Recent advances in arsenic metabolism in plants: current status, challenges and highlighted biotechnological intervention to reduce grain arsenic in rice

Metallomics ◽  
2019 ◽  
Vol 11 (3) ◽  
pp. 519-532 ◽  
Author(s):  
Manju Shri ◽  
Pradyumna Kumar Singh ◽  
Maria Kidwai ◽  
Neelam Gautam ◽  
Sonali Dubey ◽  
...  
Keyword(s):  
Toxic Effects ◽  
Current Status ◽  
Arsenic Metabolism ◽  
Recent Advances

Arsenic (As), classified as a “metalloid” element, is well known for its carcinogenicity and other toxic effects to humans.

scholarly journals Do nitric oxide, carbon monoxide and hydrogen sulfide really qualify as ‘gasotransmitters’ in bacteria?

2018 ◽  
Vol 46 (5) ◽  
pp. 1107-1118 ◽  
Author(s):  
Lauren K. Wareham ◽  
Hannah M. Southam ◽  
Robert K. Poole
Keyword(s):  
Nitric Oxide ◽  
Carbon Monoxide ◽  
Hydrogen Sulfide ◽  
Small Molecule ◽  
Toxic Effects ◽  
Gaseous Molecule ◽  
Recent Advances ◽  
Definition Of

A gasotransmitter is defined as a small, generally reactive, gaseous molecule that, in solution, is generated endogenously in an organism and exerts important signalling roles. It is noteworthy that these molecules are also toxic and antimicrobial. We ask: is this definition of a gasotransmitter appropriate in the cases of nitric oxide, carbon monoxide and hydrogen sulfide (H2S) in microbes? Recent advances show that, not only do bacteria synthesise each of these gases, but the molecules also have important signalling or messenger roles in addition to their toxic effects. However, strict application of the criteria proposed for a gasotransmitter leads us to conclude that the term ‘small molecule signalling agent’, as proposed by Fukuto and others, is preferable terminology.

scholarly journals Genome editing in large animals: current status and future prospects

2019 ◽  
Vol 6 (3) ◽  
pp. 402-420 ◽  
Author(s):  
Jianguo Zhao ◽  
Liangxue Lai ◽  
Weizhi Ji ◽  
Qi Zhou
Keyword(s):  
Regenerative Medicine ◽  
Genome Editing ◽  
Biomedical Research ◽  
Human Disease ◽  
Gene Editing ◽  
Disease Modeling ◽  
Current Status ◽  
Future Prospects ◽  
Recent Advances ◽  
Large Animals

AbstractLarge animals (non-human primates, livestock and dogs) are playing important roles in biomedical research, and large livestock animals serve as important sources of meat and milk. The recently developed programmable DNA nucleases have revolutionized the generation of gene-modified large animals that are used for biological and biomedical research. In this review, we briefly introduce the recent advances in nuclease-meditated gene editing tools, and we outline these editing tools’ applications in human disease modeling, regenerative medicine and agriculture. Additionally, we provide perspectives regarding the challenges and prospects of the new genome editing technology.

scholarly journals The Current Status of Research on Gibberellin Biosynthesis

2020 ◽  
Vol 61 (11) ◽  
pp. 1832-1849 ◽  
Author(s):  
Peter Hedden
Keyword(s):  
Gibberellic Acid ◽  
Vascular Plants ◽  
Molecular Mechanisms ◽  
Bacterial Species ◽  
Current Status ◽  
Fusarium Fujikuroi ◽  
Environmental Cues ◽  
Gibberellin Biosynthesis ◽  
Gibberellin Metabolism ◽  
Recent Advances

Abstract Gibberellins are produced by all vascular plants and several fungal and bacterial species that associate with plants as pathogens or symbionts. In the 60 years since the first experiments on the biosynthesis of gibberellic acid in the fungus Fusarium fujikuroi, research on gibberellin biosynthesis has advanced to provide detailed information on the pathways, biosynthetic enzymes and their genes in all three kingdoms, in which the production of the hormones evolved independently. Gibberellins function as hormones in plants, affecting growth and differentiation in organs in which their concentration is very tightly regulated. Current research in plants is focused particularly on the regulation of gibberellin biosynthesis and inactivation by developmental and environmental cues, and there is now considerable information on the molecular mechanisms involved in these processes. There have also been recent advances in understanding gibberellin transport and distribution and their relevance to plant development. This review describes our current understanding of gibberellin metabolism and its regulation, highlighting the more recent advances in this field.

Recent advances and therapeutic journey of coumarins: current status and perspectives

2015 ◽  
Vol 24 (7) ◽  
pp. 2771-2798 ◽  
Author(s):  
Kuldipsinh P. Barot ◽  
Shailesh V. Jain ◽  
Laurent Kremer ◽  
Shubhra Singh ◽  
Manjunath D. Ghate
Keyword(s):  
Current Status ◽  
Recent Advances

Robotic Surgery for Colon and Rectal Cancer: Current Status, Recent Advances, and Future Directions

2017 ◽  
Vol 13 (1) ◽  
pp. 37-44 ◽  
Author(s):  
Ajit Pai ◽  
George Melich ◽  
Slawomir J. Marecik ◽  
John J. Park ◽  
Leela M. Prasad
Keyword(s):  
Rectal Cancer ◽  
Robotic Surgery ◽  
Current Status ◽  
Future Directions ◽  
Recent Advances ◽  
Colon And Rectal Cancer
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