Microfluidics within a well: an injection-molded plastic array 3D culture platform

Lab on a Chip ◽  
2018 ◽  
Vol 18 (16) ◽  
pp. 2433-2440 ◽  
Author(s):  
Younggyun Lee ◽  
Jin Woo Choi ◽  
James Yu ◽  
Dohyun Park ◽  
Jungmin Ha ◽  
...  

A versatile injection-molded platform with fast, robust, and simple liquid patterning capable of 3D co-culture experiments.

Lab on a Chip ◽  
2019 ◽  
Vol 19 (12) ◽  
pp. 2071-2080 ◽  
Author(s):  
Somin Lee ◽  
Jungeun Lim ◽  
James Yu ◽  
Jungho Ahn ◽  
Younggyun Lee ◽  
...  

Recent advances in microfluidic organ-on-a-chip technology have enabled the growth of 3D microphysiological systems for diverse biological studies.


2021 ◽  
Vol 1019 ◽  
pp. 205-210
Author(s):  
Deepika S. Singraur ◽  
Bhushan T. Patil ◽  
Vasim A. Shaikh

The cooling process is an essential aspect while designing for uniform heat transfer between the mold and the molded part. Improper design and placement of cooling channels result in non-uniform cooling and thus results in differential shrinkage and warpage on the final product. The installation of the channels yet plays a crucial role in the cooling of the part. Conforming channels that are placed at an optimum distance from the part to enhance the cooling process. In this paper, the performance parameters of straight drilled channels are compared with the conformal cooling channels for an electric alarm box. The analysis indicates that the conformal cooling method improved and enhanced the cooling process and reduced the defects like warpage and differential shrinkage by 25.5% and 28.0% respectively.


Author(s):  
Morimasa Nakamura ◽  
Atsushi Katayama ◽  
Ichiro Moriwaki

A hot-roll finishing was proposed as a simple finishing method for plastic gears. In the hot-roll finishing, plastic work gears are finished by meshing with a heated copper die wheel. In the previous study, a hot-roll finishing rig for plastic gears was developed, and it was confirmed that tooth profiles of hobbed plastic gears are improved by the finishing. Thus, the hot-roll finishing could also be effective for injection-molded plastic gears. In the present paper, appropriate hot-roll finishing procedures for injection-molded polyoxymethylene (POM) helical gears were pursued. In the injection molding, an inadequate mold easily allows large slope deviations on a tooth profile and trace. The hot-roll finishing can reduce the slope deviations, but induces form deviations especially on the profile. Tests of injection-molded and hot-roll-finished plastic gears were performed on a self-produced gear roller test rig and a self-produced fatigue rig, and a transmission error and load capacity were estimated. Compared with injection-molded gears, hot-roll-finished plastic gears showed small transmission error, while a load capacity was at the almost same level. As a result, the hot-roll finishing is effective for improving a transmission error of injection-molded plastic gears.


2016 ◽  
Vol 10 (3) ◽  
pp. 173-180
Author(s):  
Marek Jałbrzykowski

Abstract This paper presents the problem of thermal degradation of thermoplastic materials processed using the injection method. Attention was paid to the issue of the optimal selection of a dye for modifying the base materials. For the selected materials and dyes, derivatograph tests were performed in order to assess their thermal characteristics and breakdown kinetics. Additionally, tribological tests and microscope observations of selected samples were performed. The obtained test results suggest a diverse level of thermal processes in the analyzed materials. This is crucial for the appropriate selection of dyes for plastic materials. As it turned out, the tribological properties of materials can also influence the technological quality of the injected alloy.


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