Highly sensitive and rapid visual detection of ricin using unmodified gold nanoparticle probes

RSC Advances ◽  
2014 ◽  
Vol 4 (83) ◽  
pp. 43998-44003 ◽  
Author(s):  
Jingting Hu ◽  
Haichao Dai ◽  
Yujing Sun ◽  
Pengjuan Ni ◽  
Yilin Wang ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Gold Nanoparticle ◽  
Visual Detection ◽  
Nanoparticle Probes ◽  
Highly Sensitive

A sensitive aptamer-based colorimetric biosensor for the detection of ricin using unmodified gold nanoparticles as probe was developed.

A highly sensitive gold nanoparticle bioprobe based electrochemical immunosensor using screen printed graphene biochip

RSC Advances ◽  
2014 ◽  
Vol 4 (102) ◽  
pp. 58460-58466 ◽  
Author(s):  
Syazana Abdullah Lim ◽  
Hiroyuki Yoshikawa ◽  
Eiichi Tamiya ◽  
Hartini Mohd Yasin ◽  
Minhaz Uddin Ahmed
Keyword(s):  
Gold Nanoparticles ◽  
Gold Nanoparticle ◽  
Chorionic Gonadotropin ◽  
Human Chorionic Gonadotropin ◽  
Electrode Material ◽  
Electrochemical Immunosensor ◽  
Highly Sensitive ◽  
Electrochemical Label ◽  
Screen Printed

This study describes a highly sensitive electrochemical immunosensor for the detection of human chorionic gonadotropin (hCG) that uses gold nanoparticles (AuNP) as the electrochemical label and graphene as electrode material.

A gold nanoparticle/latex microsphere-based colorimetric oligonucleotide detection method

2000 ◽  
Vol 72 (1-2) ◽  
pp. 229-235 ◽  
Author(s):  
Robert A. Reynolds ◽  
Chad A. Mirkin ◽  
Robert L. Letsinger
Keyword(s):  
Gold Nanoparticles ◽  
Gold Nanoparticle ◽  
Color Change ◽  
Cellulose Acetate Membrane ◽  
Background Signal ◽  
Nanoparticle Probes ◽  
Red Color ◽  
Oligonucleotide Detection ◽  
Duplex Formation ◽  
Test Result

An exceptionally simple and effective DNA detection methodology based on latex microsphere and gold nanoparticle probes has been developed. The latex and gold particle probes, which were functionalized with separate oligonucleotide sequences, undergo hybridization in the presence of target strands that are complementary to both of the probes. Duplex formation thus results in linking of gold nanoparticles to the latex microspheres and a corresponding white-to-red color change, which, because of the particularly large extinction coefficient of the gold nanoparticles, is clearly visible to the naked eye. Background signal caused by unbound gold nanoparticles is significantly reduced by filtering the solution containing the sample and probes through a size-selective cellulose acetate membrane. The unbound gold probes move freely through this membrane while the larger latex particles are trapped. Therefore, if the latex and gold nanoparticles are joined together via the target oligonucleotides, the membrane appears red, indicating a positive test result. If no hybridization takes place, the membrane appears white, indicating a negative result. The lower detection limits for this system are 500 pM for a 24 base single-stranded target and 2.5 nM for a duplex target oligonucleotide.

Highly sensitive and selective detection of trinitrotoluene using cysteine-capped gold nanoparticles

2016 ◽  
Vol 8 (22) ◽  
pp. 4398-4405 ◽  
Author(s):  
S. Devi ◽  
B. Singh ◽  
A. K. Paul ◽  
S. Tyagi
Keyword(s):  
Gold Nanoparticles ◽  
Gold Nanoparticle ◽  
Cross Linking ◽  
Selective Detection ◽  
Schematic Representation ◽  
Highly Sensitive

(A) A schematic representation of the formation of cysteine capped gold nanoparticles and their interaction at pH 5 and 9.3. (B) A schematic representation of the formation of a Meisenheimer complex between cysteine modified gold nanoparticles and TNT, and possible cross-linking between gold nanoparticles bound to the Meisenheimer complex with gold nanoparticle bound cysteine.

