New strategy for the azido–ascorbic acid reaction: a convenient chemosensor and its imaging in garlic slice tissues

2018 ◽  
Vol 42 (9) ◽  
pp. 6707-6712 ◽  
Author(s):  
Dan Zhang ◽  
Na Li ◽  
Yiming Ma ◽  
Ruixue Wang ◽  
Jinyi Wang ◽  
...  

Three chemosensors with azide groups at different sites were designed for rapid detection of ascorbic acid in garlic slice tissues.

RSC Advances ◽  
2014 ◽  
Vol 4 (66) ◽  
pp. 35112 ◽  
Author(s):  
Yirong Zhao ◽  
Yinhui Li ◽  
Yijun Wang ◽  
Jing Zheng ◽  
Ronghua Yang

2021 ◽  
Vol 41 ◽  
pp. 108-120
Author(s):  
M Gallorini ◽  
◽  
R Di Carlo ◽  
S Pilato ◽  
A Ricci ◽  
...  

Human dental pulp stem cell (DPSC) differentiation toward the osteoblastic phenotype is enhanced when culture media are supplemented with differentiating factors, i.e. ascorbic acid, β-glycerophosphate and dexamethasone. Liposomes, spherical vesicles formed by a phospholipid bilayer, are frequently used as carriers for drugs, growth factors and hydrophobic molecules. The aim of this work was to speed up DPSC commitment to the osteogenic lineage by embedding differentiating factors within liposomes. Firstly, liposomes were prepared by rehydrating a phospholipidic thin film and characterised in terms of dimensions. Secondly, liposome-exposed DPSCs were characterised by their immunophenotypic profile. Levels of CD90 were significantly decreased in the presence of liposomes filled with ascorbic acid, β-glycerophosphate and dexamethasone (Lipo-Mix) with respect to normal differentiation medium (DM), while CD73 and CD29 expression were enhanced, suggesting osteogenic commitment. Additionally, an appreciable extracellular matrix deposition is detected. Thirdly, the Lipo-Mix formulation better increases alkaline phosphatase activity and levels of Collagen I secretion with respect to DM. In parallel, the new liposome formulation is capable of decreasing the release of H2O2 and of triggering a precocious antioxidant cell response, redressing the redox balance required upon mesenchymal stem cell commitment to osteogenesis. It can be therefore hypothesised that Lipo-Mix could represent a suitable tool for clinical regenerative purposes in the field of tissue engineering by speeding up DPSC osteogenic commitment, mineralised matrix deposition and remodelling.


RSC Advances ◽  
2021 ◽  
Vol 11 (62) ◽  
pp. 39306-39310
Author(s):  
Qian Gao ◽  
Jing Wan ◽  
Xuejiang Chen ◽  
Xiaomei Mo ◽  
Yao Sun ◽  
...  

A novel colorimetric nanosensor was initially developed for the equipment-free sensitive detection of ascorbic acid based on the Tyndall effect of cobalt hydroxide nanoflakes.


2010 ◽  
Vol 2010 ◽  
pp. 1-6 ◽  
Author(s):  
Dong Liu ◽  
Yang Liu ◽  
Haoqing Hou ◽  
Tianyan You

A novel sonochemical process, using hydrogen peroxide in a laboratory ultrasonic bath, was employed to pretreat the carbon nanofiber (CNF) for creating oxygen-rich groups on the surface of CNF. After the sonochemical process, the CNF showed good hydrophilicity and high electrochemical activity. Compared to normal pretreatment process, this sonochemical process is timesaving and effective for dispersion and functionalization of CNF. The resulting CNF showed high catalytic activity toward the oxidation of DA. A carbon paste electrode modified by CNF (CPE-CNF) was used to determine the dopamine (DA) in the presence of ascorbic acid (AA). The detection limit is 0.05 μM, with the linear range from 0.05 μM to 6.4 μM.


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