Development of a two-photon turn-on fluorescent probe for cysteine and its bio-imaging applications in living cells, tissues, and zebrafish

2018 ◽  
Vol 42 (17) ◽  
pp. 14075-14078 ◽  
Author(s):  
Shiying Gao ◽  
Yonghe Tang ◽  
Weiying Lin

A two-photon fluorescent probe Co-Cys for detecting cysteine has been designed to monitor cysteine in cells, tissues and zebrafish.

2015 ◽  
Vol 7 (6) ◽  
pp. 2386-2390 ◽  
Author(s):  
Tun Tang ◽  
Yimin Zhou ◽  
Yuqi Chen ◽  
Mengjun Li ◽  
Yan Feng ◽  
...  

A novel two-photon fluorescent “turn-on” probe could detect methylglyoxal levels in living cells conveniently.


The Analyst ◽  
2019 ◽  
Vol 144 (5) ◽  
pp. 1704-1710 ◽  
Author(s):  
Shan Yao ◽  
Chunli Ma ◽  
Yanbing Lu ◽  
Xianzhe Wei ◽  
Xiaowen Feng ◽  
...  

A FRET-based ratiometric two-photon fluorescent probe for superoxide anion detection and imaging in cells and tissue was reported with dual-channels.


The Analyst ◽  
2018 ◽  
Vol 143 (23) ◽  
pp. 5799-5804 ◽  
Author(s):  
Wan Sun ◽  
Jing-Xue Cui ◽  
Le-Le Ma ◽  
Zhong-Lin Lu ◽  
Bing Gong ◽  
...  

TP-2Bz, as a nucleus targeting “D–π–A” molecule, was developed as a two-photon turn-on fluorescent probe for the viscosity and GQ DNA detection in cell nuclei.


2017 ◽  
Vol 5 (1) ◽  
pp. 134-138 ◽  
Author(s):  
Jian-Yong Wang ◽  
Zhan-Rong Liu ◽  
Mingguang Ren ◽  
Xiuqi Kong ◽  
Weiying Lin

We developed a novel two-photon fluorescent probe for sensing Cys specifically. The two-photon fluorescent probe exhibited favorable properties and was successfully applied for imaging Cys in living cells and tissues.


2018 ◽  
Vol 42 (11) ◽  
pp. 8325-8329 ◽  
Author(s):  
An Xu ◽  
Yonghe Tang ◽  
Weiying Lin

The first mitochondrial-targeted two-photon fluorescence probe (MT-FA) for formaldehyde (FA) was engineered for monitoring FA in the mitochondria of living cells and liver tissues in one- and two-photon modes.


2019 ◽  
Vol 284 ◽  
pp. 744-750 ◽  
Author(s):  
Carlos Benitez-Martin ◽  
Juan A. Guadix ◽  
John R. Pearson ◽  
Francisco Najera ◽  
Jose M. Perez-Pomares ◽  
...  

The Analyst ◽  
2016 ◽  
Vol 141 (11) ◽  
pp. 3395-3402 ◽  
Author(s):  
Jun-Bin Li ◽  
Qian-Qian Wang ◽  
Lin Yuan ◽  
Yong-Xiang Wu ◽  
Xiao-Xiao Hu ◽  
...  

We report a new two-photon fluorescent probe FATP1 that allows for the two-photon bio-imaging of formaldehyde in live cells and tissues.


2019 ◽  
Vol 43 (7) ◽  
pp. 2865-2869 ◽  
Author(s):  
Kaixin Xu ◽  
Longwei He ◽  
Yunzhen Yang ◽  
Weiying Lin

A two-photon turn-on fluorescent probe regulated by a PET mechanism has been engineered for detection of thiols and H2S in living cells, tissues and zebrafish.


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