scholarly journals Macroscale precipitation kinetics: towards complex precipitate structure design

2018 ◽  
Vol 20 (30) ◽  
pp. 19768-19775 ◽  
Author(s):  
Nirmali Prabha Das ◽  
Brigitta Müller ◽  
Ágota Tóth ◽  
Dezső Horváth ◽  
Gábor Schuszter
Keyword(s):  
Pharmaceutical Industry ◽  
Materials Science ◽  
Structure Design ◽  
Precipitation Kinetics ◽  
Self Assembled ◽  
Precipitate Structure ◽  
The Way

Producing self-assembled inorganic precipitate micro- and macro-structures with tailored properties may pave the way for new possibilities in, e.g., materials science and the pharmaceutical industry.

scholarly journals Synthesis and Characterization of a Bioconjugate Based on Oleic Acid and L-Cysteine

Polymers ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 1791
Author(s):  
Marco Vizcarra-Pacheco ◽  
María Ley-Flores ◽  
Ana Mizrahim Matrecitos-Burruel ◽  
Ricardo López-Esparza ◽  
Daniel Fernández-Quiroz ◽  
...  
Keyword(s):  
Oleic Acid ◽  
Materials Science ◽  
Critical Micellar Concentration ◽  
Synthesis And Characterization ◽  
New Materials ◽  
Visible Spectroscopy ◽  
Amide Bonds ◽  
Transmission Electron ◽  
Self Assembled

One of the main challenges facing materials science today is the synthesis of new biodegradable and biocompatible materials capable of improving existing ones. This work focused on the synthesis of new biomaterials from the bioconjugation of oleic acid with L-cysteine using carbodiimide. The resulting reaction leads to amide bonds between the carboxylic acid of oleic acid and the primary amine of L-cysteine. The formation of the bioconjugate was corroborated by Fourier transform infrared spectroscopy (FTIR), Raman spectroscopy, and nuclear magnetic resonance (NMR). In these techniques, the development of new materials with marked differences with the precursors was confirmed. Furthermore, NMR has elucidated a surfactant structure, with a hydrophilic part and a hydrophobic section. Ultraviolet-visible spectroscopy (UV-Vis) was used to determine the critical micellar concentration (CMC) of the bioconjugate. Subsequently, light diffraction (DLS) was used to analyze the size of the resulting self-assembled structures. Finally, transmission electron microscopy (TEM) was obtained, where the shape and size of the self-assembled structures were appreciated.

scholarly journals Infinite supramolecular pseudo-polyrotaxane with poly[3]catenane axle: assembling nanosized rings from mono- and diatomic I− and I2 tectons

2020 ◽  
Vol 56 (4) ◽  
pp. 551-554 ◽  
Author(s):  
Matteo Savastano ◽  
Carla Bazzicalupi ◽  
Cristina Gellini ◽  
Antonio Bianchi
Keyword(s):  
Solid State ◽  
Self Assembled ◽  
The Way

Self-assembled infinite supramolecular pseudo-polyrotaxane with a poly[3]catenate axle sets a new goal for the complexity of polyiodide architectures, paving the way to solid-state conductors.

Recent developments in sulfur–carbon bond formation reaction involving thiosulfates

2017 ◽  
Vol 15 (9) ◽  
pp. 1942-1946 ◽  
Author(s):  
Zongjun Qiao ◽  
Xuefeng Jiang
Keyword(s):  
Pharmaceutical Industry ◽  
Organic Molecules ◽  
Materials Science ◽  
Bond Formation ◽  
Food Chemistry ◽  
Formation Reaction ◽  
Carbon Bond ◽  
Recent Developments ◽  
Sulfur Containing

Sulfur–carbon bond construction has gained great attention recently since sulfur-containing organic molecules serve important functions in the pharmaceutical industry, agrochemistry, food chemistry, and materials science.

scholarly journals Nanoscale electromechanical properties of template-assisted hierarchical self-assembled cellulose nanofibers

