Stable and sensitive stimuli-responsive anisotropic hydrogels for sensing ionic strength and pressure

2018 ◽  
Vol 5 (6) ◽  
pp. 1076-1081 ◽  
Author(s):  
Takayuki Hiratani ◽  
Osamu Kose ◽  
Wadood Y. Hamad ◽  
Mark J. MacLachlan

Stimuli-responsive hydrogels that respond to pressure and ionic strength were prepared with large mono-domain, nematic organization of cellulose nanocrystals (CNCs).

2014 ◽  
Vol 1622 ◽  
pp. 153-159
Author(s):  
Jeffrey S. Bates ◽  
Jules J. Magda

ABSTRACTResearchers have investigated hydrogels as potential materials for biological monitoring. Hydrogel compositions have been designed to respond to changes in temperature, pH, glucose concentration and ionic strength concentration. Hydrogels designed to respond to changes in environmental conditions have demonstrated their ability to respond via a swelling or shrinking action. This swelling behavior can be exploited using a variety of signal transduction methods. While this technology shows promise, the degradation of hydrogel materials has not yet been characterized with respect to the shelf life of hydrogel samples or to their use in continuous testing. A series of experiments were performed to test hydrogels stored for extended periods of time then subjected to oscillatory testing, and the results have been analyzed to determine whether hydrogels can be used for extended periods of time for biological sensing applications.


Cancers ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 1164
Author(s):  
Fernanda Andrade ◽  
Maria Mercé Roca-Melendres ◽  
Esteban F. Durán-Lara ◽  
Diana Rafael ◽  
Simó Schwartz

Cancer remains as the second leading cause of death, worldwide. Despite the enormous important advances observed in the last decades, advanced stages of the disease remain incurable. The severe side effects associated to systemic high doses of chemotherapy and the development of drug resistance impairs a safe and efficiency anticancer therapy. Therefore, new formulations are continuously under research and development to improve anticancer drugs therapeutic index through localized delivery at tumor sites. Among a wide range of possibilities, hydrogels have recently gained special attention due to their potential to allow in situ sustained and controlled anticancer drug release. In particular, stimuli-responsive hydrogels which are able to change their physical state from liquid to gel accordingly to external factors such as temperature, pH, light, ionic strength, and magnetic field, among others. Some of these formulations presented promising results for the localized control and treatment of cancer. The present work aims to discuss the main properties and application of stimuli-responsive hydrogels in cancer treatment and summarize the most important advances observed in the last decades focusing on the use of pH-, light-, ionic strength-, and magnetic-responsive hydrogels.


2019 ◽  
Vol 4 (1) ◽  
pp. 91-102 ◽  
Author(s):  
Ryan T. Shafranek ◽  
Joel D. Leger ◽  
Song Zhang ◽  
Munira Khalil ◽  
Xiaodan Gu ◽  
...  

Directed self-assembly in polymeric hydrogels allows tunability of thermal response and viscoelastic properties.


Author(s):  
Ana C. Marques ◽  
Paulo J. Costa ◽  
Sérgia Velho ◽  
Maria H. Amaral

2018 ◽  
Vol 229 (9) ◽  
pp. 3715-3725 ◽  
Author(s):  
C. C. Benjamin ◽  
R. S. Lakes ◽  
W. C. Crone

Soft Matter ◽  
2015 ◽  
Vol 11 (18) ◽  
pp. 3512-3529 ◽  
Author(s):  
Juntao Tang ◽  
Patrick James Quinlan ◽  
Kam Chiu Tam

Pickering emulsions with stimuli-responsive properties have, in recent years, received a considerable amount of attention. This paper provides a concise and comprehensive review of Pickering emulsion systems that possess the ability to respond to an array of external triggers, including pH, temperature, CO2concentration, light intensity, ionic strength, and magnetic field intensity.


Sign in / Sign up

Export Citation Format

Share Document