scholarly journals SERS-based droplet microfluidics for high-throughput gradient analysis

Lab on a Chip ◽  
2019 ◽  
Vol 19 (4) ◽  
pp. 674-681 ◽  
Author(s):  
Jinhyeok Jeon ◽  
Namhyun Choi ◽  
Hao Chen ◽  
Joung-Il Moon ◽  
Lingxin Chen ◽  
...  

We report a fully integrated SERS-based microdroplet platform for simultaneous detection of various concentrations of a reagent.

2019 ◽  
Vol 338 ◽  
pp. 72-80 ◽  
Author(s):  
L. Silvester ◽  
F. Ramos ◽  
J. Thuriot-Roukos ◽  
S. Heyte ◽  
M. Araque ◽  
...  

Lab on a Chip ◽  
2018 ◽  
Vol 18 (5) ◽  
pp. 775-784 ◽  
Author(s):  
Hui-Sung Moon ◽  
Kwanghwi Je ◽  
Jae-Woong Min ◽  
Donghyun Park ◽  
Kyung-Yeon Han ◽  
...  

We developed a modified high-throughput droplet barcoding technique for single-cell Drop-Seq via introduction of hydrodynamic ordering in a spiral microchannel.


2014 ◽  
Vol 8 (4) ◽  
pp. 041102 ◽  
Author(s):  
Raluca Ostafe ◽  
Radivoje Prodanovic ◽  
W. Lloyd Ung ◽  
David A. Weitz ◽  
Rainer Fischer

2021 ◽  
Author(s):  
Leyla Amirifar ◽  
Mohsen Besanjideh ◽  
Rohollah Nasiri ◽  
Amir Shamloo ◽  
Fatemeh Nasrollahi ◽  
...  

Abstract Droplet-based microfluidic systems have been employed to manipulate discrete fluid volumes with immiscible phases. Creating the fluid droplets at microscale has led to a paradigm shift in mixing, sorting, encapsulation, sensing, and designing high throughput devices for biomedical applications. Droplet microfluidics has opened many opportunities in microparticle synthesis, molecular detection, diagnostics, drug delivery, and cell biology. In the present review, we first introduce standard methods for droplet generation (i.e., passive and active methods) and discuss the latest examples of emulsification and particle synthesis approaches enabled by microfluidic platforms. Then, the applications of droplet-based microfluidics in different biomedical applications are detailed. Finally, a general overview of the latest trends along with the perspectives and future potentials in the field are provided.


2012 ◽  
Vol 45 (3) ◽  
pp. 489-495 ◽  
Author(s):  
Clement E. Blanchet ◽  
Alexey V. Zozulya ◽  
Alexey G. Kikhney ◽  
Daniel Franke ◽  
Peter V. Konarev ◽  
...  

A setup is presented for automated high-throughput measurements of small-angle X-ray scattering (SAXS) from macromolecular solutions on the bending-magnet beamline X33 of EMBL at the storage ring DORIS-III (DESY, Hamburg). A new multi-cell compartment allows for rapid switching between in-vacuum and in-air operation, for digital camera assisted control of cell filling and for colour sample illumination. The beamline is equipped with a Pilatus 1 M-W pixel detector for SAXS and a Pilatus 300 k-W for wide-angle scattering (WAXS), and results from the use of the Pilatus detectors for scattering studies are reported. The setup provides a broad resolution range from 100 to 0.36 nm without the necessity of changing the sample-to-detector distance. A new optimized robotic sample changer is installed, permitting rapid and reliable automated sample loading and cell cleaning with a required sample volume of 40 µl. All the devices are fully integrated into the beamline control software system, ensuring fully automated and user-friendly operation (attended, unattended and remote) with a throughput of up to 15 measurements per hour.


2011 ◽  
Vol 10 (1) ◽  
pp. 282 ◽  
Author(s):  
Céline Barnadas ◽  
David Kent ◽  
Lincoln Timinao ◽  
Jonah Iga ◽  
Laurie R Gray ◽  
...  

IBRO Reports ◽  
2019 ◽  
Vol 6 ◽  
pp. S136
Author(s):  
Marco Malaga ◽  
John Heyman ◽  
Jesse Collins ◽  
Alison O’Neil ◽  
Qiaoling Huang ◽  
...  

Talanta ◽  
2011 ◽  
Vol 85 (2) ◽  
pp. 1160-1165 ◽  
Author(s):  
Pu Su ◽  
Nan Liu ◽  
Maoxiang Zhu ◽  
Baoan Ning ◽  
Ming Liu ◽  
...  

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