Nanoscale ◽  
2018 ◽  
Vol 10 (35) ◽  
pp. 16812-16821 ◽  
Author(s):  
Yonatan Calahorra ◽  
Anuja Datta ◽  
James Famelton ◽  
Doron Kam ◽  
Oded Shoseyov ◽  
...  
Keyword(s):  
Cellulose Nanofibers ◽  
Electromechanical Properties ◽  
Self Assembled ◽  
Wetting Process ◽  
Template Wetting ◽  
The Way

Hierarchical self-assembled cellulose nanofibers, fabricated using a template-wetting process, are shown to exhibit distinct shear piezoelectricity, paving the way towards engineered nanofibers with tailor-made electromechanical properties.

scholarly journals Ternary MOF-on-MOF heterostructures with controllable architectural and compositional complexity via multiple selective assembly

2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Chao Liu ◽  
Qiang Sun ◽  
Lina Lin ◽  
Jing Wang ◽  
Chaoqi Zhang ◽  
...  
Keyword(s):  
Rational Design ◽  
Materials Science ◽  
Metal Organic Framework ◽  
Building Blocks ◽  
Selective Assembly ◽  
Assembly Strategy ◽  
Metal Organic ◽  
Site Selective ◽  
Organic Framework ◽  
The Way

Abstract Assembly of different metal-organic framework (MOF) building blocks into hybrid MOF-on-MOF heterostructures is promising in chemistry and materials science, however the development of ternary MOF-on-MOF heterostructures with controllable architectural and compositional complexity is challenging. Here we report the synthesis of three types of ternary MOF-on-MOF heterostructures via a multiple selective assembly strategy. This strategy relies on the choice of one host MOF with more than one facet that can arrange the growth of a guest MOF, where the arrangement is site-selective without homogenous growth of guest MOF or homogenous coating of guest on host MOF. The growth of guest MOF on a selected site of host MOF in each step provides the opportunity to further vary the combinations of arrangements in multiple steps, leading to ternary MOF-on-MOF heterostructures with tunable complexity. The developed strategy paves the way towards the rational design of intricate and unprecedented MOF-based superstructures for various applications.

scholarly journals Techniques for Combinatorial and High-Throughput Microscopy Part 1: Gradient Specimen Fabrication for Poiymer Thin Film Research

2003 ◽  
Vol 11 (5) ◽  
pp. 26-31 ◽  
Author(s):  
A. Sehgal ◽  
A. Karim ◽  
C. Stafford ◽  
M. Fasolka
Keyword(s):  
Thin Film ◽  
Pharmaceutical Industry ◽  
High Throughput ◽  
Materials Science ◽  
Complex Materials ◽  
Huge Number ◽  
Film Research ◽  
Highly Efficient ◽  
Experimental Parameters ◽  
Materials Research

Combinatorial and high-throughput (C&HT) approaches accelerate research by addressing multiple experimental parameters in a parallel or otherwise highly efficient fashion. First used by the pharmaceutical industry for product discovery, the C&HT paradigm is being extended to the study of complex materials systems that require measurements of properties and phenomena over a huge number of conditions. As with traditional materials science, microscopy and imaging of morphology are essential for C&HT materials research.

scholarly journals Multifunctional DNA Nanomaterials for Biomedical Applications

2015 ◽  
Vol 2015 ◽  
pp. 1-21 ◽  
Author(s):  
Dick Yan Tam ◽  
Pik Kwan Lo
Keyword(s):  
Targeted Delivery ◽  
Materials Science ◽  
Drug Loading ◽  
Dna Nanotechnology ◽  
Control Release ◽  
Structural Features ◽  
Cellular Systems ◽  
Triggered Release ◽  
Self Assembled

The rapidly emerging DNA nanotechnology began with pioneer Seeman’s hypothesis that DNA not only can carry genetic information but also can be used as molecular organizer to create well-designed and controllable nanomaterials for applications in materials science, nanotechnology, and biology. DNA-based self-assembly represents a versatile system for nanoscale construction due to the well-characterized conformation of DNA and its predictability in the formation of base pairs. The structural features of nucleic acids form the basis of constructing a wide variety of DNA nanoarchitectures with well-defined shapes and sizes, in addition to controllable permeability and flexibility. More importantly, self-assembled DNA nanostructures can be easily functionalized to construct artificial functional systems with nanometer scale precision for multipurposes. Apparently scientists envision artificial DNA-based nanostructures as tool for drug loading andin vivotargeted delivery because of their abilities in selective encapsulation and stimuli-triggered release of cargo. Herein, we summarize the strategies of creating multidimensional self-assembled DNA nanoarchitectures and review studies investigating their stability, toxicity, delivery efficiency, loading, and control release of cargos in addition to their site-specific targeting and delivery of drug or cargo molecules to cellular systems.

