Shape tunable gallium nanorods mediated tumor enhanced ablation through near-infrared photothermal therapy

Nanoscale ◽  
2019 ◽  
Vol 11 (6) ◽  
pp. 2655-2667 ◽  
Author(s):  
Xuyang Sun ◽  
Mengmeng Sun ◽  
Miaomiao Liu ◽  
Bo Yuan ◽  
Weiping Gao ◽  
...  

Shape tunable liquid metal nanoparticles were fabricated with characterization of biocompatibility, favorable photothermal conversion efficiency and tumor targeting capability for photothermal therapy.

2020 ◽  
Vol 8 (46) ◽  
pp. 10609-10615
Author(s):  
Liwen Hu ◽  
Zikang Chen ◽  
Xiaozhe Su ◽  
Yanshan Liu ◽  
Ting Guo ◽  
...  

An anionic conjugated polyelectrolyte with photothermal conversion efficiency of 56.7% completely inhibited the growth of tumor in 4T1 tumor-bearing mice.


2019 ◽  
Vol 7 (14) ◽  
pp. 2247-2251 ◽  
Author(s):  
Lu Li ◽  
Qingzhu Yang ◽  
Lei Shi ◽  
Nannan Zheng ◽  
Zeyu Li ◽  
...  

Novel phthalocyanine molecule 4OCSPC with deep NIR absorbance showed excellent photothermal therapy property for cancer cells.


2018 ◽  
Vol 54 (96) ◽  
pp. 13599-13602 ◽  
Author(s):  
Zuwu Wei ◽  
Ming Wu ◽  
Shanyou Lan ◽  
Jiong Li ◽  
Xiaolong Zhang ◽  
...  

We designed novel diketopyrrolopyrrole polymer based nanoparticles (DPP-IID-FA), which exhibited strong light absorption and excellent photothermal conversion in the NIR optical window, and displayed high biocompatibility and photostability.


2019 ◽  
Vol 2 (9) ◽  
pp. 3942-3953 ◽  
Author(s):  
Muhammad Rizwan Younis ◽  
Rui Bing An ◽  
Yun-Chao Yin ◽  
Shouju Wang ◽  
Deju Ye ◽  
...  

Nanoscale ◽  
2018 ◽  
Vol 10 (2) ◽  
pp. 825-831 ◽  
Author(s):  
Lile Dong ◽  
Guanming Ji ◽  
Yu Liu ◽  
Xia Xu ◽  
Pengpeng Lei ◽  
...  

The novel Cu–Ag2S/PVP NPs with high photothermal conversion efficiency could be employed as effective photoacoustic imaging guided photothermal therapy agents.


2011 ◽  
Vol 2011 ◽  
pp. 1-7 ◽  
Author(s):  
Hadiyah N. Green ◽  
Dmitry V. Martyshkin ◽  
Cynthia M. Rodenburg ◽  
Eben L. Rosenthal ◽  
Sergey B. Mirov

The mastery of active tumor targeting is a great challenge in near infrared photothermal therapy (NIRPTT). To improve efficiency for targeted treatment of malignant tumors, we modify the technique of conjugating gold nanoparticles to tumor-specific antibodies. Polyethylene glycol-coated (PEGylated) gold nanorods (GNRs) were fabricated and conjugated to an anti-EGFR antibody. We characterized the conjugation efficiency of the GNRs by comparing the efficiency of antibody binding and the photothermal effect of the GNRs before and after conjugation. We demonstrate that the binding efficiency of the antibodies conjugated to the PEGylated GNRs is comparable to the binding efficiency of the unmodified antibodies and 33.9% greater than PEGylated antibody-GNR conjugates as reported by Liao and Hafner (2005). In addition, cell death by NIRPTT was sufficient to kill nearly 90% of tumor cells, which is comparable to NIRPTT with GNRs alone confirming that NIRPTT using GNRs is not compromised by conjugation of GNRs to antibodies.


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