto Piloni ◽  
Andreas Walther ◽  
Martina H. Stenzel
Keyword(s):  
Aqueous Solution ◽  
Block Copolymers ◽  
Self Assembly ◽  
Biomedical Applications ◽  
Functional Materials ◽  
Drug Carriers ◽  
Amphiphilic Block Copolymers

Amphiphilic block copolymers can elegantly assemble in water to form well-defined nano-objects and through smart design of the polymers it is possible to efficiently prepare functional materials for biomedical applications such as drug carriers.

scholarly journals Glucose-bearing biodegradable poly(amino acid) and poly(amino acid)-poly(ester) conjugates for controlled payload release

2016 ◽  
Vol 4 (12) ◽  
pp. 1792-1801 ◽  
Author(s):  
Mthulisi Khuphe ◽  
Clare S. Mahon ◽  
Paul D. Thornton
Keyword(s):  
Aqueous Solution ◽  
Amino Acid ◽  
Block Copolymers ◽  
Self Assembly ◽  
Ring Opening ◽  
Amphiphilic Block Copolymers ◽  
Biodegradable Poly

The glucoseamine-initiated ring-opening polymerisation of amino acid N-carboxyanhydrides and O-carboxanhydrides to yield amphiphilic block copolymers that are capable of self-assembly in aqueous solution to form well-defined, glucose-presenting, particles is reported.

scholarly journals Polymerisation-induced self-assembly (PISA) as a straightforward formulation strategy for stimuli-responsive drug delivery systems and biomaterials: recent advances

2021 ◽  
Vol 9 (1) ◽  
pp. 38-50
Author(s):  
Hien Phan ◽  
Vincenzo Taresco ◽  
Jacques Penelle ◽  
Benoit Couturaud
Keyword(s):  
Drug Delivery ◽  
Block Copolymers ◽  
Drug Release ◽  
Self Assembly ◽  
Drug Delivery Systems ◽  
Amphiphilic Block Copolymers ◽  
Stimuli Responsive ◽  
Site Specific ◽  
On Demand ◽  
Redox Agents

Stimuli-responsive amphiphilic block copolymers obtained by PISA have emerged as promising nanocarriers for enhancing site-specific and on-demand drug release in response to a range of stimuli such as pH, redox agents, light or temperature.

Small molecule-mediated self-assembly behaviors of Pluronic block copolymers in aqueous solution: impact of hydrogen bonding on the morphological transition of Pluronic micelles

Soft Matter ◽  
2020 ◽  
Vol 16 (1) ◽  
pp. 142-151 ◽  
Author(s):  
Haiyan Luo ◽  
Kun Jiang ◽  
Xiangfeng Liang ◽  
Huizhou Liu ◽  
Yingbo Li
Keyword(s):  
Aqueous Solution ◽  
Hydrogen Bonding ◽  
Block Copolymers ◽  
Small Molecules ◽  
Small Molecule ◽  
Propyl Gallate ◽  
Self Assembly ◽  
Morphological Transition ◽  
Propyl Paraben ◽  
Pluronic P123

The influence of hydrogen bonding on the morphological transition of Pluronic P123 micelles is experimentally and theoretically investigated by introducing three small molecules, i.e. propyl benzoate (PB), propyl paraben (PP) and propyl gallate (PG).

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