Polymerization-like kinetics of the self-assembly of colloidal nanoparticles into supracolloidal polymers

Nanoscale ◽  
2018 ◽  
Vol 10 (35) ◽  
pp. 16873-16880 ◽  
Author(s):  
Xiaodong Ma ◽  
Yaru Zhou ◽  
Liangshun Zhang ◽  
Jiaping Lin ◽  
Xiaohui Tian
Keyword(s):  
Self Assembly ◽  
Rate Coefficient ◽  
Polymerization Kinetics ◽  
Colloidal Nanoparticles ◽  
Variable Rate ◽  
Molecular Systems ◽  
Diffusion Controlled ◽  
Step Growth ◽  
Step Growth Polymerization ◽  
Kinetics Of

Unlike the polymerization kinetics of molecular systems, the growth of supracolloidal polymers obeys diffusion-controlled step-growth polymerization kinetics with a variable rate coefficient.

Supramolecular step-growth polymerization kinetics of pre-assembled triblock copolymer micelles

2019 ◽  
Vol 10 (25) ◽  
pp. 3461-3468 ◽  
Author(s):  
Yingqing Lu ◽  
Liang Gao ◽  
Jiaping Lin ◽  
Liquan Wang ◽  
Liangshun Zhang ◽  
...  
Keyword(s):  
Triblock Copolymer ◽  
Polymerization Kinetics ◽  
Structural Defects ◽  
Step Growth ◽  
Step Growth Polymerization ◽  
Copolymer Micelles ◽  
Kinetics Of

Pre-assembled copolymer micelles were found to “polymerize” into hierarchical nanowires, induced by the structural defects on the micelle surfaces.

scholarly journals Synthesis and Polymerization Kinetics of Rigid Tricyanate Ester

Polymers ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 1686
Author(s):  
Andrey Galukhin ◽  
Roman Nosov ◽  
Ilya Nikolaev ◽  
Elena Melnikova ◽  
Daut Islamov ◽  
...  
Keyword(s):  
Kinetic Analysis ◽  
Single Step ◽  
Polymerization Kinetics ◽  
Scanning Calorimetry ◽  
Modulated Differential Scanning Calorimetry ◽  
Diffusion Controlled ◽  
Polymerization Product ◽  
The One ◽  
Kinetics Of

A new rigid tricyanate ester consisting of seven conjugated aromatic units is synthesized, and its structure is confirmed by X-ray analysis. This ester undergoes thermally stimulated polymerization in a liquid state. Conventional and temperature-modulated differential scanning calorimetry techniques are employed to study the polymerization kinetics. A transition of polymerization from a kinetic- to a diffusion-controlled regime is detected. Kinetic analysis is performed by combining isoconversional and model-based computations. It demonstrates that polymerization in the kinetically controlled regime of the present monomer can be described as a quasi-single-step, auto-catalytic, process. The diffusion contribution is parameterized by the Fournier model. Kinetic analysis is complemented by characterization of thermal properties of the corresponding polymerization product by means of thermogravimetric and thermomechanical analyses. Overall, the obtained experimental results are consistent with our hypothesis about the relation between the rigidity and functionality of the cyanate ester monomer, on the one hand, and its reactivity and glass transition temperature of the corresponding polymer, on the other hand.

Direct insight into the kinetics of the high-pressure step-growth polymerization of DGEBA/aniline model system

Polymer ◽  
2019 ◽  
Vol 172 ◽  
pp. 322-329 ◽  
Author(s):  
Andrzej Dzienia ◽  
Kajetan Koperwas ◽  
Magdalena Tarnacka ◽  
Mirosław Chorążewski ◽  
Eugene B. Postnikov ◽  
...  
Keyword(s):  
High Pressure ◽  
Model System ◽  
Pressure Step ◽  
Step Growth ◽  
Step Growth Polymerization ◽  
Kinetics Of ◽  
Insight Into

Network Formation Kinetics of Poly(dimethylsiloxane) Based on Step-Growth Polymerization

