Photonic cancer nanomedicine using the near infrared-II biowindow enabled by biocompatible titanium nitride nanoplatforms

2019 ◽  
Vol 4 (2) ◽  
pp. 415-425 ◽  
Author(s):  
Chunmei Wang ◽  
Chen Dai ◽  
Zhongqian Hu ◽  
Hongqiang Li ◽  
Luodan Yu ◽  
...  
Keyword(s):  
Titanium Nitride ◽  
Conversion Efficiency ◽  
Near Infrared ◽  
Photoacoustic Imaging ◽  
Photothermal Conversion ◽  
Theranostic Agent ◽  
Tumor Hyperthermia ◽  
Cancer Nanomedicine

Titanium nitride nanoparticles with high photothermal-conversion efficiency and desirable biocompatibility have been constructed as an alternative theranostic agent for NIR-II laser-excited photoacoustic imaging-guided photothermal tumor hyperthermia.

scholarly journals A Semimetal-Like Molybdenum Carbide Quantum Dots Photoacoustic Imaging and Photothermal Agent with High Photothermal Conversion Efficiency

Materials ◽  
2018 ◽  
Vol 11 (9) ◽  
pp. 1776 ◽  
Author(s):  
Wenhao Dai ◽  
Haifeng Dong ◽  
Xueji Zhang
Keyword(s):  
Quantum Dots ◽  
Conversion Efficiency ◽  
Molybdenum Carbide ◽  
Near Infrared ◽  
Photoacoustic Imaging ◽  
Therapeutic Interventions ◽  
High Concentration ◽  
Photothermal Conversion

Theranostic platforms integrating imaging diagnostic and therapeutic interventions into a single nanoplatform have attracted considerable attention for cancer-individualized therapies. However, their uncertain stability, complex pharmacokinetics, and intrinsic toxicology of multiple components hinder their practical application in clinical research. In this paper, stable and high-concentration molybdenum carbide quantum dots (Mo2C QDs) with a diameter of approximately 6 nm and a topographic height of about 1.5 nm were synthesized using a facile sonication-assisted liquid-phase exfoliation approach. The prepared Mo2C QDs exhibited a strong near-infrared (NIR) absorbance with a high molar extinction coefficient of 4.424 Lg−1cm−1 at 808 nm, a high photothermal conversion efficiency of 42.9%, and showed excellent performance on photoacoustic imaging. The Mo2C QDs had high stability and highly biocompatibility, with low cytotoxicity. Under NIR irradiation, a remarkable in vitro and in vivo therapeutic effect was obtained. Such a stable and biocompatible all-in-one theranostic nanoagent generated by facile synthesis that combines promising imaging guidance and effective tumor ablation properties may hold great potential for theranostic nanomedicine.

MnO2-Coated Porous Pt@CeO2 Core-Shell Nanostructures for Photoacoustic Imaging-Guided Tri-modal Cancer Therapy

Nanoscale ◽  
2021 ◽  
Author(s):  
Qing Xu ◽  
Danyang Li ◽  
Haijun Zhou ◽  
Biaoqi Chen ◽  
Junlei Wang ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Conversion Efficiency ◽  
Photoacoustic Imaging ◽  
Core Shell ◽  
Photothermal Conversion ◽  
The Core ◽  
Shell Nanostructures

We describe the synthesis of MnO2-coated porous Pt@CeO2 core–shell nanostructures (Pt@CeO2@MnO2) as a new theranostic nano-platform. The porous Pt cores endow the core–shell nanostructures with high photothermal conversion efficiency (80%)...

Shape tunable gallium nanorods mediated tumor enhanced ablation through near-infrared photothermal therapy

Nanoscale ◽  
2019 ◽  
Vol 11 (6) ◽  
pp. 2655-2667 ◽  
Author(s):  
Xuyang Sun ◽  
Mengmeng Sun ◽  
Miaomiao Liu ◽  
Bo Yuan ◽  
Weiping Gao ◽  
...  
Keyword(s):  
Liquid Metal ◽  
Metal Nanoparticles ◽  
Conversion Efficiency ◽  
Photothermal Therapy ◽  
Tumor Targeting ◽  
Near Infrared ◽  
Photothermal Conversion

Shape tunable liquid metal nanoparticles were fabricated with characterization of biocompatibility, favorable photothermal conversion efficiency and tumor targeting capability for photothermal therapy.