Approaches to an Integrated Undergraduate Education in Materials Science and Engineering

1985 ◽  
Vol 66 ◽  
Author(s):  
Merton C. Flemings ◽  
Donald R. Sadoway
Keyword(s):  
Undergraduate Education ◽  
Materials Science ◽  
Science And Engineering ◽  
Technological Advances ◽  
Electrical Engineers ◽  
Materials Science And Engineering ◽  
Scientists And Engineers ◽  
Research And Education ◽  
The Way

This is an era of great excitement and opportunity in the materials field, particularly for those of us in universities. Our field has expanded greatly in recent years. Materials scientists and engineers have joined forces with physicists, chemists, electrical engineers and others to pave the way for major technological advances. Remarkable strides in instrumentation have brought insights unimagined a decade ago. The realization is growing in so many other fields of research and education that further advances are limited largely by the capabilities of materials. There is no field of engineering that could not improve the efficiency or performance of its products, if better materials were available.

scholarly journals AN OVERVIEW OF ANALYTICAL INSTRUMENT QUALIFICATION WITH REFERENCE OF PHARMACEUTICAL INDUSTRY

2018 ◽  
Vol 8 (5) ◽  
pp. 99-103 ◽  
Author(s):  
Devesh Kapoor ◽  
Ruchi B. Vyas ◽  
Diwaker Dadrwal
Keyword(s):  
Pharmaceutical Industry ◽  
Laboratory Equipment ◽  
Voluntary Standards ◽  
Analytical Instruments ◽  
Intended Purpose ◽  
System Suitability ◽  
Design Qualification ◽  
Operational Qualification ◽  
Performance Qualification ◽  
The Way

In the most general sense, validation refers to a process that consists of at least four distinct components or steps: software, instruments, methods or procedures, and system suitability The system, the software, and the method must all be validated, and system suitability is used to keep the process in check. But while the overall process is called validation, some of the steps also are referred to by that same term, as well as other steps such as qualification and verification. Analytical instruments are used for a specific analysis. So regular performance verifications are made to ensure that the instrument to be used is suitable for its intended application. All equipments used in the production of products shall be properly Validated and Calibrated to demonstrate that it is suitable for its intended purpose. The current equipment qualification programs and procedures used within the pharmaceutical industry are based on regulatory requirements, voluntary standards, vendor practices, and industry practices. The result is considerable variation in the way pharmaceutical companies approach the qualification of laboratory equipment and the way they interpret the often vague requirements. The process for instrument qualification follows the 4Qs model approach. It include design qualification (DQ), Installation qualification (IQ), Operational qualification (OQ), Performance qualification (PQ). The goal of any regulated laboratory is to provide reliable and valid data suitable for its intended purpose. Analysts use validated methods, system suitability tests, and in-process quality control checks to ensure that the data they acquire are reliable and that there are specific guidance and procedures available to ensure compliance. Keywords: Qualification, FDA, Instruments, Validation, Calibration, Documentation

Programmable, self-assembled DNA nanodevices for cellular programming and tissue engineering

Nanoscale ◽  
2021 ◽  
Author(s):  
Ankit Gangrade ◽  
Nicholas Stephanopoulos ◽  
Dhiraj Devidas Bhatia
Keyword(s):  
Tissue Engineering ◽  
Supramolecular Chemistry ◽  
Materials Science ◽  
Dynamic Field ◽  
Self Assembled

DNA-based nanotechnology has evolved into an autonomous, highly innovative, and dynamic field of research at the nexus of supramolecular chemistry, nanotechnology, materials science, and biotechnology. DNA-based materials, including origami nanodevices,...

Sign in / Sign up

Export Citation Format

Share Document