2021 ◽  
Vol 54 (17) ◽  
pp. 7678-7689 ◽  
Author(s):  
Jie Jin ◽  
Ru-Qiu Zheng ◽  
Yin-Ning Zhou ◽  
Zheng-Hong Luo
Keyword(s):  
Network Formation ◽  
Formation Kinetics ◽  
Step Growth ◽  
Step Growth Polymerization ◽  
Kinetics Of

scholarly journals Supramolecular self-assembly of a polyelectrolyte chain based on step-growth polymerization of hydrophobic and hydrophilic monomers

RSC Advances ◽  
2017 ◽  
Vol 7 (83) ◽  
pp. 52832-52840
Author(s):  
Li Sun ◽  
Shang Ma ◽  
Chen Wang ◽  
Yongmei Chi ◽  
Jian Dong
Keyword(s):  
Citric Acid ◽  
Self Assembly ◽  
The Self ◽  
Hexamethylene Diisocyanate ◽  
Cross Linking ◽  
Polyelectrolyte Chain ◽  
Step Growth ◽  
Step Growth Polymerization ◽  
Hydrophilic Monomers

Polymerization of citric acid and hexamethylene diisocyanate and hydrolysis results in a polyelectrolyte PHMC. Noncovalent cross-linking of cooperative H-bonding units stabilizes the self-assembly of the PHMC chains into nanoparticles in water.

scholarly journals Engineering of Doxorubicin-Encapsulating and TRAIL-Conjugated Poly(RGD) Proteinoid Nanocapsules for Drug Delivery Applications

Polymers ◽  
2020 ◽  
Vol 12 (12) ◽  
pp. 2996
Author(s):  
Elad Hadad ◽  
Safra Rudnick-Glick ◽  
Ella Itzhaki ◽  
Matan Y. Avivi ◽  
Igor Grinberg ◽  
...  
Keyword(s):  
Side Effects ◽  
Self Assembly ◽  
Tumor Therapy ◽  
Ovarian Cancer Cells ◽  
Chemotherapeutic Drug ◽  
Enzyme Degradation ◽  
Wide Range ◽  
Step Growth ◽  
Step Growth Polymerization ◽  
Necrosis Factor

Proteinoids are non-toxic biodegradable polymers prepared by thermal step-growth polymerization of amino acids. Here, P(RGD) proteinoids and proteinoid nanocapsules (NCs) based on D-arginine, glycine, and L-aspartic acid were synthesized and characterized for targeted tumor therapy. Doxorubicin (Dox), a chemotherapeutic drug used for treatment of a wide range of cancers, known for its adverse side effects, was encapsulated during self-assembly to form Dox/P(RGD) NCs. In addition, tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), which can initiate apoptosis in most tumor cells but undergoes fast enzyme degradation, was stabilized by covalent conjugation to hollow P(RGD) NCs. The effect of polyethylene glycol (PEG) conjugation was also studied. Cytotoxicity tests on CAOV-3 ovarian cancer cells demonstrated that Dox/P(RGD) and TRAIL-P(RGD) NCs were as effective as free Dox and TRAIL with cell viability of 2% and 10%, respectively, while PEGylated NCs were less effective. Drug-bearing P(RGD) NCs offer controlled release with reduced side effects for improved therapy.

DSC investigations on the kinetics of the linear step growth polymerization of dian-bisglycidylether with amines

1985 ◽  
Vol 92 ◽  
pp. 185-188 ◽  
Author(s):  
H.J. Flammersheim ◽  
H. Hörhold ◽  
K. Bellstedt ◽  
J. Klee
Keyword(s):  
Step Growth ◽  
Step Growth Polymerization ◽  
Kinetics Of

COMPARATIVE STUDY ON THE ADSORPTION PROCESSES OF ALKANETHIOL AND ALKANEDITHIOL ON GOLD

2010 ◽  
Vol 17 (04) ◽  
pp. 397-403 ◽  
Author(s):  
HUI HE ◽  
YAN GUO ◽  
SHOUFU WANG ◽  
YAQING JIANG
Keyword(s):  
Self Assembly ◽  
Surface Coverage ◽  
Self Assembled Monolayers ◽  
Diffusion Controlled ◽  
Assembled Monolayers ◽  
Adsorption Processes ◽  
Kinetics Of Formation ◽  
Initial Adsorption ◽  
Adsorption Rates ◽  
Kinetics Of