Multifunctional Cu–Ag2S nanoparticles with high photothermal conversion efficiency for photoacoustic imaging-guided photothermal therapy in vivo

Nanoscale ◽  
2018 ◽  
Vol 10 (2) ◽  
pp. 825-831 ◽  
Author(s):  
Lile Dong ◽  
Guanming Ji ◽  
Yu Liu ◽  
Xia Xu ◽  
Pengpeng Lei ◽  
...  
Keyword(s):  
Conversion Efficiency ◽  
Photothermal Therapy ◽  
Photoacoustic Imaging ◽  
The Novel ◽  
Photothermal Conversion ◽  
Ag2s Nanoparticles

The novel Cu–Ag2S/PVP NPs with high photothermal conversion efficiency could be employed as effective photoacoustic imaging guided photothermal therapy agents.

Regulating morphologies and near-infrared photothermal conversion of perylene bisimide via sequence-dependent peptide self-assembly

2018 ◽  
Vol 54 (18) ◽  
pp. 2208-2211 ◽  
Author(s):  
Lingyun Cui ◽  
Yang Jiao ◽  
Anhe Wang ◽  
Luyang Zhao ◽  
Qianqian Dong ◽  
...  
Keyword(s):  
Conversion Efficiency ◽  
Self Assembly ◽  
Near Infrared ◽  
Aqueous Media ◽  
Radical Anions ◽  
Photothermal Conversion ◽  
Perylene Bisimide ◽  
Sequence Dependent

The behavior of PBI self-assembly can be precisely organised by the conjugation of sequence dependent dipeptides in aqueous media resulting in different assembled nanostructures with improved radical anions yield and enhanced photothermal conversion efficiency.

scholarly journals Recent advances in melanin-like nanomaterials in biomedical applications: a mini review

2019 ◽  
Vol 23 (1) ◽  
Author(s):  
Jihyo Park ◽  
Haeram Moon ◽  
Seonki Hong
Keyword(s):  
Biomedical Applications ◽  
Near Infrared ◽  
Inflammatory Diseases ◽  
Photoacoustic Imaging ◽  
Radical Scavenging ◽  
Main Body ◽  
Photothermal Conversion ◽  
Chemical Structures ◽  
Wide Range ◽  
Analytical Tools

Abstract Background Melanins are a group of biopigments in microorganisms that generate a wide range of colorants. Due to their multifunctionality, including ultraviolet protection, radical scavenging, and photothermal conversion, in addition to their intrinsic biocompatibility, natural melanins and synthetic melanin-like nanomaterials have been suggested as novel nano-bio platforms in biomedical applications. Main body Recent approaches in the synthesis of melanin-like nanomaterials and their biomedical applications have briefly been reviewed. Melanin-like nanomaterials have been suggested as endogenous chromophores for photoacoustic imaging and radical scavengers for the treatment of inflammatory diseases. The photothermal conversion ability of these materials under near-infrared irradiation allows hyperthermia-mediated cancer treatments, and their intrinsic fluorescence can be an indicator in biosensing applications. Furthermore, catechol-rich melanin and melanin-like nanomaterials possess a versatile affinity for various functional organic and inorganic additives, allowing the design of multifunctional hybrid nanomaterials that expand their range of applications in bioimaging, therapy, theranostics, and biosensing. Conclusion Melanin-like natural and synthetic nanomaterials have emerged; however, the under-elucidated chemical structures of these materials are still a major obstacle to the construction of novel nanomaterials through bottom-up approaches and tuning the material properties at the molecular level. Further advancements in melanin-based medical applications can be achieved with the incorporation of next-generation chemical and molecular analytical tools.

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