Flap endonuclease-initiated enzymatic repairing amplification for ultrasensitive detection of target nucleic acids

Nanoscale ◽  
2019 ◽  
Vol 11 (8) ◽  
pp. 3633-3638 ◽  
Author(s):  
Hyowon Jang ◽  
Chang Yeol Lee ◽  
Seoyoung Lee ◽  
Ki Soo Park ◽  
Hyun Gyu Park
Keyword(s):  
Nucleic Acid ◽  
Nucleic Acids ◽  
Nucleic Acid Amplification ◽  
Ultrasensitive Detection ◽  
Isothermal Nucleic Acid Amplification ◽  
Amplification Method

A new isothermal nucleic acid amplification method termed FERA (Flap endonuclease-initiated Enzymatic Repairing Amplification) is developed for the ultrasensitive detection of target nucleic acids.

A novel exonuclease-assisted isothermal nucleic acid amplification with ultrahigh specificity mediated by full-length Bst DNA polymerase

2018 ◽  
Vol 54 (75) ◽  
pp. 10562-10565 ◽  
Author(s):  
Xin Ye ◽  
Yang Li ◽  
Lijuan Wang ◽  
Xueen Fang ◽  
Jilie Kong
Keyword(s):  
Nucleic Acid ◽  
Nucleic Acids ◽  
Dna Polymerase ◽  
Isothermal Amplification ◽  
Full Length ◽  
Nucleic Acid Amplification ◽  
Isothermal Nucleic Acid Amplification

A novel exonuclease-assisted isothermal amplification to amplify and determine nucleic acids very sensitively and with ultrahigh specificity.

scholarly journals Polymerase Spiral Reaction (PSR): A novel isothermal nucleic acid amplification method

2015 ◽  
Vol 5 (1) ◽  
Author(s):  
Wei Liu ◽  
Derong Dong ◽  
Zhan Yang ◽  
Dayang Zou ◽  
Zeliang Chen ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Nucleic Acid Amplification ◽  
Isothermal Nucleic Acid Amplification ◽  
Amplification Method

Liquid biopsy in combination with solid-state electrochemical sensors and nucleic acid amplification

2019 ◽  
Vol 7 (43) ◽  
pp. 6655-6669 ◽  
Author(s):  
Miyuki Tabata ◽  
Yuji Miyahara
Keyword(s):  
Solid State ◽  
Nucleic Acid ◽  
Nucleic Acids ◽  
Liquid Biopsy ◽  
Electrochemical Sensors ◽  
Nucleic Acid Amplification ◽  
Isothermal Nucleic Acid Amplification

Solid-state electrochemical sensors are developing as a new platform for liquid biopsy, combining detection and analysis of nucleic acids with isothermal nucleic acid amplification reactions.

Ultrasensitive detection of microRNAs using catalytic hairpin assembly coupled with enzymatic repairing amplification

2016 ◽  
Vol 52 (93) ◽  
pp. 13584-13587 ◽  
Author(s):  
Chong-Hua Zhang ◽  
Ying Tang ◽  
Ying-Ying Sheng ◽  
Hui Wang ◽  
Zhan Wu ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Nucleic Acid Amplification ◽  
Ultrasensitive Detection ◽  
Isothermal Nucleic Acid Amplification ◽  
Nucleic Acid Amplification Technology ◽  
Catalytic Hairpin Assembly ◽  
Mirna Detection

A novel isothermal nucleic acid amplification technology is developed by coupling CHA with enzymatic repairing amplification for sensitive and selective miRNA detection.

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