New label-free ultrasensitive electrochemical immunosensor-based Au/MoS2/rGO nanocomposites for CA 27-29 breast cancer antigen detection

2018 ◽  
Vol 42 (13) ◽  
pp. 11046-11053 ◽  
Author(s):  
Nawal A. Alarfaj ◽  
Maha F. El-Tohamy ◽  
Hesham Oraby
Keyword(s):  
Breast Cancer ◽  
Early Diagnosis ◽  
Electrochemical Immunosensor ◽  
Antigen Detection ◽  
Label Free ◽  
Cancer Antigen

Early diagnosis and clinical treatments of breast cancer provide a highly successful chance for patients to survive.

A Label-free Multiplex Electrochemical Biosensor for Detection of Three Breast Cancer Biomarker Proteins Employing Dye/Metal Ions-loaded and Antibodies-Conjugated Polyethyleneimine-Gold Nanoparticles

2021 ◽  
Author(s):  
Kulrisa Kuntamung ◽  
Jaroon Jakmunee ◽  
Kontad Ounnunkad
Keyword(s):  
Breast Cancer ◽  
Electrochemical Biosensor ◽  
Simultaneous Detection ◽  
Growth Factor Receptor ◽  
Cancer Biomarkers ◽  
Electrochemical Immunosensor ◽  
Label Free ◽  
Cancer Antigen ◽  
Breast Cancer Biomarkers ◽  
Epidermal Growth

A new electrochemical immunosensor is developed for the label-free simultaneous detection of mucin1 (MUC1), cancer antigen 15-3 (CA15-3), and human epidermal growth factor receptor 2 (HER2) early breast cancer biomarkers....

scholarly journals Label-Free Identification of Early Stages of Breast Ductal Carcinoma via Multiphoton Microscopy

Scanning ◽  
2020 ◽  
Vol 2020 ◽  
pp. 1-8 ◽  
Author(s):  
Zhong Chen ◽  
Wenhui Guo ◽  
Deyong Kang ◽  
Shu Wang ◽  
Liqin Zheng ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Early Diagnosis ◽  
Ductal Carcinoma In Situ ◽  
Carcinoma In Situ ◽  
Ductal Carcinoma ◽  
Multiphoton Microscopy ◽  
Label Free ◽  
Early Stages ◽  
Cytological Features

Breast cancer can be cured by early diagnosis. Appropriate and effective clinical treatment benefits from accurate pathological diagnosis. However, due to the lack of effective screening and diagnostic imaging methods, early stages of breast cancer often progress to malignant breast cancer. In this study, multiphoton microscopy (MPM) via two-photon excited fluorescence combined with second-harmonic generation was used for identifying the early stages of breast ductal carcinoma. The results showed differences in both cytological features and collagen distribution among normal breast tissue, atypical ductal hyperplasia, low-grade ductal carcinoma in situ, and high-grade ductal carcinoma in situ with microinvasion. Furthermore, three features extracted from the MPM images were used to describe differences in cytological features, collagen density, and basement membrane circumference in the early stages of breast ductal carcinoma. They revealed that MPM has the ability to identify early stages of breast ductal carcinoma label-free, which would contribute to the early diagnosis and treatment of breast cancer. This study may provide the groundwork for the further application of MPM in the clinic.

Multiplexed label-free electrochemical immunosensor for breast cancer precision medicine

2020 ◽  
Vol 1130 ◽  
pp. 60-71
Author(s):  
Suparat Cotchim ◽  
Panote Thavarungkul ◽  
Proespichaya Kanatharana ◽  
Warakorn Limbut
Keyword(s):  
Breast Cancer ◽  
Precision Medicine ◽  
Electrochemical Immunosensor ◽  
Label Free
Sign in / Sign up

Export Citation Format

Share Document