The synthesis of benzimidazoles via a recycled palladium catalysed hydrogen transfer under mild conditions

2018 ◽  
Vol 16 (12) ◽  
pp. 2088-2096 ◽  
Author(s):  
Qianqian Guan ◽  
Qi Sun ◽  
Lixian Wen ◽  
Zhenggen Zha ◽  
Yu Yang ◽  
...  
Keyword(s):  
Hydrogen Transfer ◽  
Efficient Synthesis ◽  
Mild Conditions ◽  
Palladium Catalyzed

An efficient synthesis of benzimidazoles was developed by virtue of a recycled palladium catalyzed hydrogen transfer.

scholarly journals Palladium-Catalyzed Cross-Coupling of Gem-Bromofluoroalkenes with Alkylboronic Acids for the Synthesis of Alkylated Monofluoroalkenes

Molecules ◽  
2020 ◽  
Vol 25 (23) ◽  
pp. 5532
Author(s):  
Laëtitia Chausset-Boissarie ◽  
Nicolas Cheval ◽  
Christian Rolando
Keyword(s):  
Organic Synthesis ◽  
Functional Group ◽  
Materials Science ◽  
Cross Coupling ◽  
High Yield ◽  
Efficient Synthesis ◽  
Mild Conditions ◽  
Wide Range ◽  
Palladium Catalyzed ◽  
Novel Strategy

Monofluoroalkenes are versatile fluorinated synthons in organic synthesis, medicinal chemistry and materials science. In light of the importance of alkyl-substituted monofluoroalkenes efficient synthesis of these moieties still represents a synthetic challenge. Herein, we described a mild and efficient methodology to obtain monofluoroalkenes through a stereospecific palladium-catalyzed alkylation of gem-bromofluoroalkenes with primary and strained secondary alkylboronic acids under mild conditions. This novel strategy gives access to a wide range of functionalized tri- and tetrasubstituted monofluoroalkenes in high yield, with good functional group tolerance, independently from the gem-bromofluoroalkenes geometry.

An efficient transformation of primary halides into nitriles through palladium-catalyzed hydrogen transfer reaction

2015 ◽  
Vol 51 (53) ◽  
pp. 10714-10717 ◽  
Author(s):  
Tao Zou ◽  
Xiaoqiang Yu ◽  
Xiujuan Feng ◽  
Ming Bao
Keyword(s):  
Hydrogen Transfer ◽  
Transfer Reaction ◽  
Hydrogen Acceptor ◽  
One Pot ◽  
Mild Conditions ◽  
Hydrogen Transfer Reaction ◽  
Efficient Transformation ◽  
Palladium Catalyzed

Two-step one-pot transformation of primary halides into the corresponding nitriles is successfully achieved under mild conditions. In this protocol, acetone functions as both a solvent and a hydrogen acceptor.

Palladium-catalyzed N-arylsulfonamide formation from arylsulfonyl hydrazides and nitroarenes

RSC Advances ◽  
2016 ◽  
Vol 6 (16) ◽  
pp. 13010-13013 ◽  
Author(s):  
Feng Zhao ◽  
Bin Li ◽  
Huawen Huang ◽  
Guo-Jun Deng
Keyword(s):  
Hydrogen Transfer ◽  
Palladium Catalyzed

Various N-arylsulfonamides were prepared from nitroarenes and arylsulfonyl hydrazides via hydrogen transfer methodology.

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