Analyte-triggered autocatalytic amplification combined with gold nanoparticle probes for colorimetric detection of heavy-metal ions

2017 ◽  
Vol 53 (54) ◽  
pp. 7477-7480 ◽  
Author(s):  
Juanhua Yang ◽  
Yun Zhang ◽  
Lang Zhang ◽  
Huili Wang ◽  
Jinfang Nie ◽  
...  
Keyword(s):  
Heavy Metal ◽  
Gold Nanoparticles ◽  
Metal Ions ◽  
Gold Nanoparticle ◽  
Heavy Metal Ions ◽  
Colorimetric Detection ◽  
Detection Limits ◽  
Label Free ◽  
Nanoparticle Probes ◽  
Free Gold

This work reports a new nanosensor based on analyte-triggered autocatalytic amplification and label-free gold nanoparticles for the colorimetric detection of Hg2+, Cu2+and Ag+with detection limits less than 3 nM.

Direct imaging of single gold nanoparticle etching: sensitive detection of lead ions

2014 ◽  
Vol 6 (13) ◽  
pp. 4507-4511 ◽  
Author(s):  
Dinggui Dai ◽  
Dong Xu ◽  
Xiaodong Cheng ◽  
Yan He
Keyword(s):  
Gold Nanoparticles ◽  
Real Time ◽  
Gold Nanoparticle ◽  
Detection Method ◽  
Size Reduction ◽  
Direct Imaging ◽  
Real Time Imaging ◽  
Highly Sensitive ◽  
Darkfield Microscopy

We present a highly sensitive Pb2+ detection method by in situ real-time imaging of Pb2+ catalyzed etching and size reduction of immobilized single gold nanoparticles with darkfield microscopy.

Fast Colorimetric Detection of Copper Ions Using L-Cysteine Functionalized Gold Nanoparticles

2007 ◽  
Vol 7 (2) ◽  
pp. 712-716 ◽  
Author(s):  
Wenrong Yang ◽  
J. Justin Gooding ◽  
Zhicong He ◽  
Qiong Li ◽  
Guonan Chen
Keyword(s):  
Aqueous Solution ◽  
Gold Nanoparticles ◽  
Gold Nanoparticle ◽  
Surface Plasmon ◽  
Visual Detection ◽  
Detection Method ◽  
Copper Ions ◽  
Colorimetric Detection ◽  
Sandwich Complex ◽  
Functionalized Gold Nanoparticles

This communication reports an efficient visual detection method of Cu2+ by L-cysteine functionalized gold nanoparticles in aqueous solution. Upon exposure to Cu2+, the gold nanoparticle solution changed from red to blue, in response to surface plasmon absorption of dispersed and aggregated nanoparticles. This colorimetric sensor allows a rapid quantitative assay of Cu2+ down to the concentration range of 10−5 M. Recognition of Cu2+ and formation of the aggregates are proposed to occur via a 2 : 1 sandwich complex between L-cysteine and Cu2+.

Highly sensitive electrochemical sensor for dopamine with a double-stranded deoxyribonucleic acid/gold nanoparticle/graphene modified electrode

2015 ◽  
Vol 7 (5) ◽  
pp. 1878-1883 ◽  
Author(s):  
Wencheng Wang ◽  
Yong Cheng ◽  
Lijun Yan ◽  
Huanhuan Zhu ◽  
Guangjiu Li ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Ionic Liquid ◽  
Electrochemical Sensor ◽  
Gold Nanoparticle ◽  
Modified Electrode ◽  
Deoxyribonucleic Acid ◽  
Carbon Ionic Liquid Electrode ◽  
Liquid Electrode ◽  
Highly Sensitive

A highly sensitive electrochemical sensor for the detection of dopamine was realized with a double-stranded deoxyribonucleic acid/gold nanoparticles/graphene modified carbon ionic liquid electrode.

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