The kinetics of formation of self-assembled monolayers on gold generated by the adsorption of 1-octanethiol and 1,8-octanedithiol were explored by electrochemistry measurement. The time dependence of capacitance and surface coverage supported that the adsorption of thiols typically processed with a two-step adsorption consisted of a fast initial adsorption and a slowly following reorganization. From the function of surface coverage versus time, one could get rate constants of adsorption of thiols, and the adsorption process was demonstrated to follow a diffusion-controlled Langmuir model. A comparison of the adsorption rates for different concentration between 1-octanethiol and 1,8-octanedithiol revealed that their adsorption processes were almost identical and independent on the concentration, inferring that only one sulfur atom contributed to the self-assembly of dithiol molecule.

scholarly journals Designed proteinoid polymers and nanoparticles encapsulating risperidone for enhanced antipsychotic activity

2020 ◽  
Vol 18 (1) ◽  
Author(s):  
L. Lugasi ◽  
I. Grinberg ◽  
S. Rudnick-Glick ◽  
E. Okun ◽  
H. Einat ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Self Assembly ◽  
Drug Loading ◽  
Drug Efficacy ◽  
Aqueous Solubility ◽  
Antipsychotic Activity ◽  
Step Growth ◽  
Step Growth Polymerization ◽  
Drug Efficiency ◽  
Atypical Antipsychotic Medication

Abstract Background Nanoparticles (NPs) incorporating drug formulations can be used to facilitate passage through biological barriers including the blood–brain barrier (BBB) and increase drug delivery and bioavailability. Hence, NP-based administration may enhance the efficiency of current antipsychotics. Encapsulation within NPs can resolve aqueous solubility problems that not only reduce permeability through the BBB but also affect targeting. The present study describes a new drug delivery system based on proteinoid NPs to explore the possibility of improving drug efficacy. Risperidone (RSP) is a commonly used atypical antipsychotic medication, and was therefore selected for encapsulation by proteinoid NPs. Results Proteinoid polymers with high molecular weight and low polydispersity were synthesized from l-amino acids and poly-l-lactic acid (PLLA) by thermal step-growth polymerization mechanism. RSP-loaded proteinoid NPs were then prepared using a self-assembly process in the presence of RSP, followed by PEGylation. The optimal PEGylated RSP-loaded NPs were characterized in terms of diameter and size distribution, drug loading, ζ-potential, cytotoxicity, biodistribution, and psychopharmacological effects. The findings indicate significantly higher antipsychotic activity of drug-loaded proteinoid NPs compared to free RSP. Conclusions Proteinoid NPs enhance RSP delivery and may potentially increase drug efficiency by reducing dosage and side effects.

Research on the Reaction of IPDI and PPG with Organo-Tin Mixed Catalyst

2012 ◽  
Vol 430-432 ◽  
pp. 399-403
Author(s):  
Yuan Wei ◽  
Shu Lin An ◽  
Su Ran Liao
Keyword(s):  
Activation Energy ◽  
Molecular Weight ◽  
Order Equation ◽  
Polypropylene Glycol ◽  
Step Process ◽  
Mixed Catalyst ◽  
Step Growth ◽  
Step Growth Polymerization ◽  
Kinetics Of ◽  
Polymerization Conditions

The kinetics of the reaction is essential for the synthesis of polyurethane. In this study, the reaction kinetics and polymerization conditions in two-step process of isophorone diisocyante (IPDI) and polypropylene glycol (PPG) with organo-tin mixed catalyst were investigated by chemical titration. The results showed that the reaction obeyed the second-order equation of step-growth polymerization, the rate constants of IPDI and PPG reaction at 50, 60 and 70°C were 0.0161, 0.0373 and 0.0806 kg•mol-1•min-1，respectively. The activation energy obtained from the result was 74.25 kJ•mol-1. The polyurethane with number molecular weight 38721 was synthesized and was characterized by Fourier transform infrared (FTIR).

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