ZnO nanoparticle-embedded silk fibroin–polyvinyl alcohol composite film: a potential dressing material for infected wounds

2018 ◽  
Vol 42 (17) ◽  
pp. 14620-14629 ◽  
Author(s):  
Priyanka P. Patil ◽  
Jagruti V. Meshram ◽  
Raghvendra A. Bohara ◽  
Shivdas G. Nanaware ◽  
Shivaji H. Pawar

A highly effective composite film based on ZnO NPs, silk fibroin and PVA for an infected wound.

Molecules ◽  
2019 ◽  
Vol 24 (3) ◽  
pp. 503 ◽  
Author(s):  
Lisha Ai ◽  
Yejing Wang ◽  
Gang Tao ◽  
Ping Zhao ◽  
Ahmad Umar ◽  
...  

Silk sericin (SS) is a type of natural macromolecular protein with excellent hydrophilicity, biocompatibility and biodegradability, but also has very poor mechanical properties. To develop sericin-based wound dressings, we utilized polyvinyl alcohol (PVA) to reinforce the mechanical property of sericin by blending PVA and sericin, then modified zinc oxide nanoparticles (ZnO NPs) on SS/PVA film with the assistance of polydopamine (PDA) to endow SS/PVA film with antibacterial activity. Scanning electron microscopy, energy dispersive spectroscopy and X-ray powder diffraction demonstrated ZnO NPs were well grafted on PDA-SS/PVA film. Fourier transform infrared spectra suggested PDA coating and ZnONPs modification did not alter the structure of sericin and PVA. Water contact angle and swelling tests indicated the excellent hydrophilicity and swellability of ZnO NPs-PDA-SS/PVA composite film. Mass loss analysis showed ZnO NPs-PDA-SS/PVA film had excellent stability. The mechanical performance test suggested the improved tensile strength and elongation at break could meet the requirement of ZnO NPs-PDA-SS/PVA film in biomaterial applications. The antibacterial assay suggested the prepared ZnO NPs-PDA-SS/PVA composite film had a degree of antimicrobial activity against Escherichia coli and Staphylococcus aureus. The excellent hydrophilicity, swellability, stability, mechanical property and antibacterial activity greatly promote the possibility of ZnO NPs-PDA-SS/PVA composite film in antibacterial biomaterials application.


Membranes ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 163 ◽  
Author(s):  
Omed Gh. Abdullah ◽  
Yahya A. K. Salman ◽  
Dana A. Tahir ◽  
Gelas M. Jamal ◽  
Hawzhin T. Ahmed ◽  
...  

Proton conducting nanocomposite solid polymer electrolytes (NSPEs) based on polyvinyl alcohol/ammonium nitrate (PVA/NH4NO3) and different contents of zinc oxide nanoparticles (ZnO-NPs) have been prepared using the casting solution method. The XRD analysis revealed that the sample with 2 wt.% ZnO-NPs has a high amorphous content. The ionic conductivity analysis for the prepared membranes has been carried out over a wide range of frequencies at varying temperatures. Impedance analysis shows that sample with 2 wt.% ZnO-NPs has a smaller bulk resistance compared to that of undoped polymer electrolyte. A small amount of ZnO-NPs was found to enhance the proton-conduction significantly; the highest obtainable room-temperature ionic conductivity was 4.71 × 10−4 S/cm. The effect of ZnO-NP content on the transport parameters of the prepared proton-conducting NSPEs was investigated using the Rice–Roth model; the results reveal that the increase in ionic conductivity is due to an increment in the number of proton ions and their mobility.


Nanomaterials ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. 1797
Author(s):  
Tengteng Ji ◽  
Rong Zhang ◽  
Xiaorong Dong ◽  
Dur E Sameen ◽  
Saeed Ahmed ◽  
...  

Ultrasonication-assisted solution casting was used to prepare polyvinyl alcohol (PVA)/sodium carboxymethyl cellulose (CMC)/nano-ZnO/multilayer graphene nanoplatelet (xGnP) composite films; the performances (mechanical properties, water vapor permeability (WVP), biodegradability and antibacterial activity) of these films were investigated as a function of the ZnO NPs:xGnP mass ratio and ultrasonication time. Intermolecular interactions among ZnO NPs, xGnP and the PVA/CMC matrix were shown to improve WVP, while X-ray diffraction and scanning electron microscopy analyses revealed that the internal reticular structure of ultrasound-treated PVA/CMC/ZnO NPs/xGnP composite films was in a fluffier state than that of the untreated composite films and the PVA/CMC film. The incorporation of ZnO NPs and xGnP into the composite film reduced its tensile strength and elongation at break, and increased antibacterial activity and biodegradability. In addition, we carried out the experiment of strawberry preservation and measured weight loss ratio, firmness, content of total soluble solids and titration acid. Finally, the composite film of 7:3 had the best preservation effect on strawberries. Thus, the obtained results paved the way to develop novel biodegradable composite films with antimicrobial activity for a wide range of applications.


Author(s):  
Yogendra Singh ◽  
B. P. Shukla, ◽  
Supriya Shukla, ◽  
Reshma Jain ◽  
Aditya P. Jaiswal

The present study was conducted on 12 cow calves with infected wounds, irrespective of sex and breed, divided into two groups having 6 cow calves each. The animals of group I were treated with silver nano particle gel and the animals of group II were treated with povidone iodine dressing for 7 consecutive days. Histopathological changes were recorded at different time interval in both the groups. Studies revealed that there was marked re-epitheliazation and hyperplasia with considerable thickening of epidermis and large amount of collagen deposition in granulation tissue in group I as compared to group II. Histopatathological findings clearly suggest that the group treated with silver nano particle gel showed better and faster healing of wound as compared to povidone iodine treated group. Therefore clinical use of silver nano particle gel can be advocated for wound dressing in cow calves.


2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Daiki Itohara ◽  
Kazato Shinohara ◽  
Toshiyuki Yoshida ◽  
Yasuhisa Fujita

Both n-channel and p-channel thin-film transistors have been realized on ZnO nanoparticle (NP) layers sprayed onto quartz substrates. In this study, nitrogen-doped ZnO-NPs were synthesized using an arc-discharge-mediated gas-evaporation method that was recently developed. Sprayed NP layers were characterized by scanning electron microscopy and Hall effect measurements. It was confirmed that p-type behaving NP layers can be obtained using ZnO-NPs synthesized with lower chamber pressure, whereas n-type conductivity can be obtained with higher chamber pressure. pn-junction diodes were also tested, resulting in clear rectifying characteristics. The possibility of particle-process-based ZnO-NP electronics was confirmed.


2014 ◽  
Vol 15 (2) ◽  
pp. 215-219 ◽  
Author(s):  
Se Youn Cho ◽  
Min Eui Lee ◽  
Youngeun Choi ◽  
Hyoung-Joon Jin

2021 ◽  
Vol 20 ◽  
pp. 229-233
Author(s):  
Mei Liu ◽  
Kai Cheng ◽  
Xiangzheng Qin ◽  
Zhenzhong Wei ◽  
Yu Peng ◽  
...  

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